Ensembl ID ENSG00000171453 Gene ID 9533 Accession 20194
Gene Symbol POLR1C Alias AC40;RPA5;TCS3;HLD11;RPA39;RPA40;RPAC1;RPC40 Full Name RNA polymerase I and III subunit C
Position 6 : 43509702 - 43562419 Length 52718 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

ENSG00000171453 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000171453 POLR1C 0.51 2.61e-17 BRCA
ENSG00000171453 POLR1C 1.29 4.98e-46 COAD
ENSG00000171453 POLR1C -0.6 1.13e-13 KICH
ENSG00000171453 POLR1C 1.27 6.54e-12 READ
ENSG00000171453 POLR1C 1.00 2.30e-30 LUSC
ENSG00000171453 POLR1C 0.50 4.25e-15 PRAD
ENSG00000171453 POLR1C 0.85 1.36e-12 STAD
ENSG00000171453 POLR1C 0.80 1.22e-18 UCEC
ENSG00000171453 POLR1C 0.83 8.17e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000171453 POLR1C cancer 26442198
ENSG00000171453 POLR1C cancer 27341347
ENSG00000171453 POLR1C breast cancer 29263808
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000171453 POLR1C SARC 0.00037 high
ENSG00000171453 POLR1C STAD 0.015 low
ENSG00000171453 POLR1C UVM 0.048 high
ENSG00000171453 POLR1C UCEC 0.0055 high
ENSG00000171453 POLR1C ACC 0.033 high
ENSG00000171453 POLR1C LGG 0.042 low
ENSG00000171453 POLR1C LUSC 0.017 low
ENSG00000171453 POLR1C KIRP 0.0067 high
ENSG00000171453 POLR1C KICH 0.00048 high
ENSG00000171453 POLR1C LUAD 0.0087 low
ENSG00000171453 POLR1C THYM 0.00011 low
ENSG00000171453 POLR1C OV 0.0094 low
ENSG00000171453 POLR1C DLBC 0.0058 low
ENSG00000171453 POLR1C KIRC 0.00019 high
ENSG00000171453 POLR1C PRAD 0.0031 high
ENSG00000171453 POLR1C TGCT 0.041 low
ENSG00000171453 POLR1C BLCA 0.046 low
ENSG00000171453 POLR1C LIHC 0.0068 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000171453 POLR1C READ Amp 1.221755 0.152172 0.607495 0.327273
ENSG00000171453 POLR1C COAD Amp 1.623948 0.086042 0.532155 0.219512
ENSG00000171453 POLR1C ESCA Amp 8.526279 0.613687 0.970081 0.347826
ENSG00000171453 POLR1C SKCM Amp 0.738218 0.120599 0.736076 0.482289
ENSG00000171453 POLR1C LIHC Amp 4.752780 0.202293 0.799680 0.410811
ENSG00000171453 POLR1C BLCA Amp 1.912612 0.206966 0.563548 0.269608
ENSG00000171453 POLR1C STAD Amp 13.822609 0.387243 0.794056 0.276644
ENSG00000171453 POLR1C UVM Amp 1.949987 0.242456 1.088286 0.487500