Ensembl ID ENSG00000182004 Gene ID 6635 Accession 11161
Gene Symbol SNRPE Alias SME;Sm-E;HYPT11;snRNP-E Full Name small nuclear ribonucleoprotein polypeptide E
Position 1 : 203861599 - 203871152 Length 9554 bases Strand Plus strand
Status Confidence Main interacting RNAssnRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is a core component of U small nuclear ribonucleoproteins, which are key components of the pre-mRNA processing spliceosome. The encoded protein plays a role in the 3' end processing of histone transcripts. This protein is one of the targets in the autoimmune disease systemic lupus erythematosus, and mutations in this gene have been associated with hypotrichosis. Several pseudogenes of this gene have been identified. [provided by RefSeq, Jun 2016]

ENSG00000182004 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000182004 SNRPE 0.41 8.31e-13 KIRC
ENSG00000182004 SNRPE 1.15 2.21e-71 BRCA
ENSG00000182004 SNRPE 0.77 1.05e-16 COAD
ENSG00000182004 SNRPE 1.33 2.84e-53 LUSC
ENSG00000182004 SNRPE 0.49 2.82e-11 PRAD
ENSG00000182004 SNRPE 1.17 8.54e-28 LIHC
ENSG00000182004 SNRPE 1.12 7.50e-39 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000182004 SNRPE cancer 18208561
ENSG00000182004 SNRPE tumor 21688285
ENSG00000182004 SNRPE cancer 22053771
ENSG00000182004 SNRPE prostate cancer 22740892
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000182004 SNRPE MESO 0.02 high
ENSG00000182004 SNRPE SARC 0.00019 high
ENSG00000182004 SNRPE PAAD 0.011 high
ENSG00000182004 SNRPE UCEC 0.0057 high
ENSG00000182004 SNRPE LGG 0.0023 high
ENSG00000182004 SNRPE LUSC 0.043 low
ENSG00000182004 SNRPE HNSC 0.0041 high
ENSG00000182004 SNRPE KICH 0.00097 high
ENSG00000182004 SNRPE LUAD 0.00012 high
ENSG00000182004 SNRPE PCPG 0.0099 high
ENSG00000182004 SNRPE UCS 0.029 low
ENSG00000182004 SNRPE ESCA 0.001 high
ENSG00000182004 SNRPE OV 0.00049 low
ENSG00000182004 SNRPE DLBC 0.017 low
ENSG00000182004 SNRPE KIRC 0.019 high
ENSG00000182004 SNRPE TGCT 0.012 low
ENSG00000182004 SNRPE BLCA 0.00016 low
ENSG00000182004 SNRPE SKCM 0.018 high
ENSG00000182004 SNRPE LIHC 0.005 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000182004 SNRPE LUAD Amp 2.307983 0.155738 0.509903 0.717054
ENSG00000182004 SNRPE LGG Amp 14.268905 0.192406 1.297760 0.077973
ENSG00000182004 SNRPE READ Amp 0.715534 0.123563 0.599637 0.296970
ENSG00000182004 SNRPE SARC Del 0.752250 0.122167 0.414807 0.249027
ENSG00000182004 SNRPE GBM Amp 36.959110 0.446793 1.110266 0.221837
ENSG00000182004 SNRPE SKCM Amp 3.492960 0.203066 0.709460 0.553134
ENSG00000182004 SNRPE LIHC Amp 5.609119 0.218105 0.863957 0.727027
ENSG00000182004 SNRPE DLBC Amp 1.969232 0.304799 0.569904 0.333333
ENSG00000182004 SNRPE BRCA Amp 14.233045 0.302803 0.804669 0.758333
ENSG00000182004 SNRPE UCEC Amp 2.495828 0.142342 0.837395 0.432282
ENSG00000182004 SNRPE OV Amp 1.008942 0.339899 0.665376 0.516408