Ensembl ID ENSG00000175792 Gene ID 8607 Accession 10474
Gene Symbol RUVBL1 Alias RVB1;TIH1;ECP54;TIP49;ECP-54;INO80H;NMP238;PONTIN;TIP49A;NMP238;Pontin52 Full Name RuvB like AAA ATPase 1
Position 3 : 128064778 - 128153914 Length 89137 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

ENSG00000175792 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000175792 RUVBL1 0.82 9.84e-21 HNSC
ENSG00000175792 RUVBL1 1.00 1.37e-11 BLCA
ENSG00000175792 RUVBL1 1.03 9.89e-70 BRCA
ENSG00000175792 RUVBL1 1.35 1.77e-63 COAD
ENSG00000175792 RUVBL1 1.33 5.90e-18 READ
ENSG00000175792 RUVBL1 1.54 7.18e-70 LUSC
ENSG00000175792 RUVBL1 0.68 3.62e-20 PRAD
ENSG00000175792 RUVBL1 1.34 6.70e-13 GBM
ENSG00000175792 RUVBL1 0.59 6.39e-14 LIHC
ENSG00000175792 RUVBL1 0.89 7.22e-17 STAD
ENSG00000175792 RUVBL1 0.90 1.32e-17 UCEC
ENSG00000175792 RUVBL1 0.78 1.07e-19 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000175792 RUVBL1 colon cancer 14675489
ENSG00000175792 RUVBL1 colon cancer 14695187
ENSG00000175792 RUVBL1 cancer 17157868
ENSG00000175792 RUVBL1 tumor 19507834
ENSG00000175792 RUVBL1 ovarian cancer 20635389
ENSG00000175792 RUVBL1 tumour 21617703
ENSG00000175792 RUVBL1 tumor 22540023
ENSG00000175792 RUVBL1 breast cancer 22886747
ENSG00000175792 RUVBL1 pancreatic cancer 24728183
ENSG00000175792 RUVBL1 breast cancer 24786788
ENSG00000175792 RUVBL1 tumour 25335079
ENSG00000175792 RUVBL1 tumor 26201077
ENSG00000175792 RUVBL1 cancer 26988609
ENSG00000175792 RUVBL1 tumor 27066592
ENSG00000175792 RUVBL1 AML 27250028
ENSG00000175792 RUVBL1 cancer 27722820
ENSG00000175792 RUVBL1 lung cancers 28028178
ENSG00000175792 RUVBL1 breast cancer 28341484
ENSG00000175792 RUVBL1 lung cancer 29545175
ENSG00000175792 RUVBL1 cancer 30559296
ENSG00000175792 RUVBL1 cancer 30640450
ENSG00000175792 RUVBL1 GBM 30864699
ENSG00000175792 RUVBL1 epithelial ovarian cancer 31083717
ENSG00000175792 RUVBL1 pancreatic cancer 31395079
ENSG00000175792 RUVBL1 tumor 31623618
ENSG00000175792 RUVBL1 tumor 31665067
ENSG00000175792 RUVBL1 cancer 31750255
ENSG00000175792 RUVBL1 Lung Cancer 31883965
ENSG00000175792 RUVBL1 tumors 9774387
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000175792 RUVBL1 SARC 0.003 high
ENSG00000175792 RUVBL1 PAAD 0.029 high
ENSG00000175792 RUVBL1 UCEC 0.028 low
ENSG00000175792 RUVBL1 ACC 0.011 high
ENSG00000175792 RUVBL1 LGG 0.0013 high
ENSG00000175792 RUVBL1 HNSC 0.027 high
ENSG00000175792 RUVBL1 READ 0.0046 low
ENSG00000175792 RUVBL1 KIRP 0.0017 low
ENSG00000175792 RUVBL1 KICH 0.02 high
ENSG00000175792 RUVBL1 LUAD 0.012 high
ENSG00000175792 RUVBL1 THYM 0.038 low
ENSG00000175792 RUVBL1 BRCA 0.039 low
ENSG00000175792 RUVBL1 COAD 0.0029 high
ENSG00000175792 RUVBL1 ESCA 0.043 high
ENSG00000175792 RUVBL1 DLBC 0.0012 low
ENSG00000175792 RUVBL1 KIRC 0.014 high
ENSG00000175792 RUVBL1 BLCA 0.038 high
ENSG00000175792 RUVBL1 SKCM 0.027 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000175792 RUVBL1 GBM Del 1.004317 0.055915 0.480234 0.093588
ENSG00000175792 RUVBL1 PRAD Amp 2.979298 0.076723 0.449309 0.150407