Ensembl ID ENSG00000175213 Gene ID 79797 Accession 20041
Gene Symbol ZNF408 Alias EVR6;RP72 Full Name zinc finger protein 408
Position 11 : 46701031 - 46705912 Length 4882 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP). [provided by RefSeq, Dec 2016]

ENSG00000175213 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000175213 ZNF408 0.54 1.26e-18 KIRC
ENSG00000175213 ZNF408 0.61 6.76e-31 BRCA
ENSG00000175213 ZNF408 0.79 8.38e-17 KICH
ENSG00000175213 ZNF408 0.74 6.45e-21 LUSC
ENSG00000175213 ZNF408 0.47 4.57e-11 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000175213 ZNF408 tumor 29872311
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000175213 ZNF408 MESO 0.028 high
ENSG00000175213 ZNF408 SARC 0.00029 low
ENSG00000175213 ZNF408 STAD 0.006 low
ENSG00000175213 ZNF408 UVM 0.045 low
ENSG00000175213 ZNF408 PAAD 0.0061 low
ENSG00000175213 ZNF408 UCEC 0.029 high
ENSG00000175213 ZNF408 ACC 0.00099 high
ENSG00000175213 ZNF408 LGG 0.0026 low
ENSG00000175213 ZNF408 READ 0.027 high
ENSG00000175213 ZNF408 LUAD 0.0058 high
ENSG00000175213 ZNF408 COAD 0.00096 high
ENSG00000175213 ZNF408 UCS 0.026 low
ENSG00000175213 ZNF408 BLCA 0.012 low
ENSG00000175213 ZNF408 LIHC 0.00014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000175213 ZNF408 PRAD Del 1.427315 0.081639 0.561039 0.065041