Ensembl ID ENSG00000167658 Gene ID 1938 Accession 3214
Gene Symbol EEF2 Alias EF2;EF-2;EEF-2;SCA26 Full Name eukaryotic translation elongation factor 2
Position 19 : 3976056 - 3985463 Length 9408 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]

ENSG00000167658 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000167658 EEF2 0.46 5.77e-14 KIRC
ENSG00000167658 EEF2 -0.6 3.06e-14 HNSC
ENSG00000167658 EEF2 1.31 1.59e-20 KICH
ENSG00000167658 EEF2 0.59 3.99e-17 PRAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000167658 EEF2 breast cancer 10408694
ENSG00000167658 EEF2 Malignant tumors 11254220
ENSG00000167658 EEF2 tumor 1517572
ENSG00000167658 EEF2 breast cancer 15289310
ENSG00000167658 EEF2 cancer 15322237
ENSG00000167658 EEF2 tumor 15637051
ENSG00000167658 EEF2 tumor 15660415
ENSG00000167658 EEF2 tumor 16168106
ENSG00000167658 EEF2 cancer 16534844
ENSG00000167658 EEF2 breast cancer 16648488
ENSG00000167658 EEF2 prostate cancer 18991566
ENSG00000167658 EEF2 cancers 19360331
ENSG00000167658 EEF2 cancer 19546037
ENSG00000167658 EEF2 breast cancer 20300520
ENSG00000167658 EEF2 cancer 21042741
ENSG00000167658 EEF2 breast cancer 22911754
ENSG00000167658 EEF2 cancer 23443080
ENSG00000167658 EEF2 cancers 23544955
ENSG00000167658 EEF2 tumor 24130777
ENSG00000167658 EEF2 pancreatic cancer 24193916
ENSG00000167658 EEF2 non-small cell lung cancer 24377563
ENSG00000167658 EEF2 cancer 24589652
ENSG00000167658 EEF2 breast cancer 24867631
ENSG00000167658 EEF2 cancer 24891364
ENSG00000167658 EEF2 colon cancer 24955726
ENSG00000167658 EEF2 tumour 2510715
ENSG00000167658 EEF2 pancreatic cancer 25215932
ENSG00000167658 EEF2 GBM 25346520
ENSG00000167658 EEF2 cancer 25352115
ENSG00000167658 EEF2 tumor 25700642
ENSG00000167658 EEF2 cancer 26304717
ENSG00000167658 EEF2 liver cancer 26633388
ENSG00000167658 EEF2 cancer 2693515
ENSG00000167658 EEF2 tumor 27542262
ENSG00000167658 EEF2 cancer 27964761
ENSG00000167658 EEF2 triple-negative breast cancer 28036267
ENSG00000167658 EEF2 tumor 28245596
ENSG00000167658 EEF2 Prostate Cancer 28913610
ENSG00000167658 EEF2 cancers 29282095
ENSG00000167658 EEF2 tumor 29342219
ENSG00000167658 EEF2 triple-negative breast cancer 29971628
ENSG00000167658 EEF2 tumor 30060827
ENSG00000167658 EEF2 non-small-cell lung cancer 30147338
ENSG00000167658 EEF2 lung cancer 30268477
ENSG00000167658 EEF2 cancer 30290014
ENSG00000167658 EEF2 cancer 30821613
ENSG00000167658 EEF2 colon cancer 31227218
ENSG00000167658 EEF2 lung cancer 31399076
ENSG00000167658 EEF2 breast cancer 31432749
ENSG00000167658 EEF2 breast cancer 31555351
ENSG00000167658 EEF2 gastric cancer 31558304
ENSG00000167658 EEF2 tumor 31590382
ENSG00000167658 EEF2 tumor 3273203
ENSG00000167658 EEF2 tumor 3390175
ENSG00000167658 EEF2 tumor 4475638
ENSG00000167658 EEF2 tumors 6307688
ENSG00000167658 EEF2 tumour 6673428
ENSG00000167658 EEF2 tumor 6850553
ENSG00000167658 EEF2 tumor 9823325
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000167658 EEF2 STAD 0.05 low
ENSG00000167658 EEF2 UVM 0.00095 low
ENSG00000167658 EEF2 PAAD 0.007 low
ENSG00000167658 EEF2 THCA 0.041 high
ENSG00000167658 EEF2 ACC 0.006 high
ENSG00000167658 EEF2 KIRP 0.031 high
ENSG00000167658 EEF2 PCPG 0.0093 high
ENSG00000167658 EEF2 BRCA 0.025 low
ENSG00000167658 EEF2 ESCA 0.0013 low
ENSG00000167658 EEF2 OV 0.011 high
ENSG00000167658 EEF2 GBM 0.027 low
ENSG00000167658 EEF2 SKCM 0.022 high
ENSG00000167658 EEF2 LIHC 0.05 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000167658 EEF2 LUSC Del 5.369587 0.116477 0.349834 0.437126
ENSG00000167658 EEF2 LUAD Del 3.925979 0.084556 0.350868 0.542636
ENSG00000167658 EEF2 CESC Del 10.945934 0.184234 0.471708 0.342373
ENSG00000167658 EEF2 KIRP Del 1.233091 0.032329 0.413260 0.079861
ENSG00000167658 EEF2 READ Del 0.637830 0.068240 0.350590 0.224242
ENSG00000167658 EEF2 COAD Del 0.809077 0.043450 0.374321 0.128603
ENSG00000167658 EEF2 UCS Del 11.305682 0.742389 0.633290 0.803571
ENSG00000167658 EEF2 PAAD Del 1.468663 0.061193 0.349553 0.184783
ENSG00000167658 EEF2 ESCA Del 1.459671 0.118268 0.335006 0.478261
ENSG00000167658 EEF2 THCA Del 0.928265 0.010197 0.634285 0.016032
ENSG00000167658 EEF2 HNSC Del 8.392918 0.112828 0.344304 0.295019
ENSG00000167658 EEF2 LIHC Del 6.763145 0.138696 0.473416 0.237838
ENSG00000167658 EEF2 BLCA Del 4.267602 0.126044 0.341088 0.352941
ENSG00000167658 EEF2 BRCA Del 11.052725 0.118791 0.377584 0.290741
ENSG00000167658 EEF2 STAD Del 4.236738 0.101637 0.367336 0.371882
ENSG00000167658 EEF2 UCEC Del 48.345352 0.280605 0.598908 0.289425
ENSG00000167658 EEF2 OV Del 121.432427 0.882388 0.650465 0.863558