Ensembl ID ENSG00000178896 Gene ID 54512 Accession 18189
Gene Symbol EXOSC4 Alias SKI6;p12A;RRP41;Ski6p;RRP41A;Rrp41p;hRrp41p Full Name exosome component 4
Position 8 : 144078648 - 144080648 Length 2001 bases Strand Plus strand
Status Confidence Main interacting RNAsdiverseRBP type Canonical_RBPs
Summary Enables mRNA 3'-UTR AU-rich region binding activity. Involved in nucleic acid metabolic process and positive regulation of cell growth. Acts upstream of or within defense response to virus. Located in cytosol; nucleoplasm; and transcriptionally active chromatin. Part of exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000178896 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000178896 EXOSC4 1.51 6.73e-54 BRCA
ENSG00000178896 EXOSC4 1.38 4.50e-20 COAD
ENSG00000178896 EXOSC4 1.40 5.90e-47 LUSC
ENSG00000178896 EXOSC4 0.77 8.32e-12 PRAD
ENSG00000178896 EXOSC4 1.76 2.03e-27 UCEC
ENSG00000178896 EXOSC4 1.04 2.39e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000178896 EXOSC4 cancer 11511919
ENSG00000178896 EXOSC4 rectal cancer 15860437
ENSG00000178896 EXOSC4 colorectal cancer 16489531
ENSG00000178896 EXOSC4 cancer 20596649
ENSG00000178896 EXOSC4 pancreatic cancer 21357378
ENSG00000178896 EXOSC4 cancer 24763612
ENSG00000178896 EXOSC4 colorectal cancer 30155936
ENSG00000178896 EXOSC4 cancer 30340642
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000178896 EXOSC4 PAAD 0.049 low
ENSG00000178896 EXOSC4 UCEC 0.011 low
ENSG00000178896 EXOSC4 ACC 0.00087 high
ENSG00000178896 EXOSC4 LUSC 0.048 low
ENSG00000178896 EXOSC4 HNSC 0.023 high
ENSG00000178896 EXOSC4 KIRP 0.022 low
ENSG00000178896 EXOSC4 KICH 0.00042 high
ENSG00000178896 EXOSC4 LUAD 0.015 high
ENSG00000178896 EXOSC4 PCPG 0.016 low
ENSG00000178896 EXOSC4 UCS 0.0092 high
ENSG00000178896 EXOSC4 OV 0.00035 low
ENSG00000178896 EXOSC4 DLBC 0.041 low
ENSG00000178896 EXOSC4 KIRC 0.00011 high
ENSG00000178896 EXOSC4 PRAD 0.021 low
ENSG00000178896 EXOSC4 BLCA 0.046 low
ENSG00000178896 EXOSC4 LAML 0.0092 high
ENSG00000178896 EXOSC4 SKCM 0.004 high
ENSG00000178896 EXOSC4 CESC 0.01 high
ENSG00000178896 EXOSC4 LIHC 0.0037 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000178896 EXOSC4 LUSC Amp 7.921011 0.362522 0.582470 0.658683
ENSG00000178896 EXOSC4 LUAD Amp 6.051096 0.219906 0.624376 0.567829
ENSG00000178896 EXOSC4 LGG Amp 10.971340 0.160031 0.701236 0.177388
ENSG00000178896 EXOSC4 LGG Del 1.685039 0.049384 0.554899 0.052632
ENSG00000178896 EXOSC4 CESC Amp 2.979236 0.211316 0.634779 0.406780
ENSG00000178896 EXOSC4 READ Amp 4.075634 0.271686 0.840220 0.624242
ENSG00000178896 EXOSC4 COAD Amp 5.805710 0.153305 0.773983 0.556541
ENSG00000178896 EXOSC4 PAAD Amp 2.279447 0.134298 0.435665 0.353261
ENSG00000178896 EXOSC4 ESCA Amp 4.615119 0.459903 0.698802 0.663043
ENSG00000178896 EXOSC4 SKCM Amp 4.353501 0.226150 0.772184 0.523161
ENSG00000178896 EXOSC4 HNSC Amp 10.114269 0.279473 0.608046 0.720307
ENSG00000178896 EXOSC4 LIHC Amp 18.087328 0.398623 1.177663 0.600000
ENSG00000178896 EXOSC4 DLBC Amp 1.416472 0.258396 0.609102 0.291667
ENSG00000178896 EXOSC4 BLCA Amp 2.752051 0.232125 0.583150 0.585784
ENSG00000178896 EXOSC4 BRCA Amp 33.047798 0.441950 1.005951 0.572222
ENSG00000178896 EXOSC4 STAD Amp 3.622314 0.208292 0.585365 0.634921
ENSG00000178896 EXOSC4 PRAD Amp 1.261535 0.053984 0.694419 0.274390
ENSG00000178896 EXOSC4 UCEC Amp 1.598101 0.124563 0.729010 0.339518
ENSG00000178896 EXOSC4 UVM Amp 11.732583 0.660526 1.518657 0.762500
ENSG00000178896 EXOSC4 OV Amp 104.852680 1.533823 1.239709 0.754750