Ensembl ID
ENSG00000183570
Gene ID
54039
Accession
8651
Gene Symbol
PCBP3
Alias
PCBP3OT;ALPHA-CP3;PCBP3-OT1
Full Name
poly(rC) binding protein 3
Position
21 : 45643694 - 45942454
Length
298761 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. The protein encoded by this gene lacks the nuclear localization signals found in other subfamily members. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017]
ENSG00000183570 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000183570
PCBP3
-1.0
2.16e-11
BRCA
ENSG00000183570
PCBP3
4.50
2.36e-22
PCPG
ENSG00000183570
PCBP3
-2.5
9.02e-18
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000183570
PCBP3
Pancreatic Cancer
30275197
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000183570
PCBP3
MESO
0.0035
low
show
ENSG00000183570
PCBP3
UVM
0.003
low
show
ENSG00000183570
PCBP3
PAAD
0.0011
low
show
ENSG00000183570
PCBP3
UCEC
0.00022
high
show
ENSG00000183570
PCBP3
THCA
0.016
high
show
ENSG00000183570
PCBP3
LUSC
0.03
high
show
ENSG00000183570
PCBP3
READ
0.00071
high
show
ENSG00000183570
PCBP3
KICH
0.042
high
show
ENSG00000183570
PCBP3
PCPG
0.0019
high
show
ENSG00000183570
PCBP3
THYM
0.00027
low
show
ENSG00000183570
PCBP3
BRCA
0.0068
high
show
ENSG00000183570
PCBP3
COAD
0.00079
high
show
ENSG00000183570
PCBP3
UCS
0.0053
high
show
ENSG00000183570
PCBP3
OV
0.0012
high
show
ENSG00000183570
PCBP3
PRAD
0.042
high
show
ENSG00000183570
PCBP3
TGCT
0.021
high
show
ENSG00000183570
PCBP3
BLCA
0.034
high
show
ENSG00000183570
PCBP3
LAML
0.00018
low
show
ENSG00000183570
PCBP3
LIHC
0.036
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000183570
PCBP3
LUSC
Del
0.629172
0.064181
0.360496
0.560878
ENSG00000183570
PCBP3
LAML
Amp
2.896252
0.091359
1.153172
0.062827
ENSG00000183570
PCBP3
READ
Del
1.269418
0.087924
0.469157
0.418182
ENSG00000183570
PCBP3
SARC
Del
1.583021
0.147021
0.465793
0.241245
ENSG00000183570
PCBP3
HNSC
Del
2.000164
0.068443
0.351723
0.390805
ENSG00000183570
PCBP3
STAD
Del
1.728042
0.075123
0.384720
0.433107
ENSG00000183570
PCBP3
OV
Del
1.366907
0.190165
0.560468
0.398964
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