Ensembl ID
ENSG00000171960
Gene ID
10465
Accession
14651
Gene Symbol
PPIH
Alias
CYPH;CYP-20;USA-CYP;SnuCyp-20
Full Name
peptidylprolyl isomerase H
Position
1 : 42658335 - 42676758
Length
18424 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Non-canonical_RBPs
Summary
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008]
ENSG00000171960 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000171960
PPIH
0.70
1.76e-31
BRCA
ENSG00000171960
PPIH
0.79
1.91e-15
COAD
ENSG00000171960
PPIH
1.02
1.79e-28
LUSC
ENSG00000171960
PPIH
1.01
1.45e-23
UCEC
ENSG00000171960
PPIH
0.65
1.93e-13
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000171960
PPIH
tumors
26284146
ENSG00000171960
PPIH
breast cancer
30906311
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000171960
PPIH
MESO
0.023
high
show
ENSG00000171960
PPIH
SARC
0.0011
high
show
ENSG00000171960
PPIH
STAD
0.0082
low
show
ENSG00000171960
PPIH
CHOL
0.014
low
show
ENSG00000171960
PPIH
PAAD
0.0065
high
show
ENSG00000171960
PPIH
HNSC
0.019
high
show
ENSG00000171960
PPIH
KICH
0.0029
high
show
ENSG00000171960
PPIH
PCPG
0.032
low
show
ENSG00000171960
PPIH
THYM
0.016
low
show
ENSG00000171960
PPIH
BRCA
0.0085
low
show
ENSG00000171960
PPIH
COAD
0.023
low
show
ENSG00000171960
PPIH
ESCA
0.05
high
show
ENSG00000171960
PPIH
OV
0.0056
low
show
ENSG00000171960
PPIH
DLBC
0.037
low
show
ENSG00000171960
PPIH
PRAD
0.02
high
show
ENSG00000171960
PPIH
LAML
0.00039
high
show
ENSG00000171960
PPIH
GBM
0.05
low
show
ENSG00000171960
PPIH
CESC
0.0045
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000171960
PPIH
CHOL
Del
0.852431
0.219537
0.555047
0.277778
ENSG00000171960
PPIH
LUAD
Amp
0.795042
0.119578
0.394303
0.277132
ENSG00000171960
PPIH
KIRP
Del
1.041839
0.030450
0.601455
0.138889
ENSG00000171960
PPIH
LIHC
Del
2.265246
0.089245
0.500566
0.286486
ENSG00000171960
PPIH
PCPG
Del
1.939026
0.084206
0.680908
0.641975
ENSG00000171960
PPIH
BLCA
Amp
1.335998
0.187888
0.545625
0.223039
ENSG00000171960
PPIH
UCEC
Amp
1.304503
0.118138
0.543559
0.128015
ENSG00000171960
PPIH
UVM
Del
1.063142
0.074432
0.810996
0.287500
ENSG00000171960
PPIH
OV
Amp
14.431424
0.617448
0.746503
0.480138
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