Ensembl ID ENSG00000181722 Gene ID 26137 Accession 13503
Gene Symbol ZBTB20 Alias HOF;DPZF;PRIMS;ODA-8S;ZNF288 Full Name zinc finger and BTB domain containing 20
Position 3 : 114314500 - 115147292 Length 832793 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]

ENSG00000181722 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000181722 ZBTB20 tumour 21654638
ENSG00000181722 ZBTB20 tumor 21702992
ENSG00000181722 ZBTB20 gastric cancer 22037551
ENSG00000181722 ZBTB20 gastric cancer 23861218
ENSG00000181722 ZBTB20 non-small cell lung cancer 25311537
ENSG00000181722 ZBTB20 tumor 26893361
ENSG00000181722 ZBTB20 gastric cancer 27127881
ENSG00000181722 ZBTB20 tumor 27183310
ENSG00000181722 ZBTB20 tumor 27446912
ENSG00000181722 ZBTB20 esophageal cancer 27646774
ENSG00000181722 ZBTB20 gastric cancer 28170390
ENSG00000181722 ZBTB20 tumor 28319090
ENSG00000181722 ZBTB20 tumor 29795261
ENSG00000181722 ZBTB20 cancer 30099442
ENSG00000181722 ZBTB20 tumor 30400878
ENSG00000181722 ZBTB20 AML 31539138
ENSG00000181722 ZBTB20 gastric cancer 31556767
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000181722 ZBTB20 MESO 0.039 low
ENSG00000181722 ZBTB20 SARC 0.021 low
ENSG00000181722 ZBTB20 CHOL 0.00052 low
ENSG00000181722 ZBTB20 UCEC 0.0023 high
ENSG00000181722 ZBTB20 THCA 0.0061 high
ENSG00000181722 ZBTB20 ACC 0.018 high
ENSG00000181722 ZBTB20 LGG 0.014 low
ENSG00000181722 ZBTB20 HNSC 0.002 low
ENSG00000181722 ZBTB20 KICH 0.0025 high
ENSG00000181722 ZBTB20 BRCA 0.021 low
ENSG00000181722 ZBTB20 DLBC 0.01 low
ENSG00000181722 ZBTB20 LAML 0.0046 low
ENSG00000181722 ZBTB20 GBM 0.0042 low
ENSG00000181722 ZBTB20 CESC 0.012 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000181722 ZBTB20 PCPG Del 0.725019 0.058142 0.618029 0.580247
ENSG00000181722 ZBTB20 OV Amp 3.970549 0.427386 0.747446 0.566494