Ensembl ID ENSG00000168439 Gene ID 10963 Accession 11387
Gene Symbol STIP1 Alias HOP;P60;STI1;STI1L;HEL-S-94n;IEF-SSP-3521 Full Name stress induced phosphoprotein 1
Position 11 : 64185272 - 64204543 Length 19272 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]

ENSG00000168439 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000168439 STIP1 0.54 2.67e-11 HNSC
ENSG00000168439 STIP1 1.01 3.18e-56 BRCA
ENSG00000168439 STIP1 0.77 1.23e-22 COAD
ENSG00000168439 STIP1 0.59 9.00e-13 KICH
ENSG00000168439 STIP1 1.06 9.36e-47 LUSC
ENSG00000168439 STIP1 0.90 7.10e-27 LIHC
ENSG00000168439 STIP1 0.85 9.50e-19 UCEC
ENSG00000168439 STIP1 0.83 6.32e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000168439 STIP1 tumor 17886292
ENSG00000168439 STIP1 tumours 19216797
ENSG00000168439 STIP1 ovarian cancer 20461751
ENSG00000168439 STIP1 ovarian cancer 20501939
ENSG00000168439 STIP1 lung cancer 20727180
ENSG00000168439 STIP1 tumor 21136681
ENSG00000168439 STIP1 cancer 21235734
ENSG00000168439 STIP1 breast cancer 21533148
ENSG00000168439 STIP1 GBM 22062133
ENSG00000168439 STIP1 lung cancer 22126541
ENSG00000168439 STIP1 cancer 22619672
ENSG00000168439 STIP1 cancer 22761953
ENSG00000168439 STIP1 ovarian cancer 22884369
ENSG00000168439 STIP1 cancer 22913813
ENSG00000168439 STIP1 cancer 23070844
ENSG00000168439 STIP1 ovarian cancer 23468915
ENSG00000168439 STIP1 cancer 23613750
ENSG00000168439 STIP1 pancreatic cancers 23737949
ENSG00000168439 STIP1 ovarian cancer 23915849
ENSG00000168439 STIP1 tumors 24069564
ENSG00000168439 STIP1 tumor 24163084
ENSG00000168439 STIP1 cancers 24278769
ENSG00000168439 STIP1 tumor 24488757
ENSG00000168439 STIP1 ovarian cancer 24654750
ENSG00000168439 STIP1 tumor 24764481
ENSG00000168439 STIP1 cancers 24884945
ENSG00000168439 STIP1 tumor 25034945
ENSG00000168439 STIP1 brain tumors 25042352
ENSG00000168439 STIP1 cancer 25159299
ENSG00000168439 STIP1 tumors 25177369
ENSG00000168439 STIP1 cancer 25949267
ENSG00000168439 STIP1 tumors 26011160
ENSG00000168439 STIP1 tumor 26388873
ENSG00000168439 STIP1 cancer 26664015
ENSG00000168439 STIP1 cancer 26847234
ENSG00000168439 STIP1 tumors 27002306
ENSG00000168439 STIP1 lung cancer 27026610
ENSG00000168439 STIP1 cancer 27218803
ENSG00000168439 STIP1 ovarian cancer 27409672
ENSG00000168439 STIP1 ovarian cancer 27681499
ENSG00000168439 STIP1 tumors 28186972
ENSG00000168439 STIP1 cancer 28199984
ENSG00000168439 STIP1 cancer 28559789
ENSG00000168439 STIP1 tumors 28620086
ENSG00000168439 STIP1 cancers 28852266
ENSG00000168439 STIP1 tumor 28887036
ENSG00000168439 STIP1 tumor 29335007
ENSG00000168439 STIP1 cancer 29559743
ENSG00000168439 STIP1 cancer 29593255
ENSG00000168439 STIP1 cancer 29596884
ENSG00000168439 STIP1 endometrial cancer 29673672
ENSG00000168439 STIP1 colorectal cancer 29879402
ENSG00000168439 STIP1 tumor 29914167
ENSG00000168439 STIP1 cancer 30076803
ENSG00000168439 STIP1 breast cancer 30211190
ENSG00000168439 STIP1 Endometrial Cancer 30283786
ENSG00000168439 STIP1 cancer 30423918
ENSG00000168439 STIP1 tumor 30472719
ENSG00000168439 STIP1 cancer 30697297
ENSG00000168439 STIP1 cancer 30740472
ENSG00000168439 STIP1 gastric cancer 30792867
ENSG00000168439 STIP1 breast cancer 30875365
ENSG00000168439 STIP1 colorectal cancer 31010128
ENSG00000168439 STIP1 tumor 31072879
ENSG00000168439 STIP1 tumor 31103826
ENSG00000168439 STIP1 Bladder Cancer 31250373
ENSG00000168439 STIP1 tumors 31447061
ENSG00000168439 STIP1 pancreatic cancer 31547977
ENSG00000168439 STIP1 cancer 31819639
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000168439 STIP1 MESO 0.00075 high
ENSG00000168439 STIP1 UVM 0.00089 high
ENSG00000168439 STIP1 PAAD 0.03 high
ENSG00000168439 STIP1 UCEC 0.038 low
ENSG00000168439 STIP1 THCA 0.022 low
ENSG00000168439 STIP1 LUSC 0.039 high
ENSG00000168439 STIP1 KICH 0.0027 high
ENSG00000168439 STIP1 LUAD 0.0027 high
ENSG00000168439 STIP1 THYM 0.043 low
ENSG00000168439 STIP1 BRCA 0.002 high
ENSG00000168439 STIP1 COAD 0.016 high
ENSG00000168439 STIP1 UCS 0.044 low
ENSG00000168439 STIP1 OV 0.02 low
ENSG00000168439 STIP1 DLBC 0.0059 low
ENSG00000168439 STIP1 KIRC 0.029 high
ENSG00000168439 STIP1 PRAD 0.0034 low
ENSG00000168439 STIP1 BLCA 0.03 high
ENSG00000168439 STIP1 LAML 0.0047 high
ENSG00000168439 STIP1 CESC 0.046 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000168439 STIP1 UCS Amp 1.541947 0.628592 0.939971 0.321429
ENSG00000168439 STIP1 HNSC Amp 4.520743 0.195383 0.455880 0.268199
ENSG00000168439 STIP1 BRCA Del 4.005899 0.087314 0.447957 0.224074
ENSG00000168439 STIP1 UCEC Amp 1.030587 0.111678 0.514785 0.124304