Ensembl ID ENSG00000170027 Gene ID 7532 Accession 12852
Gene Symbol YWHAG Alias DEE56;EIEE56;PPP1R170;14-3-3GAMMA Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
Position 7 : 76326799 - 76358991 Length 32193 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

ENSG00000170027 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000170027 -0.4 5.75e-16 BRCA
ENSG00000170027 0.44 2.14e-15 COAD
ENSG00000170027 0.91 1.65e-28 LUSC
ENSG00000170027 -2.3 1.20e-28 GBM
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000170027 breast cancer 27102539
ENSG00000170027 non-small cell lung cancer 27894843
ENSG00000170027 tumor 28126486
ENSG00000170027 Tumour 28432311
ENSG00000170027 lung cancer 29321819
ENSG00000170027 pancreatic cancer 31959150
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000170027 MESO 0.0052 high
ENSG00000170027 STAD 0.029 high
ENSG00000170027 CHOL 0.033 low
ENSG00000170027 UVM 0.00033 high
ENSG00000170027 PAAD 0.0011 high
ENSG00000170027 UCEC 0.018 low
ENSG00000170027 THCA 0.00055 high
ENSG00000170027 ACC 0.045 low
ENSG00000170027 LGG 0.00047 high
ENSG00000170027 HNSC 0.00039 high
ENSG00000170027 KIRP 0.0032 high
ENSG00000170027 PCPG 0.0093 low
ENSG00000170027 THYM 0.048 high
ENSG00000170027 BRCA 0.03 high
ENSG00000170027 COAD 0.016 high
ENSG00000170027 DLBC 0.048 low
ENSG00000170027 KIRC 0.0043 low
ENSG00000170027 LAML 0.0012 low
ENSG00000170027 GBM 0.0058 high
ENSG00000170027 SKCM 0.044 high
ENSG00000170027 CESC 0.00027 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency