Ensembl ID ENSG00000183207 Gene ID 10856 Accession 10475
Gene Symbol RUVBL2 Alias RVB2;TIH2;ECP51;TIP48;CGI-46;ECP-51;INO80J;REPTIN;TIP49B;TAP54-beta Full Name RuvB like AAA ATPase 2
Position 19 : 48993562 - 49015970 Length 22409 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008]

ENSG00000183207 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000183207 RUVBL2 0.46 2.50e-11 KIRC
ENSG00000183207 RUVBL2 0.98 6.80e-49 BRCA
ENSG00000183207 RUVBL2 1.03 1.79e-15 COAD
ENSG00000183207 RUVBL2 0.90 8.24e-26 LUSC
ENSG00000183207 RUVBL2 0.64 3.09e-12 KIRP
ENSG00000183207 RUVBL2 1.12 4.92e-16 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000183207 RUVBL2 tumour 10998447
ENSG00000183207 RUVBL2 cancer 17157868
ENSG00000183207 RUVBL2 tumor 17588333
ENSG00000183207 RUVBL2 tumors 17657734
ENSG00000183207 RUVBL2 tumor 22540023
ENSG00000183207 RUVBL2 cancers 24786788
ENSG00000183207 RUVBL2 prostate tumor 25609707
ENSG00000183207 RUVBL2 tumor 26253138
ENSG00000183207 RUVBL2 tumor 31572066
ENSG00000183207 RUVBL2 tumor 31623618
ENSG00000183207 RUVBL2 cancer 31750255
ENSG00000183207 RUVBL2 Lung Cancer 31883965
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000183207 RUVBL2 MESO 0.00042 high
ENSG00000183207 RUVBL2 SARC 0.00037 high
ENSG00000183207 RUVBL2 STAD 0.021 low
ENSG00000183207 RUVBL2 CHOL 0.026 high
ENSG00000183207 RUVBL2 UVM 0.0034 high
ENSG00000183207 RUVBL2 UCEC 0.039 low
ENSG00000183207 RUVBL2 LGG 0.00031 high
ENSG00000183207 RUVBL2 HNSC 0.0081 high
ENSG00000183207 RUVBL2 KIRP 0.013 high
ENSG00000183207 RUVBL2 KICH 0.015 high
ENSG00000183207 RUVBL2 LUAD 0.0011 high
ENSG00000183207 RUVBL2 ESCA 0.027 high
ENSG00000183207 RUVBL2 DLBC 0.021 low
ENSG00000183207 RUVBL2 KIRC 0.00075 high
ENSG00000183207 RUVBL2 TGCT 0.0069 low
ENSG00000183207 RUVBL2 SKCM 0.0084 high
ENSG00000183207 RUVBL2 CESC 0.013 low
ENSG00000183207 RUVBL2 LIHC 0.0012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000183207 RUVBL2 LUSC Del 3.634419 0.100485 0.365764 0.279441
ENSG00000183207 RUVBL2 LUAD Del 2.773388 0.074694 0.319328 0.370155
ENSG00000183207 RUVBL2 LGG Del 16.187960 0.135490 0.663961 0.500975
ENSG00000183207 RUVBL2 CESC Del 0.825678 0.069363 0.423208 0.118644
ENSG00000183207 RUVBL2 SARC Del 2.928609 0.177774 0.458704 0.330739
ENSG00000183207 RUVBL2 GBM Del 12.018597 0.137161 0.527476 0.168111
ENSG00000183207 RUVBL2 PAAD Del 0.902849 0.049425 0.294972 0.119565
ENSG00000183207 RUVBL2 UCEC Del 1.216761 0.054635 0.461731 0.115028
ENSG00000183207 RUVBL2 OV Del 13.520007 0.331527 0.577157 0.518135