Ensembl ID ENSG00000178691 Gene ID 23512 Accession 17101
Gene Symbol SUZ12 Alias CHET9;IMMAS;JJAZ1 Full Name SUZ12 polycomb repressive complex 2 subunit
Position 17 : 31937007 - 32001038 Length 64032 bases Strand Plus strand
Status Confidence Main interacting RNAsncRNARBP type Non-canonical_RBPs
Summary This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 2009]

ENSG00000178691 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000178691 SUZ12 0.67 9.59e-16 LUSC
ENSG00000178691 SUZ12 0.65 1.42e-11 STAD
ENSG00000178691 SUZ12 0.51 3.52e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000178691 SUZ12 endometrial stromal tumors 11371647
ENSG00000178691 SUZ12 tumor 12850374
ENSG00000178691 SUZ12 tumors 16049311
ENSG00000178691 SUZ12 breast cancer 16766534
ENSG00000178691 SUZ12 AML 17172412
ENSG00000178691 SUZ12 tumor 17235569
ENSG00000178691 SUZ12 endometrial stromal tumors 17667554
ENSG00000178691 SUZ12 tumor 18077430
ENSG00000178691 SUZ12 endometrial cancer 18264096
ENSG00000178691 SUZ12 cancers 18447587
ENSG00000178691 SUZ12 cancer 18628979
ENSG00000178691 SUZ12 cervical cancer 18753137
ENSG00000178691 SUZ12 tumors 18800150
ENSG00000178691 SUZ12 tumor 18984978
ENSG00000178691 SUZ12 cancer 19158498
ENSG00000178691 SUZ12 breast cancer 19443447
ENSG00000178691 SUZ12 endometrial stromal tumors 19542872
ENSG00000178691 SUZ12 endometrial stromal tumors 20368795
ENSG00000178691 SUZ12 tumors 20558579
ENSG00000178691 SUZ12 tumours 20565864
ENSG00000178691 SUZ12 brain tumors 20920292
ENSG00000178691 SUZ12 tumor 21031597
ENSG00000178691 SUZ12 acute myeloid leukemia (AML) 21125401
ENSG00000178691 SUZ12 cancer 21131960
ENSG00000178691 SUZ12 tumors 21316079
ENSG00000178691 SUZ12 tumor 21447565
ENSG00000178691 SUZ12 liver cancer 21480320
ENSG00000178691 SUZ12 breast cancer 21536749
ENSG00000178691 SUZ12 tumors 21836477
ENSG00000178691 SUZ12 tumor 22237151
ENSG00000178691 SUZ12 cancer 22308277
ENSG00000178691 SUZ12 AML 22371884
ENSG00000178691 SUZ12 colorectal cancers 22467857
ENSG00000178691 SUZ12 tumor 22823977
ENSG00000178691 SUZ12 tumor 22870092
ENSG00000178691 SUZ12 epithelial ovarian cancer 22964433
ENSG00000178691 SUZ12 tumour 23101500
ENSG00000178691 SUZ12 uterine tumors 23211293
ENSG00000178691 SUZ12 breast cancer 23539298
ENSG00000178691 SUZ12 uterine tumors 23580382
ENSG00000178691 SUZ12 cancers 23588203
ENSG00000178691 SUZ12 tumor 23644490
ENSG00000178691 SUZ12 gastric cancer 23735840
ENSG00000178691 SUZ12 breast cancer 23845141
ENSG00000178691 SUZ12 cancer 23888369
ENSG00000178691 SUZ12 cancer 23888967
ENSG00000178691 SUZ12 tumors 23962719
ENSG00000178691 SUZ12 tumor 24019906
ENSG00000178691 SUZ12 tumour 24169343
ENSG00000178691 SUZ12 prostate cancer 24216986
ENSG00000178691 SUZ12 breast cancer 24434785
ENSG00000178691 SUZ12 non-small cell lung cancer 24633887
ENSG00000178691 SUZ12 endometrial stromal tumor 24750188
ENSG00000178691 SUZ12 tumor 24810056
ENSG00000178691 SUZ12 cancer 24966518
ENSG00000178691 SUZ12 tumours 25119042
ENSG00000178691 SUZ12 malignant peripheral nerve sheath tumors 25240281
ENSG00000178691 SUZ12 colorectal cancer 25243792
ENSG00000178691 SUZ12 tumor 25295075
ENSG00000178691 SUZ12 malignant peripheral nerve sheath tumors 25305755
ENSG00000178691 SUZ12 colorectal cancer 25326896
ENSG00000178691 SUZ12 cancer 25334066
ENSG00000178691 SUZ12 bladder cancer 25428918
ENSG00000178691 SUZ12 cancer 25653233
ENSG00000178691 SUZ12 gastric cancer 25672609
ENSG00000178691 SUZ12 tumors 25676695
ENSG00000178691 SUZ12 cancer 25699394
ENSG00000178691 SUZ12 lung cancers 25743773
ENSG00000178691 SUZ12 liver tumors 25855382
ENSG00000178691 SUZ12 liver tumors 25893293
ENSG00000178691 SUZ12 tumors 25966845
ENSG00000178691 SUZ12 cancer 26030458
ENSG00000178691 SUZ12 cancer 26176059
ENSG00000178691 SUZ12 cancer 26268246
ENSG00000178691 SUZ12 cancer 26298164
ENSG00000178691 SUZ12 tumor 26336870
ENSG00000178691 SUZ12 colon cancer 26407907
ENSG00000178691 SUZ12 bladder cancer 26516927
ENSG00000178691 SUZ12 colon cancer 26567139
ENSG00000178691 SUZ12 malignant peripheral nerve sheath tumors 26585554
ENSG00000178691 SUZ12 tumor 26837964
ENSG00000178691 SUZ12 endometrial stromal tumors 26838781
ENSG00000178691 SUZ12 tumors 26879382
ENSG00000178691 SUZ12 tumours 26990025
ENSG00000178691 SUZ12 tumor 27000413
ENSG00000178691 SUZ12 GBM 27135271
ENSG00000178691 SUZ12 sex cord tumor 27142911
ENSG00000178691 SUZ12 cancers 27191993
ENSG00000178691 SUZ12 Cancer 27277676
ENSG00000178691 SUZ12 liver cancer 27338022
ENSG00000178691 SUZ12 bladder cancers 27351382
ENSG00000178691 SUZ12 liver cancer 27367027
ENSG00000178691 SUZ12 tumors 27391317
ENSG00000178691 SUZ12 cancers 27471434
ENSG00000178691 SUZ12 tumors 27472460
ENSG00000178691 SUZ12 tumor 27486969
ENSG00000178691 SUZ12 DLBCLs 27550047
ENSG00000178691 SUZ12 tumour 27624887
ENSG00000178691 SUZ12 tumor 27845897
ENSG00000178691 SUZ12 prostate cancer 28042859
ENSG00000178691 SUZ12 tumour 28105421
ENSG00000178691 SUZ12 cancer 28125717
ENSG00000178691 SUZ12 tumour 28213670
ENSG00000178691 SUZ12 cancer 28228691
ENSG00000178691 SUZ12 tumours 28295484
ENSG00000178691 SUZ12 cancers 28322158
ENSG00000178691 SUZ12 tumors 28353387
ENSG00000178691 SUZ12 tumor 28412742
ENSG00000178691 SUZ12 bladder cancer 28515962
ENSG00000178691 SUZ12 Tumours 28587163
ENSG00000178691 SUZ12 malignant peripheral nerve sheath tumors 28752843
ENSG00000178691 SUZ12 tumor 28921929
ENSG00000178691 SUZ12 colorectal cancer 28966728
ENSG00000178691 SUZ12 tumours 29136690
ENSG00000178691 SUZ12 tumor 29394168
ENSG00000178691 SUZ12 tumor 29401683
ENSG00000178691 SUZ12 Breast Cancer 29471243
ENSG00000178691 SUZ12 tumors 29482987
ENSG00000178691 SUZ12 cancer 29504244
ENSG00000178691 SUZ12 cancer 29667751
ENSG00000178691 SUZ12 tumors 29849115
ENSG00000178691 SUZ12 tumor 30028354
ENSG00000178691 SUZ12 breast cancer 30100733
ENSG00000178691 SUZ12 tumors 30144186
ENSG00000178691 SUZ12 Cancer 30210606
ENSG00000178691 SUZ12 colorectal cancer 30266084
ENSG00000178691 SUZ12 malignant peripheral nerve sheath tumors 30291346
ENSG00000178691 SUZ12 malignant peripheral nerve sheath tumor 30402543
ENSG00000178691 SUZ12 cancer 30533569
ENSG00000178691 SUZ12 tumor 30791232
ENSG00000178691 SUZ12 Liver Cancer 31031847
ENSG00000178691 SUZ12 tumors 31107719
ENSG00000178691 SUZ12 cancer 31115583
ENSG00000178691 SUZ12 cancers 31234902
ENSG00000178691 SUZ12 tumor 31263101
ENSG00000178691 SUZ12 tumours 31357957
ENSG00000178691 SUZ12 cancer 31423228
ENSG00000178691 SUZ12 nerve sheath tumors 31462295
ENSG00000178691 SUZ12 tumor 31615558
ENSG00000178691 SUZ12 cancers 31786184
ENSG00000178691 SUZ12 HNSCC 31938073
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000178691 SUZ12 Endometrial Stromal Nodule gene_fusion 100.0% (28/28) 5 entries
ENSG00000178691 SUZ12 hemangioblastoma sequence_alteration 17.14% (6/35) 1 entry
ENSG00000178691 SUZ12 endometrial stromal sarcoma gene_fusion 86.55% (103/119) 9 entries
ENSG00000178691 SUZ12 leiomyoma gene_fusion 100.0% (4/4) 1 entry
ENSG00000178691 SUZ12 ovarian sex cord-stromal tumor gene_fusion 100.0% (24/24) 1 entry
ENSG00000178691 SUZ12 breast ductal adenocarcinoma missense_variant 2.086% (33/1582) 1 entry
ENSG00000178691 SUZ12 T-cell acute lymphoblastic leukemia stop_gained 2.621% (26/992) 2 entries
ENSG00000178691 SUZ12 skin melanoma sequence_alteration 0.9491% (11/1159) 2 entries
ENSG00000178691 SUZ12 bladder transitional cell carcinoma missense_variant 0.8969% (4/446) 2 entries
ENSG00000178691 SUZ12 rectal adenocarcinoma sequence_alteration 2.015% (11/546) 1 entry
ENSG00000178691 SUZ12 T-cell acute lymphoblastic leukemia frameshift_variant 2.621% (26/992) 4 entries
ENSG00000178691 SUZ12 colon adenocarcinoma sequence_alteration 1.04% (13/1250) 1 entry
ENSG00000178691 SUZ12 pancreatic ductal adenocarcinoma frameshift_variant 1.308% (22/1682) 1 entry
ENSG00000178691 SUZ12 colorectal adenocarcinoma missense_variant 1.993% (23/1154) 3 entries
ENSG00000178691 SUZ12 lung adenocarcinoma missense_variant 0.4267% (11/2578) 2 entries
ENSG00000178691 SUZ12 skin melanoma missense_variant 0.9491% (11/1159) 2 entries
ENSG00000178691 SUZ12 T-cell acute lymphoblastic leukemia missense_variant 2.621% (26/992) 3 entries
ENSG00000178691 SUZ12 esophageal squamous cell carcinoma missense_variant 0.8772% (6/684) 3 entries
ENSG00000178691 SUZ12 cecum adenocarcinoma missense_variant 1.901% (5/263) 2 entries
ENSG00000178691 SUZ12 acute myeloid leukemia missense_variant 0.7505% (8/1066) 1 entry
ENSG00000178691 SUZ12 myelodysplastic syndrome sequence_alteration 2.083% (3/144) 1 entry
ENSG00000178691 SUZ12 cecum adenocarcinoma stop_gained 1.901% (5/263) 2 entries
ENSG00000178691 SUZ12 colon adenocarcinoma missense_variant 1.04% (13/1250) 4 entries
ENSG00000178691 SUZ12 breast carcinoma missense_variant 0.7458% (11/1475) 1 entry
ENSG00000178691 SUZ12 basal cell carcinoma missense_variant 8.824% (6/68) 1 entry
ENSG00000178691 SUZ12 Endometrial Endometrioid Adenocarcinoma missense_variant 2.012% (13/646) 1 entry
ENSG00000178691 SUZ12 urothelial carcinoma missense_variant 3.488% (3/86) 1 entry
ENSG00000178691 SUZ12 clear cell renal carcinoma sequence_alteration 0.5054% (8/1583) 1 entry
ENSG00000178691 SUZ12 clear cell renal carcinoma missense_variant 0.5054% (8/1583) 2 entries
ENSG00000178691 SUZ12 pancreatic ductal adenocarcinoma missense_variant 1.308% (22/1682) 1 entry
ENSG00000178691 SUZ12 rectal adenocarcinoma missense_variant 2.015% (11/546) 5 entries
ENSG00000178691 SUZ12 hepatocellular carcinoma missense_variant 0.7114% (7/984) 1 entry
ENSG00000178691 SUZ12 T-cell acute lymphoblastic leukemia sequence_alteration 2.621% (26/992) 1 entry
ENSG00000178691 SUZ12 squamous cell lung carcinoma missense_variant 0.804% (8/995) 1 entry
ENSG00000178691 SUZ12 oral squamous cell carcinoma missense_variant 0.7634% (2/262) 2 entries
ENSG00000178691 SUZ12 central nervous system primitive neuroectodermal neoplasm sequence_alteration 0.6696% (3/448) 1 entry
ENSG00000178691 SUZ12 soft tissue sarcoma gene_fusion 0.678% (2/295) 1 entry
ENSG00000178691 SUZ12 anaplastic astrocytoma missense_variant 1.527% (2/131) 1 entry
ENSG00000178691 SUZ12 diffuse gastric adenocarcinoma sequence_alteration 1.22% (1/82) 1 entry
ENSG00000178691 SUZ12 malignant peripheral nerve sheath tumor sequence_alteration 15.38% (2/13) 1 entry
ENSG00000178691 SUZ12 Tonsillar Squamous Cell Carcinoma missense_variant 11.11% (1/9) 1 entry
ENSG00000178691 SUZ12 head and neck squamous cell carcinoma missense_variant 0.159% (1/629) 1 entry
ENSG00000178691 SUZ12 urothelial carcinoma frameshift_variant 3.488% (3/86) 1 entry
ENSG00000178691 SUZ12 Merkel cell skin cancer stop_gained 1.075% (1/93) 1 entry
ENSG00000178691 SUZ12 non-small cell lung carcinoma missense_variant 0.9524% (1/105) 1 entry
ENSG00000178691 SUZ12 breast ductal adenocarcinoma stop_gained 2.086% (33/1582) 1 entry
ENSG00000178691 SUZ12 Duodenal Adenocarcinoma missense_variant 5.882% (1/17) 1 entry
ENSG00000178691 SUZ12 colon adenocarcinoma frameshift_variant 1.04% (13/1250) 1 entry
ENSG00000178691 SUZ12 hairy cell leukemia frameshift_variant 4.762% (1/21) 1 entry
ENSG00000178691 SUZ12 brain glioblastoma missense_variant 0.165% (2/1212) 1 entry
ENSG00000178691 SUZ12 Gallbladder Adenocarcinoma missense_variant 0.7246% (1/138) 1 entry
ENSG00000178691 SUZ12 lung adenocarcinoma sequence_alteration 0.4267% (11/2578) 1 entry
ENSG00000178691 SUZ12 colon carcinoma missense_variant 12.5% (1/8) 1 entry
ENSG00000178691 SUZ12 Primary Pulmonary Diffuse Large B-Cell Lymphoma missense_variant 100.0% (1/1) 1 entry
ENSG00000178691 SUZ12 Mixed Lobular and Ductal Breast Carcinoma stop_gained 1.667% (1/60) 1 entry
ENSG00000178691 SUZ12 bladder transitional cell carcinoma frameshift_variant 0.8969% (4/446) 1 entry
ENSG00000178691 SUZ12 Anal Squamous Cell Carcinoma frameshift_variant 1.22% (1/82) 1 entry
ENSG00000178691 SUZ12 gliosarcoma frameshift_variant 9.091% (1/11) 1 entry
ENSG00000178691 SUZ12 polycythemia vera missense_variant 1.25% (1/80) 1 entry
ENSG00000178691 SUZ12 large cell lung carcinoma frameshift_variant 5.263% (1/19) 1 entry
ENSG00000178691 SUZ12 salivary gland squamous cell carcinoma missense_variant 50.0% (1/2) 1 entry
ENSG00000178691 SUZ12 colon adenocarcinoma stop_gained 1.04% (13/1250) 1 entry
ENSG00000178691 SUZ12 Olfactory Neuroblastoma missense_variant 33.33% (1/3) 1 entry
ENSG00000178691 SUZ12 bladder transitional cell carcinoma stop_gained 0.8969% (4/446) 1 entry
ENSG00000178691 SUZ12 bile duct adenocarcinoma missense_variant 0.2597% (1/385) 1 entry
ENSG00000178691 SUZ12 angiosarcoma missense_variant 2.128% (1/47) 1 entry
ENSG00000178691 SUZ12 lobular breast carcinoma missense_variant 1.299% (3/231) 1 entry
ENSG00000178691 SUZ12 pharyngeal squamous cell carcinoma missense_variant 1.235% (1/81) 1 entry
ENSG00000178691 SUZ12 colorectal adenocarcinoma stop_gained 1.993% (23/1154) 1 entry
ENSG00000178691 SUZ12 myelodysplastic syndrome missense_variant 2.083% (3/144) 1 entry
ENSG00000178691 SUZ12 T-cell acute lymphoblastic leukemia amino_acid_insertion 2.621% (26/992) 1 entry
ENSG00000178691 SUZ12 skin melanoma conservative_inframe_deletion 0.9491% (11/1159) 1 entry
ENSG00000178691 SUZ12 breast carcinoma gene_fusion 0.7458% (11/1475) 1 entry
ENSG00000178691 SUZ12 breast carcinoma stop_gained 0.7458% (11/1475) 1 entry
ENSG00000178691 SUZ12 urothelial carcinoma stop_gained 3.488% (3/86) 1 entry
ENSG00000178691 SUZ12 Dermatofibrosarcoma protuberans sequence_alteration 25.0% (1/4) 1 entry
ENSG00000178691 SUZ12 B-cell acute lymphoblastic leukemia missense_variant 1.852% (1/54) 1 entry
ENSG00000178691 SUZ12 osteosarcoma missense_variant 0.6579% (1/152) 1 entry
ENSG00000178691 SUZ12 solitary fibrous tumor sequence_alteration 3.448% (1/29) 1 entry
ENSG00000178691 SUZ12 brain glioblastoma sequence_alteration 0.165% (2/1212) 1 entry
ENSG00000178691 SUZ12 breast ductal adenocarcinoma conservative_inframe_deletion 2.086% (33/1582) 1 entry
ENSG00000178691 SUZ12 gastric intestinal type adenocarcinoma missense_variant 1.176% (1/85) 1 entry
ENSG00000178691 SUZ12 meningioma (disease) stop_gained 1.389% (1/72) 1 entry
ENSG00000178691 SUZ12 small cell lung carcinoma missense_variant 0.2242% (1/446) 1 entry
ENSG00000178691 SUZ12 glioma frameshift_variant 0.3339% (2/599) 1 entry
ENSG00000178691 SUZ12 chronic myelomonocytic leukemia missense_variant 1.205% (1/83) 1 entry
ENSG00000178691 SUZ12 malignant peripheral nerve sheath tumor stop_gained 15.38% (2/13) 1 entry
ENSG00000178691 SUZ12 basal cell carcinoma sequence_alteration 8.824% (6/68) 1 entry
ENSG00000178691 SUZ12 acute myeloid leukemia stop_gained 0.7505% (8/1066) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000178691 SUZ12 MESO 0.00042 high
ENSG00000178691 SUZ12 SARC 0.017 high
ENSG00000178691 SUZ12 UVM 0.033 high
ENSG00000178691 SUZ12 ACC 0.0012 high
ENSG00000178691 SUZ12 LUSC 0.047 low
ENSG00000178691 SUZ12 READ 0.015 low
ENSG00000178691 SUZ12 KIRP 0.012 high
ENSG00000178691 SUZ12 KICH 2e-04 high
ENSG00000178691 SUZ12 LUAD 0.031 high
ENSG00000178691 SUZ12 PCPG 0.05 high
ENSG00000178691 SUZ12 THYM 0.00076 low
ENSG00000178691 SUZ12 BRCA 0.033 high
ENSG00000178691 SUZ12 COAD 0.009 low
ENSG00000178691 SUZ12 UCS 0.017 low
ENSG00000178691 SUZ12 OV 0.011 high
ENSG00000178691 SUZ12 KIRC 0.00022 low
ENSG00000178691 SUZ12 BLCA 0.011 high
ENSG00000178691 SUZ12 LAML 0.0025 low
ENSG00000178691 SUZ12 LIHC 0.003 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000178691 SUZ12 LAML Del 1.418289 0.040812 0.584147 0.057592
ENSG00000178691 SUZ12 SARC Del 3.404998 0.187463 0.454942 0.299611
ENSG00000178691 SUZ12 PCPG Del 8.741030 0.176432 0.664140 0.259259
ENSG00000178691 SUZ12 BLCA Amp 2.012573 0.209981 0.520049 0.399510
ENSG00000178691 SUZ12 BRCA Del 2.741661 0.079695 0.426601 0.325926
ENSG00000178691 SUZ12 STAD Amp 1.092309 0.143909 0.419393 0.222222
ENSG00000178691 SUZ12 UCEC Del 2.055697 0.063874 0.583341 0.192950
ENSG00000178691 SUZ12 OV Del 1.268005 0.187921 0.645006 0.829016