Ensembl ID ENSG00000171530 Gene ID 6902 Accession 11579
Gene Symbol TBCA Alias NA Full Name tubulin folding cofactor A
Position 5 : 77691166 - 77868780 Length 177615 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

ENSG00000171530 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000171530 0.47 8.61e-15 KIRC
ENSG00000171530 0.52 1.39e-21 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000171530 tumor 1008014
ENSG00000171530 tumor 10837782
ENSG00000171530 tumor 1184209
ENSG00000171530 tumour 14562028
ENSG00000171530 prostate cancer 15610384
ENSG00000171530 breast cancer 16018801
ENSG00000171530 GBM 16520389
ENSG00000171530 Cancer 16570116
ENSG00000171530 ovarian cancer 16968534
ENSG00000171530 tumor 17074094
ENSG00000171530 cancer 17352831
ENSG00000171530 tumour 17395508
ENSG00000171530 tumor 18809714
ENSG00000171530 lung cancer 19159414
ENSG00000171530 GBM 1922907
ENSG00000171530 lung cancer 19258205
ENSG00000171530 gastric cancer 19284299
ENSG00000171530 breast cancer 19333782
ENSG00000171530 cancer 19367561
ENSG00000171530 tumour 19422380
ENSG00000171530 cancer 19687109
ENSG00000171530 cancer 19723309
ENSG00000171530 tumours 19725989
ENSG00000171530 tumors 20017942
ENSG00000171530 ovarian cancer 20349782
ENSG00000171530 tumors 21049016
ENSG00000171530 cancer 21131166
ENSG00000171530 tumors 21615919
ENSG00000171530 bone cancer 21620878
ENSG00000171530 tumor 21822917
ENSG00000171530 tumor 21854615
ENSG00000171530 cancer 21889998
ENSG00000171530 cancer 22213595
ENSG00000171530 prostate cancer 22290244
ENSG00000171530 breast cancer 22419539
ENSG00000171530 tumors 22431534
ENSG00000171530 tumor 2428485
ENSG00000171530 prostate cancer 24290046
ENSG00000171530 cervical cancer 24372964
ENSG00000171530 tumor 24604027
ENSG00000171530 tumor 2464022
ENSG00000171530 tumor 2479817
ENSG00000171530 tumor 24801008
ENSG00000171530 cancer 25329614
ENSG00000171530 tumor 25343355
ENSG00000171530 DLBCLs 25372838
ENSG00000171530 Cancer 25395875
ENSG00000171530 cancers 25957863
ENSG00000171530 breast cancer 26258780
ENSG00000171530 tumor 26401343
ENSG00000171530 Cancer 26573805
ENSG00000171530 tumor 26618181
ENSG00000171530 breast cancer 26703694
ENSG00000171530 tumors 26752261
ENSG00000171530 primary cancer 26790428
ENSG00000171530 Cancer 26872726
ENSG00000171530 tumors 26880960
ENSG00000171530 cancer 27035974
ENSG00000171530 tumour 27237221
ENSG00000171530 cancer 27275947
ENSG00000171530 bone cancer 27577933
ENSG00000171530 tumor 28428886
ENSG00000171530 colorectal cancer 28634676
ENSG00000171530 ovarian cancer 28857608
ENSG00000171530 cancer 29210140
ENSG00000171530 cancer 29211715
ENSG00000171530 cancer 29614103
ENSG00000171530 bone cancer 29615865
ENSG00000171530 cancer 29661488
ENSG00000171530 cancer 29998546
ENSG00000171530 bone cancer 30079380
ENSG00000171530 cancer 30285767
ENSG00000171530 breast cancer 30314577
ENSG00000171530 cancer 30322511
ENSG00000171530 metastatic cancer 30487919
ENSG00000171530 cancer 30497422
ENSG00000171530 HNSCC 30526315
ENSG00000171530 tumor 30643284
ENSG00000171530 breast cancer 30684148
ENSG00000171530 colorectal cancer 30806072
ENSG00000171530 cancer 31076896
ENSG00000171530 breast cancer 31178786
ENSG00000171530 cancer 31214025
ENSG00000171530 tumour 31461207
ENSG00000171530 prostate cancer 31464649
ENSG00000171530 tumors 31480307
ENSG00000171530 breast cancer 31702413
ENSG00000171530 AML 31755141
ENSG00000171530 tumor 50348
ENSG00000171530 tumour 6139301
ENSG00000171530 lymphoid tumor 6586288
ENSG00000171530 tumor 6674792
ENSG00000171530 prostate cancer 8664166
ENSG00000171530 uterine cancers 9584513
ENSG00000171530 Cancer PMC2838404
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000171530 MESO 0.05 low
ENSG00000171530 SARC 0.03 high
ENSG00000171530 STAD 0.047 high
ENSG00000171530 UVM 0.046 high
ENSG00000171530 PAAD 0.014 low
ENSG00000171530 UCEC 0.02 high
ENSG00000171530 THCA 0.005 low
ENSG00000171530 ACC 0.017 high
ENSG00000171530 HNSC 0.018 high
ENSG00000171530 KIRP 0.00055 high
ENSG00000171530 LUAD 0.013 high
ENSG00000171530 PCPG 0.0058 high
ENSG00000171530 THYM 0.015 high
ENSG00000171530 BRCA 0.023 high
ENSG00000171530 ESCA 0.035 high
ENSG00000171530 OV 0.049 low
ENSG00000171530 BLCA 0.03 low
ENSG00000171530 SKCM 0.0027 low
ENSG00000171530 CESC 0.021 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000171530 LUSC Del 2.664263 0.090761 0.405876 0.776447
ENSG00000171530 LUAD Del 2.402531 0.071337 0.337355 0.416667
ENSG00000171530 COAD Del 1.157992 0.047531 0.379101 0.239468
ENSG00000171530 UCS Del 0.949427 0.222330 0.466152 0.500000
ENSG00000171530 PAAD Del 1.757893 0.066489 0.338281 0.184783
ENSG00000171530 ESCA Del 1.910229 0.131212 0.434360 0.603261
ENSG00000171530 HNSC Del 2.483550 0.072799 0.388825 0.419540
ENSG00000171530 BLCA Del 3.898791 0.122063 0.413470 0.504902
ENSG00000171530 BRCA Del 5.514096 0.095233 0.450878 0.273148
ENSG00000171530 STAD Del 5.625690 0.113666 0.392515 0.369615
ENSG00000171530 PRAD Del 10.804324 0.154256 0.542246 0.160569
ENSG00000171530 UCEC Del 5.880987 0.094606 0.500446 0.202226
ENSG00000171530 OV Del 71.284162 0.669598 0.674993 0.716753