Ensembl ID ENSG00000168385 Gene ID 4735 Accession 7729
Gene Symbol SEPTIN2 Alias DIFF6;NEDD5;SEPT2;NEDD-5;Pnutl3;hNedd5 Full Name septin 2
Position 2 : 241315100 - 241354027 Length 38928 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary Enables identical protein binding activity. Predicted to be involved in several processes, including cilium assembly; regulation of exocytosis; and smoothened signaling pathway. Predicted to act upstream of or within regulation of L-glutamate import across plasma membrane and regulation of protein localization. Located in several cellular components, including cytoskeleton; photoreceptor connecting cilium; and sperm annulus. Part of septin complex. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000168385 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000168385 -0.2 1.11e-11 KIRC
ENSG00000168385 -1.1 7.92e-25 KICH
ENSG00000168385 -0.3 3.86e-16 PRAD
ENSG00000168385 1.07 2.14e-12 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000168385 AML 10485469
ENSG00000168385 brain tumors 15140406
ENSG00000168385 tumour 16739133
ENSG00000168385 tumor 17233837
ENSG00000168385 liver cancer 19165576
ENSG00000168385 cancer 20195767
ENSG00000168385 AML 21156246
ENSG00000168385 tumors 22424240
ENSG00000168385 tumor 26711338
ENSG00000168385 biliary tract cancer 27155525
ENSG00000168385 cancer 27248291
ENSG00000168385 breast cancer 27557506
ENSG00000168385 cancer 27878118
ENSG00000168385 tumor 27882315
ENSG00000168385 tumor 29724999
ENSG00000168385 tumor 30004646
ENSG00000168385 brain tumors 30444001
ENSG00000168385 epithelial ovarian cancer 31105878
ENSG00000168385 colorectal cancer 31402940
ENSG00000168385 prostate cancer 31903637
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000168385 MESO 0.0057 high
ENSG00000168385 SARC 0.00043 high
ENSG00000168385 UVM 0.0016 high
ENSG00000168385 PAAD 0.0017 high
ENSG00000168385 UCEC 0.026 high
ENSG00000168385 LGG 0.0099 low
ENSG00000168385 LUSC 0.048 high
ENSG00000168385 LUAD 0.0019 high
ENSG00000168385 PCPG 0.00066 high
ENSG00000168385 COAD 0.04 low
ENSG00000168385 UCS 0.00044 high
ENSG00000168385 ESCA 0.015 high
ENSG00000168385 BLCA 0.014 high
ENSG00000168385 GBM 0.00041 low
ENSG00000168385 SKCM 0.0012 low
ENSG00000168385 LIHC 0.00051 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000168385 LUSC Del 18.135551 0.201835 0.395452 0.315369
ENSG00000168385 LUAD Del 0.967315 0.055182 0.300717 0.125969
ENSG00000168385 LGG Del 19.076828 0.148574 0.549161 0.146199
ENSG00000168385 CESC Del 38.528251 0.375441 0.552159 0.410169
ENSG00000168385 KIRP Amp 1.259300 0.069729 0.555924 0.156250
ENSG00000168385 KIRP Del 3.702987 0.054508 0.678615 0.041667
ENSG00000168385 ACC Del 1.060447 0.113077 0.545494 0.233333
ENSG00000168385 SARC Del 31.283075 0.527002 0.678623 0.420233
ENSG00000168385 ESCA Del 4.984103 0.198290 0.416446 0.282609
ENSG00000168385 SKCM Del 8.356212 0.154875 0.476546 0.247956
ENSG00000168385 HNSC Del 23.625698 0.190812 0.385129 0.296935
ENSG00000168385 LIHC Del 2.777430 0.095975 0.423513 0.170270
ENSG00000168385 TGCT Del 1.108882 0.067846 0.350636 0.120000
ENSG00000168385 BLCA Del 33.664078 0.334613 0.468380 0.492647
ENSG00000168385 BRCA Del 10.328805 0.115984 0.370621 0.295370
ENSG00000168385 STAD Del 5.599107 0.113420 0.375689 0.165533
ENSG00000168385 UCEC Del 3.044090 0.072913 0.478215 0.094620
ENSG00000168385 KIRC Del 14.666844 0.082429 0.549033 0.092803
ENSG00000168385 UVM Del 1.063142 0.075786 0.967811 0.037500
ENSG00000168385 OV Del 9.154354 0.291885 0.538375 0.305699