Ensembl ID ENSG00000177600 Gene ID 6181 Accession 10377
Gene Symbol RPLP2 Alias P2;LP2;RPP2;D11S2243E Full Name ribosomal protein lateral stalk subunit P2
Position 11 : 809967 - 812876 Length 2910 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

ENSG00000177600 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000177600 RPLP2 0.89 7.39e-20 KIRC
ENSG00000177600 RPLP2 0.90 9.02e-11 KIRP
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000177600 RPLP2 cancer 20795553
ENSG00000177600 RPLP2 breast cancer 22966487
ENSG00000177600 RPLP2 breast cancers 28476032
ENSG00000177600 RPLP2 cancer 29221118
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000177600 RPLP2 CHOL 0.027 low
ENSG00000177600 RPLP2 UVM 0.0012 low
ENSG00000177600 RPLP2 THCA 0.016 low
ENSG00000177600 RPLP2 ACC 0.00021 high
ENSG00000177600 RPLP2 LGG 0.00025 low
ENSG00000177600 RPLP2 HNSC 0.033 high
ENSG00000177600 RPLP2 KIRP 0.0085 high
ENSG00000177600 RPLP2 PCPG 0.035 high
ENSG00000177600 RPLP2 THYM 0.013 low
ENSG00000177600 RPLP2 BRCA 0.0016 low
ENSG00000177600 RPLP2 COAD 0.032 high
ENSG00000177600 RPLP2 UCS 0.049 high
ENSG00000177600 RPLP2 BLCA 0.017 low
ENSG00000177600 RPLP2 LAML 0.023 high
ENSG00000177600 RPLP2 GBM 0.038 low
ENSG00000177600 RPLP2 LIHC 0.0013 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000177600 RPLP2 LUAD Del 2.575565 0.073016 0.301331 0.275194
ENSG00000177600 RPLP2 LGG Del 11.656919 0.113119 0.579771 0.204678
ENSG00000177600 RPLP2 CESC Del 0.916655 0.071565 0.481674 0.352542
ENSG00000177600 RPLP2 SARC Del 5.134172 0.219058 0.533779 0.424125
ENSG00000177600 RPLP2 GBM Del 2.184934 0.069049 0.466038 0.227036
ENSG00000177600 RPLP2 PAAD Del 1.079421 0.053544 0.329765 0.157609
ENSG00000177600 RPLP2 ESCA Del 1.672716 0.124152 0.369019 0.402174
ENSG00000177600 RPLP2 PCPG Del 1.180210 0.068835 0.622150 0.345679
ENSG00000177600 RPLP2 TGCT Del 0.643819 0.054133 0.383408 0.626667
ENSG00000177600 RPLP2 BLCA Del 2.849088 0.109857 0.437017 0.514706