Ensembl ID
ENSG00000168724
Gene ID
134218
Accession
27030
Gene Symbol
DNAJC21
Alias
GS3;JJJ1;BMFS3;DNAJA5
Full Name
DnaJ heat shock protein family (Hsp40) member C21
Position
5 : 34929559 - 34958964
Length
29406 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Canonical_RBPs
Summary
This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the precursor 45S ribosomal RNA and may be involved in early nuclear ribosomal RNA biogenesis and maturation of the 60S ribosomal subunit. Mutations in this gene result in Bone marrow failure syndrome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2017]
ENSG00000168724 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000168724
DNAJC21
-0.3
2.40e-11
KIRC
ENSG00000168724
DNAJC21
0.56
5.73e-11
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000168724
DNAJC21
Cancer
27346687
ENSG00000168724
DNAJC21
AML
28942353
ENSG00000168724
DNAJC21
cancer
30755392
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000168724
DNAJC21
MESO
0.006
high
show
ENSG00000168724
DNAJC21
SARC
0.03
high
show
ENSG00000168724
DNAJC21
STAD
0.02
low
show
ENSG00000168724
DNAJC21
HNSC
0.019
low
show
ENSG00000168724
DNAJC21
READ
0.014
low
show
ENSG00000168724
DNAJC21
KIRP
0.0078
high
show
ENSG00000168724
DNAJC21
KICH
0.00096
high
show
ENSG00000168724
DNAJC21
LUAD
0.00035
low
show
ENSG00000168724
DNAJC21
OV
0.017
low
show
ENSG00000168724
DNAJC21
DLBC
0.012
high
show
ENSG00000168724
DNAJC21
PRAD
0.035
high
show
ENSG00000168724
DNAJC21
BLCA
0.039
low
show
ENSG00000168724
DNAJC21
CESC
0.045
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000168724
DNAJC21
LUSC
Amp
6.501639
0.335654
0.854332
0.738523
ENSG00000168724
DNAJC21
LUAD
Amp
4.859239
0.201166
0.699045
0.593023
ENSG00000168724
DNAJC21
ACC
Amp
1.228562
0.319262
1.268899
0.688889
ENSG00000168724
DNAJC21
COAD
Amp
0.920718
0.072040
0.552968
0.192905
ENSG00000168724
DNAJC21
SKCM
Amp
0.923656
0.127300
0.646359
0.247956
ENSG00000168724
DNAJC21
BLCA
Amp
0.712582
0.164225
0.771668
0.475490
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