Ensembl ID ENSG00000184363 Gene ID 11187 Accession 9025
Gene Symbol PKP3 Alias NA Full Name plakophilin 3
Position 11 : 392614 - 404908 Length 12295 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

ENSG00000184363 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000184363 PKP3 1.29 1.42e-48 BRCA
ENSG00000184363 PKP3 2.35 5.58e-82 LUSC
ENSG00000184363 PKP3 0.90 1.84e-26 PRAD
ENSG00000184363 PKP3 2.14 6.31e-33 UCEC
ENSG00000184363 PKP3 5.17 1.01e-15 CHOL
ENSG00000184363 PKP3 4.56 2.07e-17 CESC
ENSG00000184363 PKP3 1.56 1.68e-43 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000184363 PKP3 oropharyngeal tumors 12827610
ENSG00000184363 PKP3 lung cancer 16103059
ENSG00000184363 PKP3 cancer 17391671
ENSG00000184363 PKP3 tumors 18729189
ENSG00000184363 PKP3 cancer 18801625
ENSG00000184363 PKP3 prostate cancer 20348237
ENSG00000184363 PKP3 cancer 20501752
ENSG00000184363 PKP3 tumors 20671973
ENSG00000184363 PKP3 Gastric Cancers 21194493
ENSG00000184363 PKP3 breast cancers 21947748
ENSG00000184363 PKP3 bladder cancer 22119253
ENSG00000184363 PKP3 tumor 22701666
ENSG00000184363 PKP3 tumor 25501895
ENSG00000184363 PKP3 tumor 25875355
ENSG00000184363 PKP3 tumor 29377892
ENSG00000184363 PKP3 tumors 29722422
ENSG00000184363 PKP3 tumour 29803740
ENSG00000184363 PKP3 lung cancer 29855376
ENSG00000184363 PKP3 tumor 30144176
ENSG00000184363 PKP3 ovarian cancer 30527804
ENSG00000184363 PKP3 ovarian cancer 30855445
ENSG00000184363 PKP3 tumor 31129920
ENSG00000184363 PKP3 tumor 31425296
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000184363 PKP3 MESO 3e-04 high
ENSG00000184363 PKP3 STAD 0.013 low
ENSG00000184363 PKP3 PAAD 0.0012 high
ENSG00000184363 PKP3 UCEC 0.018 low
ENSG00000184363 PKP3 ACC 0.01 high
ENSG00000184363 PKP3 LUSC 0.0025 high
ENSG00000184363 PKP3 HNSC 0.03 low
ENSG00000184363 PKP3 KICH 0.025 low
ENSG00000184363 PKP3 THYM 0.0094 high
ENSG00000184363 PKP3 BRCA 0.034 low
ENSG00000184363 PKP3 COAD 0.0074 high
ENSG00000184363 PKP3 OV 0.0062 high
ENSG00000184363 PKP3 BLCA 0.0044 high
ENSG00000184363 PKP3 LAML 0.028 low
ENSG00000184363 PKP3 GBM 0.029 high
ENSG00000184363 PKP3 SKCM 0.0026 high
ENSG00000184363 PKP3 CESC 0.041 high
ENSG00000184363 PKP3 LIHC 0.0062 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency