Ensembl ID ENSG00000166986 Gene ID 4141 Accession 6898
Gene Symbol MARS1 Alias MRS;ILLD;MARS;TTD9;CMT2U;ILFS2;METRS;MTRNS;SPG70 Full Name methionyl-tRNA synthetase 1
Position 12 : 57487294 - 57517569 Length 30276 bases Strand Plus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [provided by RefSeq, Jan 2011]

ENSG00000166986 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000166986 MARS1 0.71 4.98e-53 BRCA
ENSG00000166986 MARS1 0.78 7.83e-23 COAD
ENSG00000166986 MARS1 0.86 2.17e-18 KICH
ENSG00000166986 MARS1 0.97 8.77e-50 LUSC
ENSG00000166986 MARS1 0.64 4.31e-18 LIHC
ENSG00000166986 MARS1 1.02 1.02e-35 UCEC
ENSG00000166986 MARS1 0.83 1.73e-23 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000166986 MARS1 tumor 18343821
ENSG00000166986 MARS1 tumor 22106287
ENSG00000166986 MARS1 cancer 26159576
ENSG00000166986 MARS1 non-small cell lung cancer 28679377
ENSG00000166986 MARS1 Non-Small Cell Lung Cancer 31637881
ENSG00000166986 MARS1 bile duct cancer 31874158
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000166986 MARS1 SARC 0.00058 high
ENSG00000166986 MARS1 STAD 0.0055 low
ENSG00000166986 MARS1 UVM 0.0021 high
ENSG00000166986 MARS1 PAAD 0.036 low
ENSG00000166986 MARS1 HNSC 0.0023 high
ENSG00000166986 MARS1 KICH 0.00018 high
ENSG00000166986 MARS1 PCPG 0.024 low
ENSG00000166986 MARS1 THYM 0.0027 low
ENSG00000166986 MARS1 BRCA 0.00053 high
ENSG00000166986 MARS1 COAD 0.0064 high
ENSG00000166986 MARS1 DLBC 0.0017 high
ENSG00000166986 MARS1 PRAD 0.017 low
ENSG00000166986 MARS1 BLCA 0.038 high
ENSG00000166986 MARS1 LAML 0.0017 high
ENSG00000166986 MARS1 GBM 0.023 low
ENSG00000166986 MARS1 SKCM 0.019 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000166986 MARS1 LUAD Amp 4.201186 0.190324 0.510303 0.308140
ENSG00000166986 MARS1 LGG Amp 17.049113 0.221263 1.748726 0.054581
ENSG00000166986 MARS1 ACC Amp 1.656823 0.404345 1.184924 0.766667
ENSG00000166986 MARS1 SARC Amp 3.972754 0.414930 1.199971 0.186770
ENSG00000166986 MARS1 GBM Amp 53.060775 0.575991 1.729374 0.162912
ENSG00000166986 MARS1 SKCM Amp 3.232269 0.196108 0.784525 0.141689