Ensembl ID
ENSG00000183496
Gene ID
84206
Accession
25297
Gene Symbol
MEX3B
Alias
RKHD3;MEX-3B;RNF195
Full Name
mex-3 RNA binding family member B
Position
15 : 82041778 - 82046119
Length
4342 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012]
ENSG00000183496 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000183496
MEX3B
1.17
2.56e-25
KIRC
ENSG00000183496
MEX3B
1.50
3.59e-22
LUSC
ENSG00000183496
MEX3B
1.11
2.36e-21
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000183496
MEX3B
Cancer
29496759
ENSG00000183496
MEX3B
tumor
29674509
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000183496
MEX3B
MESO
0.00024
high
show
ENSG00000183496
MEX3B
STAD
0.013
high
show
ENSG00000183496
MEX3B
UVM
0.011
high
show
ENSG00000183496
MEX3B
THCA
0.016
high
show
ENSG00000183496
MEX3B
ACC
0.00011
high
show
ENSG00000183496
MEX3B
KIRP
0.0029
high
show
ENSG00000183496
MEX3B
THYM
0.016
low
show
ENSG00000183496
MEX3B
OV
0.038
high
show
ENSG00000183496
MEX3B
KIRC
0.00027
high
show
ENSG00000183496
MEX3B
PRAD
0.0079
low
show
ENSG00000183496
MEX3B
BLCA
0.001
high
show
ENSG00000183496
MEX3B
LAML
0.0054
low
show
ENSG00000183496
MEX3B
SKCM
0.014
high
show
ENSG00000183496
MEX3B
CESC
0.035
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000183496
MEX3B
SKCM
Amp
2.479960
0.175127
0.505736
0.313351
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