Ensembl ID ENSG00000169249 Gene ID 8233 Accession 23019
Gene Symbol ZRSR2 Alias URP;ZC3H22;U2AF1L2;U2AF1RS2;U2AF1-RS2 Full Name zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
Position X : 15790156 - 15830694 Length 40539 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008]

ENSG00000169249 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000169249 ZRSR2 0.80 1.00e-36 KIRC
ENSG00000169249 ZRSR2 0.78 3.49e-11 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000169249 ZRSR2 cancers 23300180
ENSG00000169249 ZRSR2 AML 23645565
ENSG00000169249 ZRSR2 AML 25220401
ENSG00000169249 ZRSR2 AML 25550361
ENSG00000169249 ZRSR2 tumors 25586593
ENSG00000169249 ZRSR2 thyroid cancer 27010584
ENSG00000169249 ZRSR2 tumor 27256388
ENSG00000169249 ZRSR2 AML 27983727
ENSG00000169249 ZRSR2 AML 28321123
ENSG00000169249 ZRSR2 AML 28676493
ENSG00000169249 ZRSR2 AMLs 30813354
ENSG00000169249 ZRSR2 AML 31124956
ENSG00000169249 ZRSR2 AML 31334570
ENSG00000169249 ZRSR2 acute myeloid leukemia (AML) 31766606
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000169249 ZRSR2 myelodysplastic syndrome sequence_alteration 5.104% (81/1587) 6 entries
ENSG00000169249 ZRSR2 chronic myelomonocytic leukemia stop_gained 9.504% (23/242) 2 entries
ENSG00000169249 ZRSR2 myelodysplastic syndrome missense_variant 5.104% (81/1587) 4 entries
ENSG00000169249 ZRSR2 chronic myelomonocytic leukemia sequence_alteration 9.504% (23/242) 3 entries
ENSG00000169249 ZRSR2 chronic myelomonocytic leukemia amino_acid_insertion 9.504% (23/242) 1 entry
ENSG00000169249 ZRSR2 myelodysplastic syndrome amino_acid_insertion 5.104% (81/1587) 4 entries
ENSG00000169249 ZRSR2 colorectal adenocarcinoma stop_gained 2.571% (30/1167) 1 entry
ENSG00000169249 ZRSR2 colorectal adenocarcinoma missense_variant 2.571% (30/1167) 1 entry
ENSG00000169249 ZRSR2 myelodysplastic syndrome frameshift_variant 5.104% (81/1587) 7 entries
ENSG00000169249 ZRSR2 myelodysplastic syndrome stop_gained 5.104% (81/1587) 8 entries
ENSG00000169249 ZRSR2 chronic myelomonocytic leukemia missense_variant 9.504% (23/242) 2 entries
ENSG00000169249 ZRSR2 chronic myelomonocytic leukemia frameshift_variant 9.504% (23/242) 3 entries
ENSG00000169249 ZRSR2 colorectal adenocarcinoma sequence_alteration 2.571% (30/1167) 1 entry
ENSG00000169249 ZRSR2 prostate carcinoma sequence_alteration 0.939% (4/426) 1 entry
ENSG00000169249 ZRSR2 central nervous system primitive neuroectodermal neoplasm sequence_alteration 0.4464% (2/448) 1 entry
ENSG00000169249 ZRSR2 hemangioblastoma sequence_alteration 5.714% (2/35) 1 entry
ENSG00000169249 ZRSR2 small cell lung carcinoma missense_variant 0.4535% (2/441) 1 entry
ENSG00000169249 ZRSR2 breast ductal adenocarcinoma missense_variant 1.19% (19/1596) 1 entry
ENSG00000169249 ZRSR2 hepatocellular carcinoma stop_gained 0.5076% (5/985) 1 entry
ENSG00000169249 ZRSR2 chronic lymphocytic leukemia sequence_alteration 0.5605% (5/892) 1 entry
ENSG00000169249 ZRSR2 pancreatic ductal adenocarcinoma missense_variant 0.5855% (10/1708) 1 entry
ENSG00000169249 ZRSR2 bladder transitional cell carcinoma missense_variant 1.099% (5/455) 3 entries
ENSG00000169249 ZRSR2 acute myeloid leukemia sequence_alteration 0.9635% (33/3425) 1 entry
ENSG00000169249 ZRSR2 colorectal adenocarcinoma frameshift_variant 2.571% (30/1167) 1 entry
ENSG00000169249 ZRSR2 female breast carcinoma missense_variant 2.247% (6/267) 2 entries
ENSG00000169249 ZRSR2 breast ductal adenocarcinoma sequence_alteration 1.19% (19/1596) 1 entry
ENSG00000169249 ZRSR2 lung adenocarcinoma missense_variant 0.1968% (5/2541) 2 entries
ENSG00000169249 ZRSR2 melanoma missense_variant 4.138% (6/145) 2 entries
ENSG00000169249 ZRSR2 acute myeloid leukemia stop_gained 0.9635% (33/3425) 3 entries
ENSG00000169249 ZRSR2 acute myeloid leukemia frameshift_variant 0.9635% (33/3425) 4 entries
ENSG00000169249 ZRSR2 prostate carcinoma missense_variant 0.939% (4/426) 1 entry
ENSG00000169249 ZRSR2 breast carcinoma missense_variant 0.2708% (4/1477) 2 entries
ENSG00000169249 ZRSR2 acute myeloid leukemia missense_variant 0.9635% (33/3425) 5 entries
ENSG00000169249 ZRSR2 brain glioblastoma missense_variant 0.3298% (4/1213) 1 entry
ENSG00000169249 ZRSR2 Endometrial Endometrioid Adenocarcinoma missense_variant 1.546% (10/647) 1 entry
ENSG00000169249 ZRSR2 gastric intestinal type adenocarcinoma missense_variant 2.353% (2/85) 2 entries
ENSG00000169249 ZRSR2 T-cell acute lymphoblastic leukemia missense_variant 0.6494% (3/462) 1 entry
ENSG00000169249 ZRSR2 squamous cell lung carcinoma missense_variant 0.3219% (3/932) 1 entry
ENSG00000169249 ZRSR2 cecum adenocarcinoma missense_variant 0.7605% (2/263) 2 entries
ENSG00000169249 ZRSR2 colon adenocarcinoma sequence_alteration 1.038% (13/1253) 3 entries
ENSG00000169249 ZRSR2 colon adenocarcinoma missense_variant 1.038% (13/1253) 4 entries
ENSG00000169249 ZRSR2 PEComa missense_variant 6.667% (1/15) 1 entry
ENSG00000169249 ZRSR2 diffuse large B-cell lymphoma missense_variant 0.4762% (2/420) 1 entry
ENSG00000169249 ZRSR2 nasopharyngeal squamous cell carcinoma missense_variant 0.5556% (1/180) 1 entry
ENSG00000169249 ZRSR2 Breast Carcinoma by Gene Expression Profile amino_acid_insertion 4.082% (2/49) 1 entry
ENSG00000169249 ZRSR2 lung adenocarcinoma stop_gained 0.1968% (5/2541) 1 entry
ENSG00000169249 ZRSR2 rectal adenocarcinoma missense_variant 0.1832% (1/546) 1 entry
ENSG00000169249 ZRSR2 osteosarcoma missense_variant 0.6579% (1/152) 1 entry
ENSG00000169249 ZRSR2 breast ductal adenocarcinoma stop_gained 1.19% (19/1596) 1 entry
ENSG00000169249 ZRSR2 papillary renal cell carcinoma sequence_alteration 0.274% (1/365) 1 entry
ENSG00000169249 ZRSR2 lobular breast carcinoma sequence_alteration 0.8547% (2/234) 1 entry
ENSG00000169249 ZRSR2 lobular breast carcinoma missense_variant 0.8547% (2/234) 1 entry
ENSG00000169249 ZRSR2 melanoma frameshift_variant 4.138% (6/145) 1 entry
ENSG00000169249 ZRSR2 Hodgkins lymphoma amino_acid_insertion 2.469% (2/81) 1 entry
ENSG00000169249 ZRSR2 vulvar intraepithelial neoplasia missense_variant 9.091% (1/11) 1 entry
ENSG00000169249 ZRSR2 alveolar rhabdomyosarcoma missense_variant 1.562% (1/64) 1 entry
ENSG00000169249 ZRSR2 adrenal cortex carcinoma missense_variant 0.5291% (1/189) 1 entry
ENSG00000169249 ZRSR2 lung adenocarcinoma sequence_alteration 0.1968% (5/2541) 1 entry
ENSG00000169249 ZRSR2 ovarian serous adenocarcinoma missense_variant 0.1193% (1/838) 1 entry
ENSG00000169249 ZRSR2 Hodgkins lymphoma missense_variant 2.469% (2/81) 1 entry
ENSG00000169249 ZRSR2 anaplastic oligodendroglioma missense_variant 1.124% (1/89) 1 entry
ENSG00000169249 ZRSR2 Duodenal Adenocarcinoma missense_variant 5.882% (1/17) 1 entry
ENSG00000169249 ZRSR2 brain glioblastoma stop_gained 0.3298% (4/1213) 1 entry
ENSG00000169249 ZRSR2 Uveal Melanoma sequence_alteration 0.7812% (1/128) 1 entry
ENSG00000169249 ZRSR2 anaplastic astrocytoma missense_variant 0.7576% (1/132) 1 entry
ENSG00000169249 ZRSR2 Pleural Mesothelioma amino_acid_insertion 0.7042% (1/142) 1 entry
ENSG00000169249 ZRSR2 oral squamous cell carcinoma missense_variant 0.3817% (1/262) 1 entry
ENSG00000169249 ZRSR2 Endometrial Endometrioid Adenocarcinoma amino_acid_insertion 1.546% (10/647) 1 entry
ENSG00000169249 ZRSR2 Breast Carcinoma by Gene Expression Profile missense_variant 4.082% (2/49) 1 entry
ENSG00000169249 ZRSR2 Gallbladder Adenocarcinoma sequence_alteration 0.7194% (1/139) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000169249 ZRSR2 SARC 0.011 low
ENSG00000169249 ZRSR2 STAD 0.0073 low
ENSG00000169249 ZRSR2 CHOL 0.015 low
ENSG00000169249 ZRSR2 PAAD 0.018 low
ENSG00000169249 ZRSR2 UCEC 0.00011 high
ENSG00000169249 ZRSR2 THCA 0.013 low
ENSG00000169249 ZRSR2 ACC 0.014 high
ENSG00000169249 ZRSR2 LGG 0.001 high
ENSG00000169249 ZRSR2 KICH 0.011 high
ENSG00000169249 ZRSR2 LUAD 0.0093 low
ENSG00000169249 ZRSR2 BRCA 0.00021 low
ENSG00000169249 ZRSR2 ESCA 0.014 high
ENSG00000169249 ZRSR2 OV 0.01 low
ENSG00000169249 ZRSR2 LAML 0.0083 high
ENSG00000169249 ZRSR2 CESC 0.0083 low
ENSG00000169249 ZRSR2 LIHC 0.0046 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency