Ensembl ID ENSG00000171793 Gene ID 1503 Accession 2519
Gene Symbol CTPS1 Alias CTPS;GATD5;IMD24;GATD5A Full Name CTP synthase 1
Position 1 : 40979300 - 41012565 Length 33266 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

ENSG00000171793 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000171793 CTPS1 1.34 4.79e-55 BRCA
ENSG00000171793 CTPS1 1.17 1.78e-44 COAD
ENSG00000171793 CTPS1 1.24 1.22e-43 LUSC
ENSG00000171793 CTPS1 0.92 2.47e-17 STAD
ENSG00000171793 CTPS1 0.79 8.14e-15 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000171793 CTPS1 cancers 16820675
ENSG00000171793 CTPS1 cancer 22220215
ENSG00000171793 CTPS1 cancers 22989772
ENSG00000171793 CTPS1 basal-like breast cancer 23863842
ENSG00000171793 CTPS1 cancer 24477477
ENSG00000171793 CTPS1 tumors 27098510
ENSG00000171793 CTPS1 pancreatic cancer 28697344
ENSG00000171793 CTPS1 colorectal cancer 28847964
ENSG00000171793 CTPS1 cancers 29097181
ENSG00000171793 CTPS1 cancer 30184506
ENSG00000171793 CTPS1 tumors 30647855
ENSG00000171793 CTPS1 cancer 31240110
ENSG00000171793 CTPS1 cancers 31431504
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000171793 CTPS1 SARC 0.036 high
ENSG00000171793 CTPS1 STAD 0.0094 low
ENSG00000171793 CTPS1 UVM 0.0025 high
ENSG00000171793 CTPS1 PAAD 0.009 high
ENSG00000171793 CTPS1 UCEC 0.002 high
ENSG00000171793 CTPS1 ACC 0.00027 high
ENSG00000171793 CTPS1 LGG 0.00015 high
ENSG00000171793 CTPS1 READ 0.034 low
ENSG00000171793 CTPS1 LUAD 0.013 high
ENSG00000171793 CTPS1 PCPG 0.0019 high
ENSG00000171793 CTPS1 THYM 0.0064 low
ENSG00000171793 CTPS1 ESCA 0.019 high
ENSG00000171793 CTPS1 KIRC 0.044 low
ENSG00000171793 CTPS1 BLCA 0.015 high
ENSG00000171793 CTPS1 LAML 0.005 high
ENSG00000171793 CTPS1 SKCM 0.00034 high
ENSG00000171793 CTPS1 CESC 0.035 high
ENSG00000171793 CTPS1 LIHC 0.014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000171793 CTPS1 CHOL Del 1.366964 0.267655 0.616490 0.277778
ENSG00000171793 CTPS1 LUAD Amp 1.164591 0.129643 0.415599 0.269380
ENSG00000171793 CTPS1 KIRP Del 1.053942 0.030450 0.601841 0.138889
ENSG00000171793 CTPS1 PAAD Amp 0.651922 0.078788 0.593121 0.070652
ENSG00000171793 CTPS1 ESCA Amp 1.050533 0.283207 0.740548 0.201087
ENSG00000171793 CTPS1 LIHC Del 2.927340 0.097731 0.502500 0.289189
ENSG00000171793 CTPS1 PCPG Del 1.915138 0.083538 0.678590 0.635802
ENSG00000171793 CTPS1 BLCA Amp 3.782216 0.260347 0.653711 0.232843
ENSG00000171793 CTPS1 UCEC Amp 3.385883 0.157260 0.635843 0.133581
ENSG00000171793 CTPS1 UVM Del 1.628635 0.094732 0.809086 0.300000
ENSG00000171793 CTPS1 OV Amp 23.310268 0.739485 0.815014 0.502591