Ensembl ID ENSG00000184357 Gene ID 3009 Accession 4719
Gene Symbol H1-5 Alias H1;H1B;H1.5;H1F5;H1s-3;HIST1H1B Full Name H1.5 linker histone, cluster member
Position 6 : 27866792 - 27867588 Length 797 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]

ENSG00000184357 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000184357 2.99 1.46e-11 KIRC
ENSG00000184357 1.76 3.26e-13 HNSC
ENSG00000184357 3.26 1.92e-45 BRCA
ENSG00000184357 3.94 8.74e-21 COAD
ENSG00000184357 3.40 2.27e-30 LUSC
ENSG00000184357 2.53 2.59e-12 PRAD
ENSG00000184357 3.09 2.94e-15 LIHC
ENSG00000184357 4.28 1.82e-24 UCEC
ENSG00000184357 5.19 8.42e-30 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000184357 tumor 10616730
ENSG00000184357 brain tumors 11342692
ENSG00000184357 AML 17451600
ENSG00000184357 pulmonary neuroendocrine tumors 23416030
ENSG00000184357 prostatic cancer 25130394
ENSG00000184357 tumour 26171933
ENSG00000184357 breast cancer 27406387
ENSG00000184357 cervical cancer 28554813
ENSG00000184357 cancers 31307224
ENSG00000184357 tumors 31794600
ENSG00000184357 tumor 9458372
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000184357 SARC 0.01 high
ENSG00000184357 STAD 0.0015 low
ENSG00000184357 PAAD 0.0073 high
ENSG00000184357 UCEC 0.029 low
ENSG00000184357 LUSC 0.022 high
ENSG00000184357 HNSC 0.023 high
ENSG00000184357 READ 0.0034 low
ENSG00000184357 KIRP 0.0075 high
ENSG00000184357 KICH 0.00026 high
ENSG00000184357 THYM 0.015 low
ENSG00000184357 UCS 0.013 low
ENSG00000184357 ESCA 0.0012 high
ENSG00000184357 OV 0.036 low
ENSG00000184357 DLBC 0.034 low
ENSG00000184357 SKCM 0.0049 high
ENSG00000184357 CESC 0.00027 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000184357 ESCA Del 1.504912 0.119445 0.395412 0.266304
ENSG00000184357 SKCM Amp 2.227198 0.168055 0.749187 0.517711
ENSG00000184357 LIHC Amp 0.829634 0.115651 0.744366 0.397297
ENSG00000184357 BLCA Amp 1.282381 0.186004 0.497901 0.284314
ENSG00000184357 UVM Amp 2.411362 0.267714 1.169068 0.537500
ENSG00000184357 OV Amp 1.251533 0.349078 0.696540 0.455959