Ensembl ID ENSG00000182154 Gene ID 64975 Accession 14492
Gene Symbol MRPL41 Alias BMRP;PIG3;mL41;MRPL27;RPML27;MRP-L27 Full Name mitochondrial ribosomal protein L41
Position 9 : 137551879 - 137552555 Length 677 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family. [provided by RefSeq, Jul 2008]

ENSG00000182154 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000182154 MRPL41 0.85 5.06e-18 BRCA
ENSG00000182154 MRPL41 1.25 1.41e-11 KICH
ENSG00000182154 MRPL41 1.22 1.72e-21 PRAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000182154 MRPL41 tumor 16024796
ENSG00000182154 MRPL41 breast cancer 24160266
ENSG00000182154 MRPL41 cancer 29531015
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000182154 MRPL41 MESO 0.0085 high
ENSG00000182154 MRPL41 STAD 0.04 low
ENSG00000182154 MRPL41 UVM 0.0042 high
ENSG00000182154 MRPL41 PAAD 0.0055 low
ENSG00000182154 MRPL41 UCEC 0.00027 low
ENSG00000182154 MRPL41 LGG 0.023 low
ENSG00000182154 MRPL41 LUSC 0.049 high
ENSG00000182154 MRPL41 UCS 0.0041 high
ENSG00000182154 MRPL41 OV 0.03 low
ENSG00000182154 MRPL41 BLCA 0.031 low
ENSG00000182154 MRPL41 LAML 0.00025 high
ENSG00000182154 MRPL41 GBM 0.004 high
ENSG00000182154 MRPL41 SKCM 0.0023 high
ENSG00000182154 MRPL41 CESC 0.012 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000182154 MRPL41 SARC Del 2.732170 0.173561 0.555769 0.233463
ENSG00000182154 MRPL41 BRCA Del 0.644086 0.062653 0.373350 0.265741
ENSG00000182154 MRPL41 STAD Amp 1.042485 0.142168 0.411513 0.276644
ENSG00000182154 MRPL41 OV Del 1.986313 0.202319 0.567212 0.523316