Ensembl ID
ENSG00000183258
Gene ID
51428
Accession
18674
Gene Symbol
DDX41
Alias
ABS;MPLPF
Full Name
DEAD-box helicase 41
Position
5 : 177511577 - 177516961
Length
5385 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD box protein family and interacts with several spliceosomal proteins. In addition, the encoded protein may recognize the bacterial second messengers cyclic di-GMP and cyclic di-AMP, resulting in the induction of genes involved in the innate immune response. [provided by RefSeq, Jan 2017]
ENSG00000183258 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000183258
DDX41
1.03
4.92e-46
KIRC
ENSG00000183258
DDX41
0.69
1.56e-46
BRCA
ENSG00000183258
DDX41
0.56
2.41e-12
KIRP
ENSG00000183258
DDX41
0.66
6.57e-20
LIHC
ENSG00000183258
DDX41
0.85
7.25e-18
UCEC
ENSG00000183258
DDX41
0.59
5.35e-19
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000183258
DDX41
tumours
12075003
ENSG00000183258
DDX41
breast cancer
19356240
ENSG00000183258
DDX41
cancer
20069054
ENSG00000183258
DDX41
prostate cancer
20160681
ENSG00000183258
DDX41
breast cancer
2211609
ENSG00000183258
DDX41
AML
22237025
ENSG00000183258
DDX41
tumor
2254668
ENSG00000183258
DDX41
papillary thyroid cancer
23050789
ENSG00000183258
DDX41
tumor
23318396
ENSG00000183258
DDX41
cancer
23509463
ENSG00000183258
DDX41
tumor
25920683
ENSG00000183258
DDX41
Cancer
25965566
ENSG00000183258
DDX41
AML
26693794
ENSG00000183258
DDX41
acute myeloid leukemia (AML)
26712909
ENSG00000183258
DDX41
cancer
26925418
ENSG00000183258
DDX41
cancer
26934647
ENSG00000183258
DDX41
cancers
27036224
ENSG00000183258
DDX41
tumor
27174803
ENSG00000183258
DDX41
acute myeloid leukemia (AML)
27210295
ENSG00000183258
DDX41
Familial AML
27248996
ENSG00000183258
DDX41
AML
27502187
ENSG00000183258
DDX41
colon cancer
28293423
ENSG00000183258
DDX41
tumors
28547672
ENSG00000183258
DDX41
AML
28642594
ENSG00000183258
DDX41
AML
28955657
ENSG00000183258
DDX41
tumor
29670473
ENSG00000183258
DDX41
tumor
29871919
ENSG00000183258
DDX41
tumor
29930723
ENSG00000183258
DDX41
cancer
30144193
ENSG00000183258
DDX41
Cancer
30791739
ENSG00000183258
DDX41
cancer
30909662
ENSG00000183258
DDX41
cancer
30963592
ENSG00000183258
DDX41
cancer
31240215
ENSG00000183258
DDX41
AMLs
31484648
ENSG00000183258
DDX41
endometrial cancer
31521546
ENSG00000183258
DDX41
cancer
31523712
ENSG00000183258
DDX41
tumor
31779709
ENSG00000183258
DDX41
breast cancer
3383282
ENSG00000183258
DDX41
tumors
9926915
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000183258
DDX41
STAD
0.019
high
show
ENSG00000183258
DDX41
UVM
0.015
high
show
ENSG00000183258
DDX41
PAAD
0.026
low
show
ENSG00000183258
DDX41
THCA
0.037
high
show
ENSG00000183258
DDX41
ACC
0.025
high
show
ENSG00000183258
DDX41
LGG
0.018
low
show
ENSG00000183258
DDX41
HNSC
0.013
high
show
ENSG00000183258
DDX41
LUAD
0.0086
high
show
ENSG00000183258
DDX41
BRCA
0.03
high
show
ENSG00000183258
DDX41
COAD
0.032
low
show
ENSG00000183258
DDX41
DLBC
0.041
low
show
ENSG00000183258
DDX41
KIRC
0.001
high
show
ENSG00000183258
DDX41
PRAD
0.044
low
show
ENSG00000183258
DDX41
GBM
0.027
high
show
ENSG00000183258
DDX41
SKCM
0.00031
high
show
ENSG00000183258
DDX41
LIHC
0.00033
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000183258
DDX41
LGG
Del
4.095460
0.068800
0.419539
0.111111
ENSG00000183258
DDX41
KIRP
Amp
0.969852
0.061208
0.634107
0.125000
ENSG00000183258
DDX41
ACC
Amp
1.739466
0.455962
1.265817
0.688889
ENSG00000183258
DDX41
SKCM
Del
2.011377
0.086730
0.481580
0.299728
ENSG00000183258
DDX41
HNSC
Del
0.946984
0.057244
0.388249
0.379310
ENSG00000183258
DDX41
LIHC
Amp
1.990663
0.146109
0.560398
0.356757
ENSG00000183258
DDX41
BLCA
Del
2.426385
0.104285
0.403817
0.485294
ENSG00000183258
DDX41
KIRC
Amp
59.407579
0.327773
0.552815
0.626894
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