Ensembl ID ENSG00000181610 Gene ID 51649 Accession 14509
Gene Symbol MRPS23 Alias mS23;CGI-138;COXPD46;HSPC329;MRP-S23 Full Name mitochondrial ribosomal protein S23
Position 17 : 57834781 - 57850056 Length 15276 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. [provided by RefSeq, Jul 2008]

ENSG00000181610 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000181610 MRPS23 0.97 6.90e-48 BRCA
ENSG00000181610 MRPS23 1.04 1.58e-28 COAD
ENSG00000181610 MRPS23 0.68 4.85e-13 LUSC
ENSG00000181610 MRPS23 0.78 1.47e-20 LIHC
ENSG00000181610 MRPS23 0.74 6.28e-16 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000181610 MRPS23 tumor 17054779
ENSG00000181610 MRPS23 tumors 18500990
ENSG00000181610 MRPS23 luminal breast cancer 25151356
ENSG00000181610 MRPS23 tumor 29069745
ENSG00000181610 MRPS23 tumor 30094405
ENSG00000181610 MRPS23 breast cancer 31950385
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000181610 MRPS23 PAAD 0.0048 low
ENSG00000181610 MRPS23 UCEC 0.01 high
ENSG00000181610 MRPS23 THCA 0.0028 low
ENSG00000181610 MRPS23 LGG 0.035 low
ENSG00000181610 MRPS23 HNSC 0.0036 high
ENSG00000181610 MRPS23 KIRP 0.041 low
ENSG00000181610 MRPS23 KICH 0.0094 high
ENSG00000181610 MRPS23 PCPG 0.0053 high
ENSG00000181610 MRPS23 BRCA 0.01 high
ENSG00000181610 MRPS23 COAD 0.036 low
ENSG00000181610 MRPS23 UCS 0.044 low
ENSG00000181610 MRPS23 OV 0.0015 low
ENSG00000181610 MRPS23 KIRC 0.032 high
ENSG00000181610 MRPS23 PRAD 0.049 high
ENSG00000181610 MRPS23 LAML 0.0036 high
ENSG00000181610 MRPS23 SKCM 0.011 low
ENSG00000181610 MRPS23 LIHC 0.00019 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000181610 MRPS23 LGG Amp 1.895220 0.061374 0.572466 0.070175
ENSG00000181610 MRPS23 PAAD Del 7.049668 0.139450 0.385841 0.255435
ENSG00000181610 MRPS23 SKCM Amp 3.831639 0.212534 0.549032 0.318801
ENSG00000181610 MRPS23 LIHC Amp 1.580565 0.136281 0.615228 0.332432
ENSG00000181610 MRPS23 BLCA Amp 0.691887 0.163118 0.480801 0.424020
ENSG00000181610 MRPS23 BRCA Amp 31.485456 0.431509 0.788209 0.352778
ENSG00000181610 MRPS23 UCEC Amp 0.710495 0.102952 0.554039 0.126160