Ensembl ID
ENSG00000171530
Gene ID
6902
Accession
11579
Gene Symbol
TBCA
Alias
NA
Full Name
tubulin folding cofactor A
Position
5 : 77691166 - 77868780
Length
177615 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
ENSG00000171530 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000171530
TBCA
0.47
8.61e-15
KIRC
ENSG00000171530
TBCA
0.52
1.39e-21
BRCA
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000171530
TBCA
tumor
1008014
ENSG00000171530
TBCA
tumor
10837782
ENSG00000171530
TBCA
tumor
1184209
ENSG00000171530
TBCA
tumour
14562028
ENSG00000171530
TBCA
prostate cancer
15610384
ENSG00000171530
TBCA
breast cancer
16018801
ENSG00000171530
TBCA
GBM
16520389
ENSG00000171530
TBCA
Cancer
16570116
ENSG00000171530
TBCA
ovarian cancer
16968534
ENSG00000171530
TBCA
tumor
17074094
ENSG00000171530
TBCA
cancer
17352831
ENSG00000171530
TBCA
tumour
17395508
ENSG00000171530
TBCA
tumor
18809714
ENSG00000171530
TBCA
lung cancer
19159414
ENSG00000171530
TBCA
GBM
1922907
ENSG00000171530
TBCA
lung cancer
19258205
ENSG00000171530
TBCA
gastric cancer
19284299
ENSG00000171530
TBCA
breast cancer
19333782
ENSG00000171530
TBCA
cancer
19367561
ENSG00000171530
TBCA
tumour
19422380
ENSG00000171530
TBCA
cancer
19687109
ENSG00000171530
TBCA
cancer
19723309
ENSG00000171530
TBCA
tumours
19725989
ENSG00000171530
TBCA
tumors
20017942
ENSG00000171530
TBCA
ovarian cancer
20349782
ENSG00000171530
TBCA
tumors
21049016
ENSG00000171530
TBCA
cancer
21131166
ENSG00000171530
TBCA
tumors
21615919
ENSG00000171530
TBCA
bone cancer
21620878
ENSG00000171530
TBCA
tumor
21822917
ENSG00000171530
TBCA
tumor
21854615
ENSG00000171530
TBCA
cancer
21889998
ENSG00000171530
TBCA
cancer
22213595
ENSG00000171530
TBCA
prostate cancer
22290244
ENSG00000171530
TBCA
breast cancer
22419539
ENSG00000171530
TBCA
tumors
22431534
ENSG00000171530
TBCA
tumor
2428485
ENSG00000171530
TBCA
prostate cancer
24290046
ENSG00000171530
TBCA
cervical cancer
24372964
ENSG00000171530
TBCA
tumor
24604027
ENSG00000171530
TBCA
tumor
2464022
ENSG00000171530
TBCA
tumor
2479817
ENSG00000171530
TBCA
tumor
24801008
ENSG00000171530
TBCA
cancer
25329614
ENSG00000171530
TBCA
tumor
25343355
ENSG00000171530
TBCA
DLBCLs
25372838
ENSG00000171530
TBCA
Cancer
25395875
ENSG00000171530
TBCA
cancers
25957863
ENSG00000171530
TBCA
breast cancer
26258780
ENSG00000171530
TBCA
tumor
26401343
ENSG00000171530
TBCA
Cancer
26573805
ENSG00000171530
TBCA
tumor
26618181
ENSG00000171530
TBCA
breast cancer
26703694
ENSG00000171530
TBCA
tumors
26752261
ENSG00000171530
TBCA
primary cancer
26790428
ENSG00000171530
TBCA
Cancer
26872726
ENSG00000171530
TBCA
tumors
26880960
ENSG00000171530
TBCA
cancer
27035974
ENSG00000171530
TBCA
tumour
27237221
ENSG00000171530
TBCA
cancer
27275947
ENSG00000171530
TBCA
bone cancer
27577933
ENSG00000171530
TBCA
tumor
28428886
ENSG00000171530
TBCA
colorectal cancer
28634676
ENSG00000171530
TBCA
ovarian cancer
28857608
ENSG00000171530
TBCA
cancer
29210140
ENSG00000171530
TBCA
cancer
29211715
ENSG00000171530
TBCA
cancer
29614103
ENSG00000171530
TBCA
bone cancer
29615865
ENSG00000171530
TBCA
cancer
29661488
ENSG00000171530
TBCA
cancer
29998546
ENSG00000171530
TBCA
bone cancer
30079380
ENSG00000171530
TBCA
cancer
30285767
ENSG00000171530
TBCA
breast cancer
30314577
ENSG00000171530
TBCA
cancer
30322511
ENSG00000171530
TBCA
metastatic cancer
30487919
ENSG00000171530
TBCA
cancer
30497422
ENSG00000171530
TBCA
HNSCC
30526315
ENSG00000171530
TBCA
tumor
30643284
ENSG00000171530
TBCA
breast cancer
30684148
ENSG00000171530
TBCA
colorectal cancer
30806072
ENSG00000171530
TBCA
cancer
31076896
ENSG00000171530
TBCA
breast cancer
31178786
ENSG00000171530
TBCA
cancer
31214025
ENSG00000171530
TBCA
tumour
31461207
ENSG00000171530
TBCA
prostate cancer
31464649
ENSG00000171530
TBCA
tumors
31480307
ENSG00000171530
TBCA
breast cancer
31702413
ENSG00000171530
TBCA
AML
31755141
ENSG00000171530
TBCA
tumor
50348
ENSG00000171530
TBCA
tumour
6139301
ENSG00000171530
TBCA
lymphoid tumor
6586288
ENSG00000171530
TBCA
tumor
6674792
ENSG00000171530
TBCA
prostate cancer
8664166
ENSG00000171530
TBCA
uterine cancers
9584513
ENSG00000171530
TBCA
Cancer
PMC2838404
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000171530
TBCA
MESO
0.05
low
show
ENSG00000171530
TBCA
SARC
0.03
high
show
ENSG00000171530
TBCA
STAD
0.047
high
show
ENSG00000171530
TBCA
UVM
0.046
high
show
ENSG00000171530
TBCA
PAAD
0.014
low
show
ENSG00000171530
TBCA
UCEC
0.02
high
show
ENSG00000171530
TBCA
THCA
0.005
low
show
ENSG00000171530
TBCA
ACC
0.017
high
show
ENSG00000171530
TBCA
HNSC
0.018
high
show
ENSG00000171530
TBCA
KIRP
0.00055
high
show
ENSG00000171530
TBCA
LUAD
0.013
high
show
ENSG00000171530
TBCA
PCPG
0.0058
high
show
ENSG00000171530
TBCA
THYM
0.015
high
show
ENSG00000171530
TBCA
BRCA
0.023
high
show
ENSG00000171530
TBCA
ESCA
0.035
high
show
ENSG00000171530
TBCA
OV
0.049
low
show
ENSG00000171530
TBCA
BLCA
0.03
low
show
ENSG00000171530
TBCA
SKCM
0.0027
low
show
ENSG00000171530
TBCA
CESC
0.021
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000171530
TBCA
LUSC
Del
2.664263
0.090761
0.405876
0.776447
ENSG00000171530
TBCA
LUAD
Del
2.402531
0.071337
0.337355
0.416667
ENSG00000171530
TBCA
COAD
Del
1.157992
0.047531
0.379101
0.239468
ENSG00000171530
TBCA
UCS
Del
0.949427
0.222330
0.466152
0.500000
ENSG00000171530
TBCA
PAAD
Del
1.757893
0.066489
0.338281
0.184783
ENSG00000171530
TBCA
ESCA
Del
1.910229
0.131212
0.434360
0.603261
ENSG00000171530
TBCA
HNSC
Del
2.483550
0.072799
0.388825
0.419540
ENSG00000171530
TBCA
BLCA
Del
3.898791
0.122063
0.413470
0.504902
ENSG00000171530
TBCA
BRCA
Del
5.514096
0.095233
0.450878
0.273148
ENSG00000171530
TBCA
STAD
Del
5.625690
0.113666
0.392515
0.369615
ENSG00000171530
TBCA
PRAD
Del
10.804324
0.154256
0.542246
0.160569
ENSG00000171530
TBCA
UCEC
Del
5.880987
0.094606
0.500446
0.202226
ENSG00000171530
TBCA
OV
Del
71.284162
0.669598
0.674993
0.716753
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