Ensembl ID ENSG00000183665 Gene ID 55039 Accession 26091
Gene Symbol TRMT12 Alias TYW2;TRM12 Full Name tRNA methyltransferase 12 homolog
Position 8 : 124450820 - 124453026 Length 2207 bases Strand Plus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]

ENSG00000183665 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000183665 TRMT12 -0.5 1.99e-33 KIRC
ENSG00000183665 TRMT12 0.78 1.82e-31 BRCA
ENSG00000183665 TRMT12 0.64 1.57e-16 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000183665 TRMT12 breast cancer 17440925
ENSG00000183665 TRMT12 breast cancer 22761755
ENSG00000183665 TRMT12 breast cancer 31564910
ENSG00000183665 TRMT12 cancers 31957540
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000183665 TRMT12 SARC 0.007 high
ENSG00000183665 TRMT12 STAD 0.044 low
ENSG00000183665 TRMT12 CHOL 0.04 low
ENSG00000183665 TRMT12 UVM 0.037 high
ENSG00000183665 TRMT12 UCEC 0.012 high
ENSG00000183665 TRMT12 ACC 0.0062 high
ENSG00000183665 TRMT12 KICH 0.042 high
ENSG00000183665 TRMT12 LUAD 0.031 high
ENSG00000183665 TRMT12 PCPG 0.013 low
ENSG00000183665 TRMT12 THYM 0.016 low
ENSG00000183665 TRMT12 BRCA 0.012 high
ENSG00000183665 TRMT12 COAD 0.02 high
ENSG00000183665 TRMT12 DLBC 0.001 low
ENSG00000183665 TRMT12 KIRC 0.00019 low
ENSG00000183665 TRMT12 PRAD 0.04 high
ENSG00000183665 TRMT12 BLCA 0.016 low
ENSG00000183665 TRMT12 GBM 0.0052 low
ENSG00000183665 TRMT12 SKCM 0.0022 high
ENSG00000183665 TRMT12 LIHC 0.00029 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000183665 TRMT12 LUSC Amp 6.890628 0.343111 0.563586 0.682635
ENSG00000183665 TRMT12 LUAD Amp 10.739160 0.285761 0.651241 0.604651
ENSG00000183665 TRMT12 LGG Amp 14.970717 0.199785 0.766279 0.194932
ENSG00000183665 TRMT12 CESC Amp 2.128541 0.183231 0.637400 0.396610
ENSG00000183665 TRMT12 READ Amp 3.693051 0.257201 0.812105 0.654545
ENSG00000183665 TRMT12 COAD Amp 8.699348 0.193509 0.804245 0.572062
ENSG00000183665 TRMT12 PAAD Amp 4.438720 0.196912 0.508116 0.369565
ENSG00000183665 TRMT12 ESCA Amp 11.126554 0.705652 0.813101 0.744565
ENSG00000183665 TRMT12 SKCM Amp 3.584538 0.205295 0.778179 0.517711
ENSG00000183665 TRMT12 HNSC Amp 10.605760 0.285911 0.617171 0.733716
ENSG00000183665 TRMT12 LIHC Amp 18.834685 0.410111 1.188586 0.624324
ENSG00000183665 TRMT12 BLCA Amp 6.403529 0.319591 0.664946 0.610294
ENSG00000183665 TRMT12 BRCA Amp 51.525110 0.557954 1.080534 0.617593
ENSG00000183665 TRMT12 STAD Amp 8.347373 0.300431 0.643039 0.668934
ENSG00000183665 TRMT12 PRAD Amp 3.681429 0.086356 0.739708 0.306911
ENSG00000183665 TRMT12 UCEC Amp 5.537161 0.190285 0.833512 0.352505
ENSG00000183665 TRMT12 UVM Amp 11.732583 0.663941 1.522242 0.762500
ENSG00000183665 TRMT12 OV Amp 104.931448 1.534491 1.273142 0.747841