Ensembl ID ENSG00000174953 Gene ID 170506 Accession 14410
Gene Symbol DHX36 Alias G4R1;RHAU;DDX36;MLEL1 Full Name DEAH-box helicase 36
Position 3 : 154272546 - 154324487 Length 51942 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

ENSG00000174953 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000174953 DHX36 0.85 2.57e-26 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000174953 DHX36 colorectal cancer 18619730
ENSG00000174953 DHX36 breast cancer 21993297
ENSG00000174953 DHX36 colon cancer 27797375
ENSG00000174953 DHX36 cancer 30591072
ENSG00000174953 DHX36 cancer 31949493
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000174953 DHX36 MESO 0.03 high
ENSG00000174953 DHX36 SARC 0.0027 high
ENSG00000174953 DHX36 STAD 0.04 low
ENSG00000174953 DHX36 CHOL 0.049 low
ENSG00000174953 DHX36 UVM 0.01 low
ENSG00000174953 DHX36 PAAD 0.012 high
ENSG00000174953 DHX36 UCEC 0.0026 low
ENSG00000174953 DHX36 ACC 0.033 high
ENSG00000174953 DHX36 LGG 0.046 low
ENSG00000174953 DHX36 LUSC 0.0037 low
ENSG00000174953 DHX36 READ 0.03 low
ENSG00000174953 DHX36 UCS 0.023 high
ENSG00000174953 DHX36 KIRC 0.0051 low
ENSG00000174953 DHX36 PRAD 0.0054 high
ENSG00000174953 DHX36 GBM 0.005 low
ENSG00000174953 DHX36 SKCM 0.00018 low
ENSG00000174953 DHX36 LIHC 0.0087 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000174953 DHX36 LUSC Amp 52.678455 0.918126 0.973434 0.844311
ENSG00000174953 DHX36 CESC Amp 12.489141 0.415722 0.967279 0.711864
ENSG00000174953 DHX36 ESCA Amp 7.891305 0.590919 0.847730 0.608696
ENSG00000174953 DHX36 HNSC Amp 24.007488 0.443871 0.729007 0.683908
ENSG00000174953 DHX36 PCPG Del 0.840514 0.061484 0.630623 0.580247
ENSG00000174953 DHX36 BRCA Amp 0.828341 0.148047 0.515435 0.275926
ENSG00000174953 DHX36 STAD Amp 0.813742 0.134323 0.465138 0.292517
ENSG00000174953 DHX36 PRAD Amp 1.707258 0.060053 0.444252 0.142276
ENSG00000174953 DHX36 UCEC Amp 4.373453 0.173043 0.658896 0.235622
ENSG00000174953 DHX36 OV Amp 19.768201 0.692812 0.852423 0.702936