Ensembl ID ENSG00000174740 Gene ID 140886 Accession 13629
Gene Symbol PABPC5 Alias PABP5 Full Name poly(A) binding protein cytoplasmic 5
Position X : 91434595 - 91438584 Length 3990 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]

ENSG00000174740 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000174740 PABPC5 -1.4 1.24e-12 COAD
ENSG00000174740 PABPC5 -1.5 8.00e-17 LUSC
ENSG00000174740 PABPC5 -3.6 1.39e-46 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000174740 PABPC5 MESO 0.0034 low
ENSG00000174740 PABPC5 SARC 0.033 high
ENSG00000174740 PABPC5 STAD 0.0085 high
ENSG00000174740 PABPC5 PAAD 0.013 low
ENSG00000174740 PABPC5 THCA 0.037 low
ENSG00000174740 PABPC5 LUSC 0.038 high
ENSG00000174740 PABPC5 HNSC 0.014 low
ENSG00000174740 PABPC5 READ 0.028 high
ENSG00000174740 PABPC5 KIRP 0.0011 high
ENSG00000174740 PABPC5 LUAD 0.015 low
ENSG00000174740 PABPC5 UCS 0.019 low
ENSG00000174740 PABPC5 DLBC 0.012 high
ENSG00000174740 PABPC5 KIRC 0.0023 low
ENSG00000174740 PABPC5 PRAD 0.007 low
ENSG00000174740 PABPC5 BLCA 0.049 high
ENSG00000174740 PABPC5 LAML 0.014 low
ENSG00000174740 PABPC5 GBM 0.022 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency