Ensembl ID ENSG00000177374 Gene ID 3090 Accession 4909
Gene Symbol HIC1 Alias hic-1;ZBTB29;ZNF901 Full Name HIC ZBTB transcriptional repressor 1
Position 17 : 2054154 - 2063241 Length 9088 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2010]

ENSG00000177374 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000177374 HIC1 0.89 5.96e-16 KIRC
ENSG00000177374 HIC1 -0.6 3.80e-13 BRCA
ENSG00000177374 HIC1 -1.2 2.02e-19 LUSC
ENSG00000177374 HIC1 -2.5 8.12e-34 UCEC
ENSG00000177374 HIC1 -0.7 6.30e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000177374 HIC1 cancer 10072440
ENSG00000177374 HIC1 tumour 10360376
ENSG00000177374 HIC1 AML 10446989
ENSG00000177374 HIC1 tumors 10655551
ENSG00000177374 HIC1 tumor 11087658
ENSG00000177374 HIC1 ovarian tumors 11238060
ENSG00000177374 HIC1 colorectal cancer 11341745
ENSG00000177374 HIC1 tumor 11554746
ENSG00000177374 HIC1 tumor 12052894
ENSG00000177374 HIC1 tumors 12429618
ENSG00000177374 HIC1 cancer 12495446
ENSG00000177374 HIC1 cancer 12539045
ENSG00000177374 HIC1 tumors 12773202
ENSG00000177374 HIC1 tumor 12843452
ENSG00000177374 HIC1 tumors 12942643
ENSG00000177374 HIC1 tumor 14506157
ENSG00000177374 HIC1 tumours 14688019
ENSG00000177374 HIC1 tumors 14714493
ENSG00000177374 HIC1 tumor 15007385
ENSG00000177374 HIC1 cancer 15068392
ENSG00000177374 HIC1 tumor 15093138
ENSG00000177374 HIC1 tumors 15125225
ENSG00000177374 HIC1 tumors 15149548
ENSG00000177374 HIC1 cancer 15231840
ENSG00000177374 HIC1 tumor 15368319
ENSG00000177374 HIC1 cancer 15373830
ENSG00000177374 HIC1 tumors 15488761
ENSG00000177374 HIC1 cancer 15704048
ENSG00000177374 HIC1 tumors 15837543
ENSG00000177374 HIC1 ovarian cancer 16204069
ENSG00000177374 HIC1 tumor 16248899
ENSG00000177374 HIC1 Tumor 16269335
ENSG00000177374 HIC1 cancer 16301995
ENSG00000177374 HIC1 tumor 16386221
ENSG00000177374 HIC1 tumor 16398460
ENSG00000177374 HIC1 tumor 16412291
ENSG00000177374 HIC1 lung cancer 16435073
ENSG00000177374 HIC1 tumor 16596193
ENSG00000177374 HIC1 Cancer 16690027
ENSG00000177374 HIC1 cancer 16724116
ENSG00000177374 HIC1 tumour 16762039
ENSG00000177374 HIC1 tumor 16965951
ENSG00000177374 HIC1 tumor 17087942
ENSG00000177374 HIC1 tumors 17143621
ENSG00000177374 HIC1 tumor 17177027
ENSG00000177374 HIC1 tumor 17283066
ENSG00000177374 HIC1 tumor 17380894
ENSG00000177374 HIC1 tumor 17982487
ENSG00000177374 HIC1 TGCTs 18042148
ENSG00000177374 HIC1 tumors 18204436
ENSG00000177374 HIC1 tumour 18318772
ENSG00000177374 HIC1 tumour 18499731
ENSG00000177374 HIC1 Cancer 18723112
ENSG00000177374 HIC1 cancer 18751382
ENSG00000177374 HIC1 ovarian cancer 18757082
ENSG00000177374 HIC1 colon cancers 18832519
ENSG00000177374 HIC1 tumor 18974104
ENSG00000177374 HIC1 colorectal cancers 19002263
ENSG00000177374 HIC1 tumor 19015639
ENSG00000177374 HIC1 cervical cancers 19054549
ENSG00000177374 HIC1 breast cancer 19153073
ENSG00000177374 HIC1 cancer 19173036
ENSG00000177374 HIC1 cancers 19486893
ENSG00000177374 HIC1 cancer 19491197
ENSG00000177374 HIC1 cancer 19525223
ENSG00000177374 HIC1 lung cancer 19649206
ENSG00000177374 HIC1 tumor 19669207
ENSG00000177374 HIC1 Tumors 19686742
ENSG00000177374 HIC1 cervical cancer 19755648
ENSG00000177374 HIC1 tumor 19819984
ENSG00000177374 HIC1 Cancer 19822477
ENSG00000177374 HIC1 breast cancer 19946345
ENSG00000177374 HIC1 cancer 20129651
ENSG00000177374 HIC1 cancers 20154726
ENSG00000177374 HIC1 AML 20237504
ENSG00000177374 HIC1 tumor 20547755
ENSG00000177374 HIC1 Cancer 20591193
ENSG00000177374 HIC1 cancer 20634891
ENSG00000177374 HIC1 cancer 20676143
ENSG00000177374 HIC1 colorectal cancer 20682398
ENSG00000177374 HIC1 tumor 20687958
ENSG00000177374 HIC1 Cancer 20693263
ENSG00000177374 HIC1 rectal cancers 21037082
ENSG00000177374 HIC1 tumour 21104471
ENSG00000177374 HIC1 tumors 21253504
ENSG00000177374 HIC1 tumor 21277938
ENSG00000177374 HIC1 tumor 21297660
ENSG00000177374 HIC1 cancer 21309068
ENSG00000177374 HIC1 tumor 21318053
ENSG00000177374 HIC1 cancer 21518779
ENSG00000177374 HIC1 tumor 21533545
ENSG00000177374 HIC1 tumor 21566744
ENSG00000177374 HIC1 colon cancers 21738611
ENSG00000177374 HIC1 tumour 21868547
ENSG00000177374 HIC1 cancers 22016618
ENSG00000177374 HIC1 cancer 22064865
ENSG00000177374 HIC1 tumor 22136354
ENSG00000177374 HIC1 cancer 22140553
ENSG00000177374 HIC1 cancer 22184117
ENSG00000177374 HIC1 breast cancer 22194601
ENSG00000177374 HIC1 cancer 22315224
ENSG00000177374 HIC1 tumour 22327210
ENSG00000177374 HIC1 tumors 22363287
ENSG00000177374 HIC1 tumor 22510409
ENSG00000177374 HIC1 Tumor 22528874
ENSG00000177374 HIC1 tumors 22544915
ENSG00000177374 HIC1 pancreatic cancer 22552606
ENSG00000177374 HIC1 tumours 22596239
ENSG00000177374 HIC1 cancer 22662240
ENSG00000177374 HIC1 cancer 22704201
ENSG00000177374 HIC1 cervical cancer 22729741
ENSG00000177374 HIC1 tumor 22842566
ENSG00000177374 HIC1 breast cancer 22862837
ENSG00000177374 HIC1 tumor 22956503
ENSG00000177374 HIC1 cancer 23064502
ENSG00000177374 HIC1 Cancer 23178572
ENSG00000177374 HIC1 bone tumors 23199169
ENSG00000177374 HIC1 tumour 23251702
ENSG00000177374 HIC1 prostate cancer 23340301
ENSG00000177374 HIC1 cancer 23417673
ENSG00000177374 HIC1 cancer 23519122
ENSG00000177374 HIC1 tumor 23533570
ENSG00000177374 HIC1 cancer 23566242
ENSG00000177374 HIC1 HNSCC 23750501
ENSG00000177374 HIC1 gastric cancer 23765259
ENSG00000177374 HIC1 gastric cancer 23769968
ENSG00000177374 HIC1 tumor 23836983
ENSG00000177374 HIC1 tumor 23961262
ENSG00000177374 HIC1 pancreatic cancer 24063222
ENSG00000177374 HIC1 cancers 24067369
ENSG00000177374 HIC1 Cancer 24076391
ENSG00000177374 HIC1 Cancer 24086249
ENSG00000177374 HIC1 non-small-cell lung cancer 24133372
ENSG00000177374 HIC1 tumor 24154486
ENSG00000177374 HIC1 tumor 24252461
ENSG00000177374 HIC1 triple-negative breast cancer 24295734
ENSG00000177374 HIC1 cancers 24747176
ENSG00000177374 HIC1 tumors 24762809
ENSG00000177374 HIC1 tumor 24907396
ENSG00000177374 HIC1 AML 24944583
ENSG00000177374 HIC1 tumor 24992983
ENSG00000177374 HIC1 triple negative breast cancer 25068292
ENSG00000177374 HIC1 cancer 25245946
ENSG00000177374 HIC1 cancer 25309514
ENSG00000177374 HIC1 cancer 25486244
ENSG00000177374 HIC1 tumors 25841351
ENSG00000177374 HIC1 Tumor 25934696
ENSG00000177374 HIC1 cancer 26057381
ENSG00000177374 HIC1 laryngeal cancer 26137060
ENSG00000177374 HIC1 tumour 26163537
ENSG00000177374 HIC1 tumors 26198328
ENSG00000177374 HIC1 cancer 26208029
ENSG00000177374 HIC1 cancer 26243517
ENSG00000177374 HIC1 tumor 26510908
ENSG00000177374 HIC1 cancer 26619800
ENSG00000177374 HIC1 Tumor 26671036
ENSG00000177374 HIC1 tumors 26962412
ENSG00000177374 HIC1 tumours 27071708
ENSG00000177374 HIC1 cancer 27084425
ENSG00000177374 HIC1 pancreatic cancer 27085461
ENSG00000177374 HIC1 non-small cell lung cancer 27107418
ENSG00000177374 HIC1 oligodendroglial tumor 27367901
ENSG00000177374 HIC1 cervical cancer 27401842
ENSG00000177374 HIC1 tumor 27449031
ENSG00000177374 HIC1 tumor 27540971
ENSG00000177374 HIC1 COAD 27562343
ENSG00000177374 HIC1 tumour 27576364
ENSG00000177374 HIC1 cancer 27720955
ENSG00000177374 HIC1 tumor 27725726
ENSG00000177374 HIC1 tumor 27737204
ENSG00000177374 HIC1 tumor 27793057
ENSG00000177374 HIC1 cancer 27935866
ENSG00000177374 HIC1 breast cancer 28009350
ENSG00000177374 HIC1 tumour 28122587
ENSG00000177374 HIC1 tumor 28157158
ENSG00000177374 HIC1 AML 28187034
ENSG00000177374 HIC1 cancer 28327618
ENSG00000177374 HIC1 tumor 28451061
ENSG00000177374 HIC1 prostate cancer 28466555
ENSG00000177374 HIC1 tumor 28473981
ENSG00000177374 HIC1 tumor 28538185
ENSG00000177374 HIC1 metastatic colorectal cancer 28708932
ENSG00000177374 HIC1 cancer 28940471
ENSG00000177374 HIC1 tumors 28973968
ENSG00000177374 HIC1 cancer 29133799
ENSG00000177374 HIC1 tumor 29264523
ENSG00000177374 HIC1 tumor 29367758
ENSG00000177374 HIC1 tumors 29416701
ENSG00000177374 HIC1 cancer 29466736
ENSG00000177374 HIC1 cancer 29470558
ENSG00000177374 HIC1 cancers 29559730
ENSG00000177374 HIC1 tumor 29702530
ENSG00000177374 HIC1 tumour 29748642
ENSG00000177374 HIC1 tumor 29914167
ENSG00000177374 HIC1 tumor 29949994
ENSG00000177374 HIC1 cancer 29952116
ENSG00000177374 HIC1 tumor 30204129
ENSG00000177374 HIC1 Cancer 30249017
ENSG00000177374 HIC1 lung cancer 30312658
ENSG00000177374 HIC1 cancer 30417565
ENSG00000177374 HIC1 cancer 30496037
ENSG00000177374 HIC1 cancer 30710424
ENSG00000177374 HIC1 cancer 30710753
ENSG00000177374 HIC1 cancer 30925930
ENSG00000177374 HIC1 liver cancer 31108460
ENSG00000177374 HIC1 tumor 31405379
ENSG00000177374 HIC1 cancer 31477735
ENSG00000177374 HIC1 cancer 31513912
ENSG00000177374 HIC1 Breast Cancer 31680974
ENSG00000177374 HIC1 cancer 31795965
ENSG00000177374 HIC1 tumor 31923609
ENSG00000177374 HIC1 tumors 9135007
ENSG00000177374 HIC1 tumor 9671399
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000177374 HIC1 MESO 0.0058 high
ENSG00000177374 HIC1 STAD 0.019 high
ENSG00000177374 HIC1 PAAD 0.022 low
ENSG00000177374 HIC1 UCEC 0.0024 low
ENSG00000177374 HIC1 THCA 0.045 high
ENSG00000177374 HIC1 ACC 0.00093 high
ENSG00000177374 HIC1 LGG 0.0017 high
ENSG00000177374 HIC1 LUSC 0.024 high
ENSG00000177374 HIC1 HNSC 0.017 low
ENSG00000177374 HIC1 PCPG 0.015 low
ENSG00000177374 HIC1 THYM 0.00082 low
ENSG00000177374 HIC1 UCS 0.046 high
ENSG00000177374 HIC1 OV 0.015 high
ENSG00000177374 HIC1 KIRC 0.016 high
ENSG00000177374 HIC1 PRAD 0.023 low
ENSG00000177374 HIC1 TGCT 0.036 high
ENSG00000177374 HIC1 BLCA 0.023 high
ENSG00000177374 HIC1 GBM 0.039 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000177374 HIC1 LUAD Del 2.373449 0.071128 0.368129 0.546512
ENSG00000177374 HIC1 SARC Del 4.849993 0.214002 0.546674 0.350195
ENSG00000177374 HIC1 LIHC Del 6.203750 0.133722 0.645072 0.564865