Ensembl ID
ENSG00000182173
Gene ID
283989
Accession
27561
Gene Symbol
TSEN54
Alias
PCH4;PCH5;PCH2A;sen54;SEN54L
Full Name
tRNA splicing endonuclease subunit 54
Position
17 : 75516060 - 75524735
Length
8676 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs tRNA RBP type
Canonical_RBPs
Summary
This gene encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.[provided by RefSeq, Oct 2009]
ENSG00000182173 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000182173
TSEN54
1.26
4.26e-76
BRCA
ENSG00000182173
TSEN54
0.64
8.96e-13
COAD
ENSG00000182173
TSEN54
0.87
3.88e-26
LUSC
ENSG00000182173
TSEN54
1.03
4.81e-26
LIHC
ENSG00000182173
TSEN54
0.91
5.73e-18
UCEC
ENSG00000182173
TSEN54
0.79
5.89e-26
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000182173
TSEN54
SARC
0.032
high
show
ENSG00000182173
TSEN54
STAD
0.00011
low
show
ENSG00000182173
TSEN54
CHOL
0.039
low
show
ENSG00000182173
TSEN54
UVM
0.014
low
show
ENSG00000182173
TSEN54
UCEC
0.0049
high
show
ENSG00000182173
TSEN54
THCA
0.02
low
show
ENSG00000182173
TSEN54
LGG
0.0063
high
show
ENSG00000182173
TSEN54
LUSC
0.037
low
show
ENSG00000182173
TSEN54
HNSC
0.0021
low
show
ENSG00000182173
TSEN54
READ
0.0027
low
show
ENSG00000182173
TSEN54
THYM
0.04
low
show
ENSG00000182173
TSEN54
BRCA
0.0049
low
show
ENSG00000182173
TSEN54
KIRC
7e-04
high
show
ENSG00000182173
TSEN54
BLCA
0.00018
low
show
ENSG00000182173
TSEN54
CESC
0.0023
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000182173
TSEN54
LUSC
Amp
2.548085
0.250397
0.460984
0.471058
ENSG00000182173
TSEN54
LUAD
Amp
3.037386
0.170037
0.411065
0.498062
ENSG00000182173
TSEN54
LGG
Amp
4.107918
0.089248
0.644158
0.083821
ENSG00000182173
TSEN54
CESC
Amp
3.629103
0.229483
0.693772
0.237288
ENSG00000182173
TSEN54
UCS
Amp
2.781769
0.799614
0.939192
0.535714
ENSG00000182173
TSEN54
GBM
Amp
1.680774
0.085566
0.464948
0.142114
ENSG00000182173
TSEN54
PAAD
Del
3.747687
0.098262
0.356137
0.228261
ENSG00000182173
TSEN54
ESCA
Amp
1.711421
0.321840
0.545436
0.391304
ENSG00000182173
TSEN54
SKCM
Amp
6.023631
0.267982
0.567071
0.348774
ENSG00000182173
TSEN54
LIHC
Amp
8.209290
0.261581
0.659225
0.386486
ENSG00000182173
TSEN54
BLCA
Amp
2.032497
0.210640
0.463082
0.475490
ENSG00000182173
TSEN54
BRCA
Amp
24.826935
0.385319
0.664889
0.375926
ENSG00000182173
TSEN54
STAD
Amp
0.822027
0.134695
0.437315
0.217687
ENSG00000182173
TSEN54
UCEC
Amp
8.235356
0.225408
0.661090
0.189239
ENSG00000182173
TSEN54
UVM
Amp
0.739547
0.167808
0.818139
0.162500
ENSG00000182173
TSEN54
OV
Amp
1.928430
0.372140
0.568384
0.336788
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