Ensembl ID ENSG00000174177 Gene ID 348180 Accession 28005
Gene Symbol CTU2 Alias MFRG;NCS2;UPF0432;C16orf84 Full Name cytosolic thiouridylase subunit 2
Position 16 : 88706483 - 88715396 Length 8914 bases Strand Plus strand
Status Confidence Main interacting RNAstRNARBP type Non-canonical_RBPs
Summary This gene encodes a protein which is involved in the post-transcriptional modification of transfer RNAs (tRNAs). The encoded protein plays a role in thiolation of uridine residue present at the wobble position in a subset of tRNAs, resulting in enhanced codon reading accuracy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

ENSG00000174177 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000174177 CTU2 0.55 2.20e-15 KIRC
ENSG00000174177 CTU2 0.51 7.10e-11 BRCA
ENSG00000174177 CTU2 1.14 5.49e-24 COAD
ENSG00000174177 CTU2 0.99 1.24e-18 KICH
ENSG00000174177 CTU2 0.79 3.27e-20 LUSC
ENSG00000174177 CTU2 0.78 2.12e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000174177 CTU2 breast cancer 27811057
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000174177 CTU2 MESO 0.018 high
ENSG00000174177 CTU2 SARC 0.0018 high
ENSG00000174177 CTU2 STAD 0.035 low
ENSG00000174177 CTU2 UVM 0.0088 high
ENSG00000174177 CTU2 PAAD 0.001 low
ENSG00000174177 CTU2 ACC 0.012 high
ENSG00000174177 CTU2 LGG 0.0033 high
ENSG00000174177 CTU2 LUSC 0.037 high
ENSG00000174177 CTU2 KICH 0.00018 low
ENSG00000174177 CTU2 PCPG 0.013 low
ENSG00000174177 CTU2 THYM 0.00022 low
ENSG00000174177 CTU2 COAD 0.0037 high
ENSG00000174177 CTU2 OV 0.035 low
ENSG00000174177 CTU2 PRAD 0.048 high
ENSG00000174177 CTU2 SKCM 0.034 high
ENSG00000174177 CTU2 CESC 0.05 low
ENSG00000174177 CTU2 LIHC 0.0013 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000174177 CTU2 LUSC Del 0.815850 0.067206 0.370241 0.431138
ENSG00000174177 CTU2 LAML Del 1.466386 0.041379 0.631081 0.036649
ENSG00000174177 CTU2 LUAD Del 8.319271 0.115818 0.345605 0.356589
ENSG00000174177 CTU2 CESC Del 1.196823 0.077070 0.502068 0.196610
ENSG00000174177 CTU2 KIRP Del 2.345544 0.042479 0.659174 0.041667
ENSG00000174177 CTU2 UCS Del 1.709240 0.288062 0.599906 0.696429
ENSG00000174177 CTU2 GBM Del 0.709005 0.051975 0.429942 0.181976
ENSG00000174177 CTU2 SKCM Del 2.992494 0.099710 0.500160 0.359673
ENSG00000174177 CTU2 THCA Del 0.779408 0.009112 0.541374 0.012024
ENSG00000174177 CTU2 LIHC Del 1.789875 0.082808 0.584486 0.440541
ENSG00000174177 CTU2 TGCT Del 3.557254 0.116204 0.357904 0.460000
ENSG00000174177 CTU2 BRCA Del 5.077928 0.093028 0.524177 0.639815
ENSG00000174177 CTU2 PRAD Del 30.820050 0.253719 0.539520 0.408537
ENSG00000174177 CTU2 UCEC Del 4.394478 0.084161 0.630149 0.289425
ENSG00000174177 CTU2 MESO Del 2.321450 0.187908 0.547581 0.252874
ENSG00000174177 CTU2 OV Del 13.272254 0.329470 0.663471 0.765112