Ensembl ID ENSG00000172183 Gene ID 3669 Accession 6130
Gene Symbol ISG20 Alias CD25;HEM45 Full Name interferon stimulated exonuclease gene 20
Position 15 : 88635670 - 88656483 Length 20814 bases Strand Plus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary Enables 3'-5' exonuclease activity and RNA binding activity. Involved in defense response to virus; negative regulation of viral genome replication; and nucleobase-containing compound catabolic process. Located in cytoplasm and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000172183 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000172183 ISG20 2.35 3.54e-91 KIRC
ENSG00000172183 ISG20 1.18 1.27e-28 BRCA
ENSG00000172183 ISG20 1.74 6.91e-23 KIRP
ENSG00000172183 ISG20 1.92 1.38e-24 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000172183 ISG20 cancer 11345586
ENSG00000172183 ISG20 tumor 19225562
ENSG00000172183 ISG20 tumours 21338529
ENSG00000172183 ISG20 GBM 25658639
ENSG00000172183 ISG20 tumor 29195126
ENSG00000172183 ISG20 tumour 29963243
ENSG00000172183 ISG20 tumor 30713788
ENSG00000172183 ISG20 tumor 31523389
ENSG00000172183 ISG20 tumour 9396823
ENSG00000172183 ISG20 tumor 9569007
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000172183 ISG20 MESO 0.0034 low
ENSG00000172183 ISG20 SARC 0.0021 low
ENSG00000172183 ISG20 STAD 0.019 low
ENSG00000172183 ISG20 HNSC 0.013 low
ENSG00000172183 ISG20 READ 0.00043 low
ENSG00000172183 ISG20 KIRP 0.025 high
ENSG00000172183 ISG20 LUAD 0.014 high
ENSG00000172183 ISG20 BRCA 0.0071 low
ENSG00000172183 ISG20 COAD 0.035 high
ENSG00000172183 ISG20 UCS 0.029 low
ENSG00000172183 ISG20 DLBC 0.032 high
ENSG00000172183 ISG20 BLCA 0.0077 low
ENSG00000172183 ISG20 CESC 8e-04 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000172183 ISG20 CESC Amp 1.595064 0.163303 0.545523 0.250847
ENSG00000172183 ISG20 SKCM Amp 3.549693 0.204249 0.542140 0.318801
ENSG00000172183 ISG20 BRCA Amp 1.269855 0.157156 0.565901 0.162963
ENSG00000172183 ISG20 STAD Amp 4.209120 0.221085 0.566590 0.213152