Ensembl ID
ENSG00000172348
Gene ID
10231
Accession
3041
Gene Symbol
RCAN2
Alias
CSP2;RCN2;MCIP2;ZAKI4;ZAKI-4;DSCR1L1
Full Name
regulator of calcineurin 2
Position
6 : 46220736 - 46491972
Length
271237 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
ENSG00000172348 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000172348
-2.3
2.46e-28
HNSC
ENSG00000172348
-3.2
3.49e-25
BLCA
ENSG00000172348
-1.1
1.24e-43
BRCA
ENSG00000172348
-1.9
7.78e-38
COAD
ENSG00000172348
2.04
6.37e-26
KICH
ENSG00000172348
-1.9
6.63e-13
READ
ENSG00000172348
-1.9
1.07e-29
LUSC
ENSG00000172348
-1.1
4.74e-16
PRAD
ENSG00000172348
-2.1
1.76e-17
STAD
ENSG00000172348
-1.8
6.53e-17
UCEC
ENSG00000172348
-3.0
2.23e-14
ESCA
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000172348
cancer
27526107
ENSG00000172348
tumour
30307052
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000172348
STAD
0.044
high
show
ENSG00000172348
UVM
0.012
high
show
ENSG00000172348
PAAD
0.00031
low
show
ENSG00000172348
ACC
0.033
low
show
ENSG00000172348
LUSC
0.006
high
show
ENSG00000172348
READ
0.0098
high
show
ENSG00000172348
KIRP
0.035
low
show
ENSG00000172348
KICH
0.013
high
show
ENSG00000172348
LUAD
0.00022
low
show
ENSG00000172348
PCPG
0.003
high
show
ENSG00000172348
THYM
0.019
low
show
ENSG00000172348
DLBC
0.031
low
show
ENSG00000172348
BLCA
0.025
high
show
ENSG00000172348
LAML
0.015
high
show
ENSG00000172348
GBM
0.0083
high
show
ENSG00000172348
SKCM
0.0043
low
show
ENSG00000172348
LIHC
0.0023
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000172348
LUAD
Amp
0.795042
0.119425
0.475434
0.356589
ENSG00000172348
ESCA
Amp
1.366624
0.302279
0.662468
0.309783
ENSG00000172348
LIHC
Amp
0.933876
0.118672
0.757666
0.386486
ENSG00000172348
STAD
Amp
3.313829
0.201078
0.564330
0.258503
ENSG00000172348
UVM
Amp
0.686695
0.163156
1.056952
0.462500
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