Ensembl ID
ENSG00000169180
Gene ID
23214
Accession
19733
Gene Symbol
XPO6
Alias
EXP6;RANBP20
Full Name
exportin 6
Position
16 : 28097976 - 28211965
Length
113990 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
ENSG00000169180 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000169180
XPO6
0.64
3.80e-55
BRCA
ENSG00000169180
XPO6
0.87
4.66e-25
KICH
ENSG00000169180
XPO6
0.56
7.55e-13
LUSC
ENSG00000169180
XPO6
0.74
2.90e-16
PRAD
ENSG00000169180
XPO6
0.60
6.79e-11
UCEC
ENSG00000169180
XPO6
0.46
2.79e-17
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000169180
XPO6
tumor
22210864
ENSG00000169180
XPO6
prostate cancer
25352753
ENSG00000169180
XPO6
tumor
26408707
ENSG00000169180
XPO6
prostate cancer
26709895
ENSG00000169180
XPO6
cancers
31414556
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000169180
XPO6
MESO
0.005
high
show
ENSG00000169180
XPO6
SARC
0.019
high
show
ENSG00000169180
XPO6
UVM
0.00013
high
show
ENSG00000169180
XPO6
THCA
0.031
high
show
ENSG00000169180
XPO6
ACC
0.0052
high
show
ENSG00000169180
XPO6
LGG
0.0011
high
show
ENSG00000169180
XPO6
READ
0.0023
low
show
ENSG00000169180
XPO6
KICH
0.028
high
show
ENSG00000169180
XPO6
PCPG
0.009
low
show
ENSG00000169180
XPO6
THYM
0.027
low
show
ENSG00000169180
XPO6
ESCA
0.014
low
show
ENSG00000169180
XPO6
OV
0.019
low
show
ENSG00000169180
XPO6
DLBC
0.042
high
show
ENSG00000169180
XPO6
BLCA
3e-04
high
show
ENSG00000169180
XPO6
LAML
0.01
high
show
ENSG00000169180
XPO6
CESC
0.0085
low
show
ENSG00000169180
XPO6
LIHC
0.00029
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
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