Ensembl ID ENSG00000174748 Gene ID 6138 Accession 10306
Gene Symbol RPL15 Alias L15;EC45;eL15;DBA12;RPL10;RPLY10;RPYL10 Full Name ribosomal protein L15
Position 3 : 23916591 - 23924374 Length 7784 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L15E family of ribosomal proteins and a component of the 60S subunit. This gene shares sequence similarity with the yeast ribosomal protein YL10 gene. Elevated expression of this gene has been observed in esophageal tumors and gastric cancer tissues, and deletion of this gene has been observed in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Mar 2017]

ENSG00000174748 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000174748 RPL15 -0.7 1.63e-20 HNSC
ENSG00000174748 RPL15 -0.4 2.84e-19 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000174748 RPL15 esophageal cancer 11223259
ENSG00000174748 RPL15 gastric cancer 16608517
ENSG00000174748 RPL15 skin cancer 16865251
ENSG00000174748 RPL15 cancer 19425501
ENSG00000174748 RPL15 gastric cancer 21612406
ENSG00000174748 RPL15 tumor 22491060
ENSG00000174748 RPL15 gastric cancer 23202957
ENSG00000174748 RPL15 prostate cancer 23262226
ENSG00000174748 RPL15 cancer 26039628
ENSG00000174748 RPL15 pancreatic cancer 26498693
ENSG00000174748 RPL15 cancer 27612557
ENSG00000174748 RPL15 colon cancer 31523176
ENSG00000174748 RPL15 cancer 31712650
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000174748 RPL15 SARC 0.00077 high
ENSG00000174748 RPL15 PAAD 0.03 low
ENSG00000174748 RPL15 UCEC 0.0033 low
ENSG00000174748 RPL15 ACC 0.0036 high
ENSG00000174748 RPL15 LUSC 0.015 low
ENSG00000174748 RPL15 READ 0.0061 low
ENSG00000174748 RPL15 KICH 0.039 high
ENSG00000174748 RPL15 LUAD 0.018 low
ENSG00000174748 RPL15 THYM 0.0097 low
ENSG00000174748 RPL15 BRCA 0.01 low
ENSG00000174748 RPL15 UCS 0.025 high
ENSG00000174748 RPL15 ESCA 0.013 high
ENSG00000174748 RPL15 BLCA 0.013 low
ENSG00000174748 RPL15 GBM 0.013 low
ENSG00000174748 RPL15 LIHC 0.0048 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000174748 RPL15 BLCA Amp 0.950769 0.173596 0.496019 0.355392
ENSG00000174748 RPL15 STAD Del 1.023025 0.065303 0.316404 0.306122
ENSG00000174748 RPL15 KIRC Del 51.146146 0.180852 0.516340 0.878788
ENSG00000174748 RPL15 OV Del 1.001813 0.181751 0.481095 0.317789