Ensembl ID ENSG00000179409 Gene ID 50628 Accession 15717
Gene Symbol GEMIN4 Alias p97;HC56;HCAP1;HHRF-1;NEDMCR Full Name gem nuclear organelle associated protein 4
Position 17 : 744421 - 753999 Length 9579 bases Strand Minus strand
Status Confidence Main interacting RNAssnRNARBP type Non-canonical_RBPs
Summary The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

ENSG00000179409 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000179409 GEMIN4 bladder cancer 18381463
ENSG00000179409 GEMIN4 esophageal cancer 19138993
ENSG00000179409 GEMIN4 lung cancer 20721975
ENSG00000179409 GEMIN4 cancer 21692980
ENSG00000179409 GEMIN4 cancer 21811587
ENSG00000179409 GEMIN4 prostate cancer 22506892
ENSG00000179409 GEMIN4 breast cancer 23629745
ENSG00000179409 GEMIN4 cancer 25709475
ENSG00000179409 GEMIN4 gastric cancer 25784816
ENSG00000179409 GEMIN4 cancer 26203264
ENSG00000179409 GEMIN4 cancer 27019773
ENSG00000179409 GEMIN4 cancer 27107574
ENSG00000179409 GEMIN4 Lung Cancer 27669275
ENSG00000179409 GEMIN4 cancer 29138579
ENSG00000179409 GEMIN4 gastric cancer 29156806
ENSG00000179409 GEMIN4 cancer 30728672
ENSG00000179409 GEMIN4 tumor 31510013
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000179409 GEMIN4 MESO 0.035 high
ENSG00000179409 GEMIN4 SARC 0.0051 high
ENSG00000179409 GEMIN4 CHOL 0.015 high
ENSG00000179409 GEMIN4 PAAD 0.016 low
ENSG00000179409 GEMIN4 UCEC 0.009 low
ENSG00000179409 GEMIN4 THCA 0.02 high
ENSG00000179409 GEMIN4 ACC 0.018 high
ENSG00000179409 GEMIN4 LGG 0.025 high
ENSG00000179409 GEMIN4 HNSC 0.0058 low
ENSG00000179409 GEMIN4 READ 0.0028 low
ENSG00000179409 GEMIN4 KIRP 0.00018 high
ENSG00000179409 GEMIN4 KICH 0.0014 high
ENSG00000179409 GEMIN4 PCPG 0.0062 high
ENSG00000179409 GEMIN4 DLBC 0.037 low
ENSG00000179409 GEMIN4 KIRC 0.00064 low
ENSG00000179409 GEMIN4 PRAD 0.0028 high
ENSG00000179409 GEMIN4 TGCT 0.048 low
ENSG00000179409 GEMIN4 BLCA 0.0056 high
ENSG00000179409 GEMIN4 SKCM 0.00053 high
ENSG00000179409 GEMIN4 LIHC 0.005 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency