Ensembl ID ENSG00000169217 Gene ID 10421 Accession 1656
Gene Symbol CD2BP2 Alias LIN1;Snu40;FWP010;U5-52K;PPP1R59 Full Name CD2 cytoplasmic tail binding protein 2
Position 16 : 30350773 - 30355308 Length 4536 bases Strand Minus strand
Status Confidence Main interacting RNAssnRNARBP type Non-canonical_RBPs
Summary This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008]

ENSG00000169217 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000169217 CD2BP2 0.63 2.58e-28 BRCA
ENSG00000169217 CD2BP2 0.59 6.08e-11 KICH
ENSG00000169217 CD2BP2 0.59 7.34e-13 KIRP
ENSG00000169217 CD2BP2 0.56 2.01e-11 LIHC
ENSG00000169217 CD2BP2 1.09 2.18e-13 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000169217 CD2BP2 MESO 0.011 low
ENSG00000169217 CD2BP2 SARC 0.0066 low
ENSG00000169217 CD2BP2 CHOL 0.0014 low
ENSG00000169217 CD2BP2 PAAD 0.015 low
ENSG00000169217 CD2BP2 UCEC 0.0041 high
ENSG00000169217 CD2BP2 LUSC 0.01 low
ENSG00000169217 CD2BP2 READ 0.008 low
ENSG00000169217 CD2BP2 PCPG 0.044 low
ENSG00000169217 CD2BP2 THYM 0.025 low
ENSG00000169217 CD2BP2 COAD 0.004 high
ENSG00000169217 CD2BP2 ESCA 0.015 low
ENSG00000169217 CD2BP2 DLBC 0.024 low
ENSG00000169217 CD2BP2 KIRC 0.013 high
ENSG00000169217 CD2BP2 TGCT 0.031 low
ENSG00000169217 CD2BP2 LAML 0.00044 high
ENSG00000169217 CD2BP2 CESC 0.0059 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000169217 CD2BP2 UCS Amp 0.620785 0.478697 0.671162 0.357143