Ensembl ID ENSG00000173801 Gene ID 3728 Accession 6207
Gene Symbol JUP Alias PG;DP3;PDGB;PKGB;CTNNG;DPIII Full Name junction plakoglobin
Position 17 : 41754604 - 41786931 Length 32328 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]

ENSG00000173801 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000173801 -1.0 3.05e-35 KIRC
ENSG00000173801 0.69 9.15e-24 BRCA
ENSG00000173801 2.11 3.14e-64 LUSC
ENSG00000173801 0.84 1.01e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000173801 lung cancer 10830716
ENSG00000173801 TGCTs 11956097
ENSG00000173801 prostate cancer 14612934
ENSG00000173801 TGCTs 14670177
ENSG00000173801 tumours 15187990
ENSG00000173801 embryonal tumors 16115909
ENSG00000173801 tumours 18499731
ENSG00000173801 tumor 20049862
ENSG00000173801 tumor 20815920
ENSG00000173801 tumor 21042278
ENSG00000173801 AML 21138675
ENSG00000173801 breast cancer 2125988
ENSG00000173801 breast cancer 22098624
ENSG00000173801 tumor 23162466
ENSG00000173801 tumor 24006899
ENSG00000173801 breast cancer 27654269
ENSG00000173801 tumors 28123876
ENSG00000173801 tumor 28904855
ENSG00000173801 tumor 29377892
ENSG00000173801 tumor 29855376
ENSG00000173801 cancer 30171725
ENSG00000173801 tumors 30228356
ENSG00000173801 germ cell tumor 31087453
ENSG00000173801 tumor 31420988
ENSG00000173801 tumor 31425296
ENSG00000173801 AML 31455838
ENSG00000173801 tumor 9701362
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000173801 MESO 0.048 high
ENSG00000173801 PAAD 0.0027 high
ENSG00000173801 UCEC 0.0066 high
ENSG00000173801 READ 0.048 high
ENSG00000173801 LUAD 0.0019 high
ENSG00000173801 BRCA 0.0058 high
ENSG00000173801 UCS 0.0016 low
ENSG00000173801 OV 0.0048 high
ENSG00000173801 BLCA 0.017 high
ENSG00000173801 LAML 0.011 low
ENSG00000173801 GBM 0.0086 high
ENSG00000173801 SKCM 0.00037 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000173801 ACC Del 2.670266 0.169615 0.602498 0.288889
ENSG00000173801 ESCA Amp 13.260160 0.779804 1.098065 0.375000
ENSG00000173801 PCPG Del 3.857501 0.114948 0.654851 0.209877
ENSG00000173801 BRCA Del 5.485377 0.095133 0.423494 0.319444
ENSG00000173801 STAD Amp 30.385941 0.606212 1.028790 0.276644
ENSG00000173801 UCEC Del 2.974261 0.072311 0.561107 0.200371