Ensembl ID ENSG00000169946 Gene ID 23414 Accession 16700
Gene Symbol ZFPM2 Alias DIH3;FOG2;SRXY9;ZNF89B;hFOG-2;ZC2HC11B Full Name zinc finger protein, FOG family member 2
Position 8 : 105318438 - 105804539 Length 486102 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008]

ENSG00000169946 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000169946 -2.8 2.48e-15 BLCA
ENSG00000169946 -1.2 6.95e-28 BRCA
ENSG00000169946 -1.3 1.16e-17 LUSC
ENSG00000169946 -1.3 1.43e-13 LIHC
ENSG00000169946 -4.1 3.37e-51 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000169946 ovarian tumors 10999851
ENSG00000169946 tumors 14676824
ENSG00000169946 breast cancer 17310981
ENSG00000169946 tumours 19707195
ENSG00000169946 germ cell tumors 19969558
ENSG00000169946 cancer 20005803
ENSG00000169946 Wilms tumor 21411694
ENSG00000169946 tumor 21947875
ENSG00000169946 tumor 22545159
ENSG00000169946 tumors 23029311
ENSG00000169946 tumor 24762440
ENSG00000169946 cancers 24806839
ENSG00000169946 cancer 26207917
ENSG00000169946 tumor 26285119
ENSG00000169946 lung cancer 26314828
ENSG00000169946 cancer 28288173
ENSG00000169946 tumor 29985481
ENSG00000169946 lung cancer 30093726
ENSG00000169946 tumor 30347759
ENSG00000169946 breast cancer 30822522
ENSG00000169946 renal cell cancer 31298319
ENSG00000169946 Tumor 31406464
ENSG00000169946 tumor 31919993
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000169946 MESO 0.026 low
ENSG00000169946 SARC 0.05 low
ENSG00000169946 STAD 0.0045 high
ENSG00000169946 UVM 0.0014 high
ENSG00000169946 PAAD 0.029 high
ENSG00000169946 UCEC 0.009 high
ENSG00000169946 THCA 0.00022 high
ENSG00000169946 ACC 0.049 low
ENSG00000169946 LGG 0.018 low
ENSG00000169946 LUSC 0.00098 high
ENSG00000169946 KICH 0.014 high
ENSG00000169946 PCPG 0.0045 high
ENSG00000169946 BRCA 0.034 high
ENSG00000169946 COAD 0.033 high
ENSG00000169946 ESCA 0.013 low
ENSG00000169946 KIRC 0.015 high
ENSG00000169946 BLCA 0.022 high
ENSG00000169946 LAML 0.0028 high
ENSG00000169946 CESC 0.042 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000169946 LUSC Amp 3.387724 0.271090 0.551755 0.626747
ENSG00000169946 LUAD Amp 5.318927 0.208479 0.611765 0.571705
ENSG00000169946 LGG Amp 9.889635 0.149898 0.702943 0.175439
ENSG00000169946 CESC Amp 1.469360 0.158726 0.631150 0.379661
ENSG00000169946 READ Amp 2.311016 0.203796 0.800100 0.630303
ENSG00000169946 COAD Amp 4.385272 0.131027 0.785143 0.556541
ENSG00000169946 UCS Amp 0.762924 0.504138 1.124868 0.696429
ENSG00000169946 ESCA Amp 1.492262 0.310040 0.621192 0.684783
ENSG00000169946 SKCM Amp 1.713021 0.153345 0.764554 0.501362
ENSG00000169946 HNSC Amp 3.743941 0.181979 0.582625 0.701149
ENSG00000169946 LIHC Amp 16.166551 0.372344 1.190320 0.608108
ENSG00000169946 BLCA Amp 12.685556 0.438465 0.749107 0.610294
ENSG00000169946 BRCA Amp 42.790966 0.504737 1.051815 0.614815
ENSG00000169946 STAD Amp 4.141108 0.219757 0.611564 0.639456
ENSG00000169946 PRAD Amp 2.979298 0.076728 0.710324 0.319106
ENSG00000169946 UCEC Amp 2.005041 0.133096 0.801415 0.339518
ENSG00000169946 UVM Amp 9.477347 0.581109 1.507945 0.750000
ENSG00000169946 KICH Amp 0.662421 0.207384 0.962730 0.287879
ENSG00000169946 OV Amp 34.251764 0.870360 1.053014 0.644214