Ensembl ID ENSG00000170606 Gene ID 3308 Accession 5237
Gene Symbol HSPA4 Alias RY;APG-2;HSPH2;hsp70;hsp70RY;HEL-S-5a;HS24/P52 Full Name heat shock protein family A (Hsp70) member 4
Position 5 : 133052013 - 133106449 Length 54437 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Predicted to enable ATP binding activity. Involved in chaperone-mediated protein complex assembly and protein insertion into mitochondrial outer membrane. Located in cytosol and extracellular exosome. Implicated in Chagas disease. Biomarker of chronic obstructive pulmonary disease; rheumatoid arthritis; type 2 diabetes mellitus; and ulcerative colitis. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000170606 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000170606 HSPA4 -0.5 5.16e-19 KIRC
ENSG00000170606 HSPA4 0.60 5.77e-29 BRCA
ENSG00000170606 HSPA4 0.49 4.98e-13 LUSC
ENSG00000170606 HSPA4 0.59 2.07e-13 LIHC
ENSG00000170606 HSPA4 0.73 2.41e-24 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000170606 HSPA4 tumour 24009892
ENSG00000170606 HSPA4 gastric cancer 25379943
ENSG00000170606 HSPA4 colorectal cancers 25437815
ENSG00000170606 HSPA4 gastric cancer 25655005
ENSG00000170606 HSPA4 tumour 25798051
ENSG00000170606 HSPA4 Colorectal Cancers 27129500
ENSG00000170606 HSPA4 Tumor 30643287
ENSG00000170606 HSPA4 tumor 30930989
ENSG00000170606 HSPA4 cancer 31814876
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000170606 HSPA4 UVM 0.004 high
ENSG00000170606 HSPA4 THCA 0.0014 high
ENSG00000170606 HSPA4 LGG 0.0092 high
ENSG00000170606 HSPA4 HNSC 0.0026 high
ENSG00000170606 HSPA4 READ 0.023 low
ENSG00000170606 HSPA4 KICH 0.014 high
ENSG00000170606 HSPA4 LUAD 0.00044 high
ENSG00000170606 HSPA4 THYM 0.021 low
ENSG00000170606 HSPA4 BRCA 0.036 high
ENSG00000170606 HSPA4 UCS 0.044 high
ENSG00000170606 HSPA4 KIRC 0.016 low
ENSG00000170606 HSPA4 LAML 0.012 high
ENSG00000170606 HSPA4 SKCM 0.0012 high
ENSG00000170606 HSPA4 LIHC 0.00016 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000170606 HSPA4 LAML Del 6.884155 0.097495 0.799843 0.089005
ENSG00000170606 HSPA4 LUAD Del 4.126237 0.086234 0.353261 0.406977
ENSG00000170606 HSPA4 LGG Del 0.962235 0.041998 0.393433 0.089669
ENSG00000170606 HSPA4 ACC Amp 1.248228 0.334625 1.279159 0.666667
ENSG00000170606 HSPA4 COAD Del 1.015796 0.046091 0.390908 0.223947
ENSG00000170606 HSPA4 SKCM Del 2.148303 0.088795 0.486939 0.318801
ENSG00000170606 HSPA4 HNSC Del 1.036539 0.058488 0.383732 0.394636
ENSG00000170606 HSPA4 STAD Del 4.012266 0.099673 0.396355 0.342404
ENSG00000170606 HSPA4 KIRC Amp 46.635937 0.275065 0.538141 0.596591
ENSG00000170606 HSPA4 OV Del 0.998585 0.181751 0.556594 0.466321