Ensembl ID
ENSG00000179151
Gene ID
80153
Accession
26114
Gene Symbol
EDC3
Alias
YJDC;LSM16;MRT50;YJEFN2;hYjeF_N2-15q23
Full Name
enhancer of mRNA decapping 3
Position
15 : 74630558 - 74696292
Length
65735 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017]
ENSG00000179151 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000179151
EDC3
0.25
1.48e-11
BRCA
ENSG00000179151
EDC3
0.72
1.80e-11
KICH
ENSG00000179151
EDC3
0.57
5.27e-20
LUSC
ENSG00000179151
EDC3
0.32
1.06e-12
PRAD
ENSG00000179151
EDC3
0.72
4.41e-30
LIHC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000179151
EDC3
LUSC
0.029
low
show
ENSG00000179151
EDC3
KIRP
0.0068
high
show
ENSG00000179151
EDC3
LUAD
0.019
high
show
ENSG00000179151
EDC3
PCPG
0.00052
high
show
ENSG00000179151
EDC3
UCS
0.047
low
show
ENSG00000179151
EDC3
ESCA
0.0032
low
show
ENSG00000179151
EDC3
OV
0.049
high
show
ENSG00000179151
EDC3
BLCA
0.017
high
show
ENSG00000179151
EDC3
SKCM
0.0032
high
show
ENSG00000179151
EDC3
LIHC
0.00015
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000179151
EDC3
SKCM
Amp
1.155576
0.135445
0.489906
0.291553
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