Ensembl ID ENSG00000169554 Gene ID 9839 Accession 14881
Gene Symbol ZEB2 Alias SIP1;SIP-1;ZFHX1B;HSPC082;SMADIP1 Full Name zinc finger E-box binding homeobox 2
Position 2 : 144364364 - 144521057 Length 156694 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]

ENSG00000169554 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000169554 0.67 3.78e-17 KIRC
ENSG00000169554 -2.0 2.10e-11 BLCA
ENSG00000169554 -1.5 1.38e-64 BRCA
ENSG00000169554 -1.4 6.90e-11 KICH
ENSG00000169554 -2.1 7.47e-54 LUSC
ENSG00000169554 -1.1 1.77e-14 PRAD
ENSG00000169554 -1.1 2.23e-13 LIHC
ENSG00000169554 -2.4 3.81e-37 UCEC
ENSG00000169554 -1.3 7.68e-25 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000169554 tumour 16495925
ENSG00000169554 tumor 16510593
ENSG00000169554 pancreatic cancer 17043655
ENSG00000169554 tumour 18376396
ENSG00000169554 cancer 18381893
ENSG00000169554 cancer 18411277
ENSG00000169554 tumors 19424592
ENSG00000169554 ovarian cancers 19486012
ENSG00000169554 AML 19549311
ENSG00000169554 colorectal cancer 19830559
ENSG00000169554 tumor 19839049
ENSG00000169554 ovarian cancer 19854497
ENSG00000169554 cancer 20025777
ENSG00000169554 tumors 20420713
ENSG00000169554 tumor 20473948
ENSG00000169554 tumor 20515682
ENSG00000169554 cancer 20592490
ENSG00000169554 cancer 20682048
ENSG00000169554 breast cancer 20813035
ENSG00000169554 lung cancer 20980099
ENSG00000169554 cancer 21044011
ENSG00000169554 tumor 21199805
ENSG00000169554 pancreatic cancer 21285251
ENSG00000169554 cancer 21303533
ENSG00000169554 tumor 21426561
ENSG00000169554 ovarian cancer 21529905
ENSG00000169554 tumor 21533028
ENSG00000169554 tumors 21637307
ENSG00000169554 breast cancer 21643534
ENSG00000169554 tumors 21673986
ENSG00000169554 tumor 21693763
ENSG00000169554 prostate cancer 21747944
ENSG00000169554 cancer 21874049
ENSG00000169554 breast cancers 21888691
ENSG00000169554 cancer 21890822
ENSG00000169554 tumor 21929751
ENSG00000169554 cancers 22000016
ENSG00000169554 colorectal cancer 22042972
ENSG00000169554 cancer 22227038
ENSG00000169554 tumors 22261801
ENSG00000169554 gastric cancer 22311119
ENSG00000169554 gastric cancer 22350782
ENSG00000169554 tumor 22393452
ENSG00000169554 tumor 22436613
ENSG00000169554 cancer 22586443
ENSG00000169554 tumors 22654675
ENSG00000169554 cancer 22753312
ENSG00000169554 tumor 22761708
ENSG00000169554 tumor 22892238
ENSG00000169554 prostate cancer 23024790
ENSG00000169554 cancer 23049906
ENSG00000169554 tumor 23112837
ENSG00000169554 gastric cancer 23143680
ENSG00000169554 renal cancer 23184150
ENSG00000169554 oral cancer 23188671
ENSG00000169554 GBMs 23268331
ENSG00000169554 endometrial cancer 23295740
ENSG00000169554 DLBCL 23342264
ENSG00000169554 colon cancer 23372686
ENSG00000169554 cancer 23376074
ENSG00000169554 tumor 23381389
ENSG00000169554 cancer 23408168
ENSG00000169554 breast cancer 23474752
ENSG00000169554 colon cancer 23596669
ENSG00000169554 cancer 23658743
ENSG00000169554 cancer 23708087
ENSG00000169554 tumor 23715501
ENSG00000169554 cancer 23888967
ENSG00000169554 cancer 24037528
ENSG00000169554 tumors 24040120
ENSG00000169554 HNSCC 24045665
ENSG00000169554 tumors 24091674
ENSG00000169554 breast cancer 24098490
ENSG00000169554 tumour 24127332
ENSG00000169554 tumor 24130169
ENSG00000169554 cancer 24165969
ENSG00000169554 cancer 24297751
ENSG00000169554 tumors of the urinary bladder 24306957
ENSG00000169554 cancer 24346158
ENSG00000169554 HNSCC 24424572
ENSG00000169554 tumor 24523727
ENSG00000169554 cancer 24598126
ENSG00000169554 Lung Cancer 24626466
ENSG00000169554 breast cancer 24710933
ENSG00000169554 small cell lung cancer 24769353
ENSG00000169554 cancer 24796549
ENSG00000169554 cancer 24810210
ENSG00000169554 prostate cancer 24812058
ENSG00000169554 breast tumors 24812525
ENSG00000169554 cancer 24814677
ENSG00000169554 colorectal cancer 24829139
ENSG00000169554 tumor 24880079
ENSG00000169554 gastric cancer 24885194
ENSG00000169554 colorectal cancer 24914372
ENSG00000169554 cancer 24918286
ENSG00000169554 tumor 24967704
ENSG00000169554 thyroid cancer 24968735
ENSG00000169554 tumor 25008569
ENSG00000169554 ovarian cancer 25052237
ENSG00000169554 breast cancer 25053741
ENSG00000169554 tumor 25157365
ENSG00000169554 head and neck cancers 25161999
ENSG00000169554 cancers 25197668
ENSG00000169554 gastric cancer 25270520
ENSG00000169554 prostate cancer 25296715
ENSG00000169554 tumors 25315069
ENSG00000169554 breast cancer 25329395
ENSG00000169554 breast cancer 25367080
ENSG00000169554 tumor 25427583
ENSG00000169554 gastric cancer 25435948
ENSG00000169554 cancer 25447746
ENSG00000169554 gastric cancer 25502084
ENSG00000169554 breast cancer 25520137
ENSG00000169554 cancers 25528769
ENSG00000169554 cancer 25556616
ENSG00000169554 tumour 25565005
ENSG00000169554 cancer 25678802
ENSG00000169554 tumors 25738652
ENSG00000169554 triple-negative breast cancer 25762639
ENSG00000169554 breast cancer 25779673
ENSG00000169554 breast cancer 25798919
ENSG00000169554 tumor 25818166
ENSG00000169554 tumor 25820676
ENSG00000169554 GBM 25833697
ENSG00000169554 gastric cancer 25945841
ENSG00000169554 ovarian cancer 25954928
ENSG00000169554 gastric cancer 25975736
ENSG00000169554 tumour 25989272
ENSG00000169554 Breast Cancer 26028330
ENSG00000169554 ovarian cancer 26136338
ENSG00000169554 tumor 26146543
ENSG00000169554 bladder cancer 26152796
ENSG00000169554 liver cancer 26156804
ENSG00000169554 tumor 26214683
ENSG00000169554 tumor 26220160
ENSG00000169554 tumor 26272668
ENSG00000169554 tumour 26293457
ENSG00000169554 breast cancer 26303947
ENSG00000169554 tumor 26378039
ENSG00000169554 tumor 26424075
ENSG00000169554 Tumor 26468984
ENSG00000169554 tumor 26472725
ENSG00000169554 cancer 26499780
ENSG00000169554 tumor 26503445
ENSG00000169554 tumor 26503460
ENSG00000169554 tumors 26517683
ENSG00000169554 bladder cancer 26544536
ENSG00000169554 cancer 26556542
ENSG00000169554 ovarian cancer 26607327
ENSG00000169554 non-small cell lung cancer 26622784
ENSG00000169554 Tumour 26633365
ENSG00000169554 Bladder Cancer 26646296
ENSG00000169554 cancer 26654950
ENSG00000169554 pancreatic cancer 26662405
ENSG00000169554 epithelial ovarian cancer 26714913
ENSG00000169554 prostate cancer 26784241
ENSG00000169554 breast cancer 26823172
ENSG00000169554 Ovarian Cancer 26824454
ENSG00000169554 cancers 26882562
ENSG00000169554 benign tumors 26893761
ENSG00000169554 tumor 26905733
ENSG00000169554 non-small cell lung cancer 26935975
ENSG00000169554 tumors 26996663
ENSG00000169554 breast cancer 27019625
ENSG00000169554 tumors 27023622
ENSG00000169554 tumor 27029067
ENSG00000169554 bladder cancer 27058893
ENSG00000169554 tumors 27059374
ENSG00000169554 gastric cancer 27143926
ENSG00000169554 cancer 27148353
ENSG00000169554 tumor 27276064
ENSG00000169554 breast cancer 27277676
ENSG00000169554 tumor 27284551
ENSG00000169554 renal cancer 27338343
ENSG00000169554 non-small cell lung cancer 27347142
ENSG00000169554 endometrial cancer 27349856
ENSG00000169554 AML 27447550
ENSG00000169554 tumour 27470974
ENSG00000169554 tumor 27549611
ENSG00000169554 bladder cancer 27577949
ENSG00000169554 tumor 27589832
ENSG00000169554 lung cancer 27733346
ENSG00000169554 tumor 27748842
ENSG00000169554 gastric cancer 27761656
ENSG00000169554 breast cancer 27785072
ENSG00000169554 breast cancer 27800618
ENSG00000169554 luminal breast cancer 27845906
ENSG00000169554 tumors 27861158
ENSG00000169554 tumor 27924058
ENSG00000169554 bladder cancer 27992370
ENSG00000169554 tumor 28042505
ENSG00000169554 breast cancer 28063065
ENSG00000169554 cancer 28064471
ENSG00000169554 cancer 28069602
ENSG00000169554 tumors 28100026
ENSG00000169554 tumor 28123534
ENSG00000169554 prostate cancer 28133913
ENSG00000169554 gastric cancer 28186964
ENSG00000169554 lung cancer 28192397
ENSG00000169554 tumour 28195647
ENSG00000169554 tumor 28209612
ENSG00000169554 breast cancer 28247944
ENSG00000169554 breast cancer 28279208
ENSG00000169554 prostate cancer 28302679
ENSG00000169554 lung cancer 28350117
ENSG00000169554 tumor 28356122
ENSG00000169554 cancers 28416756
ENSG00000169554 bladder cancer 28430163
ENSG00000169554 cancer 28437884
ENSG00000169554 gastric cancer 28485807
ENSG00000169554 bladder cancer 28503069
ENSG00000169554 tumor 28521482
ENSG00000169554 gastric cancer 28534959
ENSG00000169554 tumour 28544627
ENSG00000169554 tumor 28551696
ENSG00000169554 AML 28556516
ENSG00000169554 tumor 28569782
ENSG00000169554 cancers 28587302
ENSG00000169554 tumor 28608814
ENSG00000169554 tumor 28617555
ENSG00000169554 breast cancer 28618162
ENSG00000169554 Ovarian epithelial tumor 28623900
ENSG00000169554 esophageal cancer 28635228
ENSG00000169554 colorectal cancer 28670373
ENSG00000169554 breast cancer 28675122
ENSG00000169554 tumor 28680141
ENSG00000169554 cancer 28695799
ENSG00000169554 tumor 28739727
ENSG00000169554 cancer 28774834
ENSG00000169554 cancer 28783176
ENSG00000169554 esophageal cancer 28861321
ENSG00000169554 breast cancer 28880270
ENSG00000169554 breast cancer 28881990
ENSG00000169554 tumor 28890036
ENSG00000169554 tumor 28927031
ENSG00000169554 cancer 28982853
ENSG00000169554 bladder cancer 28992472
ENSG00000169554 prostate cancer 29022908
ENSG00000169554 gastric cancer 29052277
ENSG00000169554 tumor 29060924
ENSG00000169554 breast cancer 29104620
ENSG00000169554 small cell lung cancer 29115924
ENSG00000169554 Tumor 29150940
ENSG00000169554 renal cancer 29156724
ENSG00000169554 breast cancer 29164272
ENSG00000169554 colorectal cancer 29187907
ENSG00000169554 colon cancer 29202800
ENSG00000169554 breast cancer 29254230
ENSG00000169554 tumor 29258163
ENSG00000169554 gastric cancer 29302045
ENSG00000169554 non-small-cell lung cancer 29339211
ENSG00000169554 colon cancer 29339729
ENSG00000169554 papillary thyroid cancer 29344210
ENSG00000169554 tumor 29367761
ENSG00000169554 tumors 29375721
ENSG00000169554 cancer 29387204
ENSG00000169554 ovarian cancer 29389895
ENSG00000169554 cancer 29416649
ENSG00000169554 cancer 29463994
ENSG00000169554 tumor 29467869
ENSG00000169554 GBM 29476046
ENSG00000169554 cancer 29484121
ENSG00000169554 tumors 29516288
ENSG00000169554 Cervical Cancer 29523224
ENSG00000169554 tumor 29535552
ENSG00000169554 pancreatic cancer 29545841
ENSG00000169554 lung cancer 29552161
ENSG00000169554 tumors 29552328
ENSG00000169554 cancer 29559853
ENSG00000169554 tumor 29560266
ENSG00000169554 tumor 29666469
ENSG00000169554 bladder cancer 29678899
ENSG00000169554 gastric tumors 29719612
ENSG00000169554 tumor 29740212
ENSG00000169554 breast cancer 29744893
ENSG00000169554 pancreatic cancer 29753015
ENSG00000169554 colorectal cancer 29844832
ENSG00000169554 gastric cancers 29847827
ENSG00000169554 tumors 29854878
ENSG00000169554 tumors 29930325
ENSG00000169554 breast cancer 29963231
ENSG00000169554 tumor 29988972
ENSG00000169554 tumor 30008863
ENSG00000169554 lung cancer 30013636
ENSG00000169554 mammary cancer 30047225
ENSG00000169554 tumor 30087437
ENSG00000169554 cancer 30095616
ENSG00000169554 tumor 30157906
ENSG00000169554 cancer 30159422
ENSG00000169554 cancer 30175284
ENSG00000169554 cancers 30210690
ENSG00000169554 tumor 30214232
ENSG00000169554 pancreatic cancer 30250401
ENSG00000169554 cancer 30309355
ENSG00000169554 lung cancer 30349307
ENSG00000169554 bladder cancer 30352837
ENSG00000169554 breast cancer 30361097
ENSG00000169554 thyroid cancer 30415780
ENSG00000169554 breast cancer 30445998
ENSG00000169554 gastric cancer 30464170
ENSG00000169554 renal cancer 30488762
ENSG00000169554 cancer 30518916
ENSG00000169554 non-small cell lung cancer 30525209
ENSG00000169554 colon cancer 30530918
ENSG00000169554 non-small cell lung cancer 30542503
ENSG00000169554 tumors 30544196
ENSG00000169554 lung cancer 30568458
ENSG00000169554 tumor 30569446
ENSG00000169554 liver cancer 30592286
ENSG00000169554 Tumor 30596053
ENSG00000169554 triple-negative breast cancer 30611621
ENSG00000169554 gastric cancer 30635820
ENSG00000169554 tumors 30642115
ENSG00000169554 breast cancer 30645591
ENSG00000169554 Colorectal Cancer 30646215
ENSG00000169554 Colorectal Cancer 30646224
ENSG00000169554 breast cancer 30670688
ENSG00000169554 cancer 30679322
ENSG00000169554 cancers 30692230
ENSG00000169554 gastric cancer 30705594
ENSG00000169554 tumor 30719111
ENSG00000169554 tumor 30728039
ENSG00000169554 tumors 30739164
ENSG00000169554 cancer 30773635
ENSG00000169554 tumor 30780105
ENSG00000169554 cancer 30783098
ENSG00000169554 tumors 30790340
ENSG00000169554 Epithelial Ovarian Cancer 30814239
ENSG00000169554 triple-negative breast cancer 30825262
ENSG00000169554 trophoblastic tumors 30847562
ENSG00000169554 GBM 30867843
ENSG00000169554 tumor 30923258
ENSG00000169554 cancers 30950191
ENSG00000169554 laryngeal cancer 30957184
ENSG00000169554 breast cancer 30979827
ENSG00000169554 GBM 30990881
ENSG00000169554 cancers 31003545
ENSG00000169554 lung cancer 31024010
ENSG00000169554 tumors 31026342
ENSG00000169554 lung cancer 31037155
ENSG00000169554 head and neck cancer 31040921
ENSG00000169554 tumor 31056726
ENSG00000169554 tumour 31080552
ENSG00000169554 cancers 31122127
ENSG00000169554 gastric cancer 31128021
ENSG00000169554 tumours 31134511
ENSG00000169554 cancer 31186703
ENSG00000169554 lung cancer 31187349
ENSG00000169554 cancer 31200749
ENSG00000169554 lung cancer 31212916
ENSG00000169554 breast cancer 31214490
ENSG00000169554 cancer 31226520
ENSG00000169554 Non-Small Cell Lung Cancers 31244281
ENSG00000169554 bladder cancer 31253481
ENSG00000169554 tumor 31257481
ENSG00000169554 tumor 31295960
ENSG00000169554 Tumor 31336236
ENSG00000169554 colorectal cancer 31364113
ENSG00000169554 cancer 31383581
ENSG00000169554 esophageal cancer 31387451
ENSG00000169554 tumor 31429770
ENSG00000169554 non-small cell lung cancer 31452774
ENSG00000169554 colon cancer 31497237
ENSG00000169554 cervical cancer 31499118
ENSG00000169554 cancer 31564916
ENSG00000169554 tumour 31623346
ENSG00000169554 cancer 31659258
ENSG00000169554 tumor 31686846
ENSG00000169554 tumor 31695021
ENSG00000169554 colon cancer 31698657
ENSG00000169554 prostate cancer 31715665
ENSG00000169554 cancer 31723771
ENSG00000169554 bladder cancer 31746333
ENSG00000169554 Colorectal Cancer 31755734
ENSG00000169554 mammary cancer 31758045
ENSG00000169554 non-small cell lung cancer 31799665
ENSG00000169554 Non-Small Cell Lung Cancer 31807001
ENSG00000169554 tumor 31817495
ENSG00000169554 tumor 31819482
ENSG00000169554 tumor 31897212
ENSG00000169554 colorectal cancer 31910865
ENSG00000169554 tumor 31920337
ENSG00000169554 tumors 31921376
ENSG00000169554 colorectal cancer 31933004
ENSG00000169554 tumor 31934283
ENSG00000169554 colorectal cancer 31938180
ENSG00000169554 non-small cell lung cancer 31950837
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000169554 MESO 0.0014 high
ENSG00000169554 SARC 0.0015 low
ENSG00000169554 STAD 0.017 high
ENSG00000169554 CHOL 0.018 low
ENSG00000169554 THCA 0.027 high
ENSG00000169554 LUSC 0.0013 high
ENSG00000169554 HNSC 0.038 low
ENSG00000169554 READ 0.047 low
ENSG00000169554 ESCA 0.034 low
ENSG00000169554 TGCT 0.015 low
ENSG00000169554 BLCA 0.012 high
ENSG00000169554 LAML 0.029 low
ENSG00000169554 SKCM 0.0096 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000169554 LIHC Del 0.796261 0.067007 0.450646 0.132432
ENSG00000169554 DLBC Del 1.390620 0.164653 0.540253 0.166667
ENSG00000169554 BRCA Del 0.877280 0.065159 0.355780 0.245370
ENSG00000169554 STAD Del 0.833851 0.062602 0.344820 0.129252
ENSG00000169554 PRAD Del 14.385916 0.174720 0.505590 0.174797