Ensembl ID
ENSG00000172172
Gene ID
28998
Accession
14278
Gene Symbol
MRPL13
Alias
L13;L13A;L13mt;RPL13;uL13m;RPML13
Full Name
mitochondrial ribosomal protein L13
Position
8 : 120380761 - 120445402
Length
64642 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs rRNA RBP type
Canonical_RBPs
Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
ENSG00000172172 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000172172
MRPL13
1.22
1.43e-57
BRCA
ENSG00000172172
MRPL13
1.24
3.21e-35
LUSC
ENSG00000172172
MRPL13
1.07
1.91e-21
UCEC
ENSG00000172172
MRPL13
0.88
3.66e-16
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000172172
MRPL13
tumor
28978646
ENSG00000172172
MRPL13
Breast cancer
30185896
ENSG00000172172
MRPL13
breast cancer
30881302
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000172172
MRPL13
MESO
0.01
high
show
ENSG00000172172
MRPL13
PAAD
0.0024
high
show
ENSG00000172172
MRPL13
UCEC
0.026
high
show
ENSG00000172172
MRPL13
LUSC
0.042
low
show
ENSG00000172172
MRPL13
HNSC
0.009
high
show
ENSG00000172172
MRPL13
READ
0.043
low
show
ENSG00000172172
MRPL13
KICH
3e-04
high
show
ENSG00000172172
MRPL13
THYM
0.013
low
show
ENSG00000172172
MRPL13
BRCA
1e-04
high
show
ENSG00000172172
MRPL13
ESCA
0.0026
high
show
ENSG00000172172
MRPL13
OV
0.026
low
show
ENSG00000172172
MRPL13
LAML
0.046
high
show
ENSG00000172172
MRPL13
SKCM
0.0032
low
show
ENSG00000172172
MRPL13
CESC
0.045
high
show
ENSG00000172172
MRPL13
LIHC
0.022
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000172172
MRPL13
LUSC
Amp
5.473298
0.315521
0.560015
0.666667
ENSG00000172172
MRPL13
LUAD
Amp
8.868546
0.260754
0.621522
0.593023
ENSG00000172172
MRPL13
LGG
Amp
13.949553
0.189279
0.741097
0.192982
ENSG00000172172
MRPL13
CESC
Amp
2.128541
0.183231
0.634178
0.400000
ENSG00000172172
MRPL13
READ
Amp
4.099013
0.272485
0.820244
0.654545
ENSG00000172172
MRPL13
COAD
Amp
6.103264
0.157411
0.783267
0.569845
ENSG00000172172
MRPL13
PAAD
Amp
1.250323
0.100203
0.400179
0.369565
ENSG00000172172
MRPL13
ESCA
Amp
5.989204
0.517101
0.730175
0.722826
ENSG00000172172
MRPL13
SKCM
Amp
2.923063
0.187391
0.777774
0.509537
ENSG00000172172
MRPL13
HNSC
Amp
8.966443
0.263506
0.607891
0.729885
ENSG00000172172
MRPL13
LIHC
Amp
18.576072
0.405446
1.199629
0.621622
ENSG00000172172
MRPL13
DLBC
Amp
0.878931
0.209017
0.635483
0.250000
ENSG00000172172
MRPL13
BLCA
Amp
3.879987
0.262711
0.633408
0.605392
ENSG00000172172
MRPL13
BRCA
Amp
47.728369
0.534909
1.078142
0.610185
ENSG00000172172
MRPL13
STAD
Amp
6.586624
0.269089
0.624988
0.662132
ENSG00000172172
MRPL13
PRAD
Amp
2.192152
0.066436
0.700495
0.306911
ENSG00000172172
MRPL13
UCEC
Amp
3.342070
0.156709
0.823746
0.348794
ENSG00000172172
MRPL13
UVM
Amp
12.051201
0.688775
1.538351
0.762500
ENSG00000172172
MRPL13
OV
Amp
85.516084
1.370456
1.189732
0.742660
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