Ensembl ID ENSG00000166598 Gene ID 7184 Accession 12028
Gene Symbol HSP90B1 Alias ECGP;GP96;TRA1;GRP94;HEL35;HEL-S-125m Full Name heat shock protein 90 beta family member 1
Position 12 : 103930107 - 103953931 Length 23825 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]

ENSG00000166598 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000166598 HSP90B1 0.73 4.21e-21 HNSC
ENSG00000166598 HSP90B1 0.44 2.55e-16 BRCA
ENSG00000166598 HSP90B1 0.84 1.52e-28 LUSC
ENSG00000166598 HSP90B1 0.70 4.24e-11 UCEC
ENSG00000166598 HSP90B1 0.93 5.49e-27 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000166598 HSP90B1 tumor 10207025
ENSG00000166598 HSP90B1 tumors 10352256
ENSG00000166598 HSP90B1 tumors 10424404
ENSG00000166598 HSP90B1 tumor 10597632
ENSG00000166598 HSP90B1 tumor 10934286
ENSG00000166598 HSP90B1 tumour 11803053
ENSG00000166598 HSP90B1 Tumor 12461080
ENSG00000166598 HSP90B1 lung cancer 12609072
ENSG00000166598 HSP90B1 tumors 12669247
ENSG00000166598 HSP90B1 tumor 12805368
ENSG00000166598 HSP90B1 tumor 15034032
ENSG00000166598 HSP90B1 cancer 15270080
ENSG00000166598 HSP90B1 tumor 15633290
ENSG00000166598 HSP90B1 breast cancer 15750928
ENSG00000166598 HSP90B1 prostate cancer 16204082
ENSG00000166598 HSP90B1 tumor 16230366
ENSG00000166598 HSP90B1 tumours 16274472
ENSG00000166598 HSP90B1 lung cancer 16297569
ENSG00000166598 HSP90B1 cervical cancer 16368648
ENSG00000166598 HSP90B1 tumors 16772370
ENSG00000166598 HSP90B1 cancer 16861902
ENSG00000166598 HSP90B1 tumors 17545519
ENSG00000166598 HSP90B1 tumor 17971859
ENSG00000166598 HSP90B1 tumor 18273841
ENSG00000166598 HSP90B1 tumors 18331622
ENSG00000166598 HSP90B1 prostate cancer 18340425
ENSG00000166598 HSP90B1 colon cancer 19118525
ENSG00000166598 HSP90B1 tumor 19205439
ENSG00000166598 HSP90B1 lung cancer 19212831
ENSG00000166598 HSP90B1 pancreatic cancer 19724918
ENSG00000166598 HSP90B1 breast cancer 20208520
ENSG00000166598 HSP90B1 cancer 20520781
ENSG00000166598 HSP90B1 cancer 20942857
ENSG00000166598 HSP90B1 tumors 21345215
ENSG00000166598 HSP90B1 tumor 21472681
ENSG00000166598 HSP90B1 cancers 21489244
ENSG00000166598 HSP90B1 cancer 21647226
ENSG00000166598 HSP90B1 breast tumors 21968807
ENSG00000166598 HSP90B1 tumour 22152070
ENSG00000166598 HSP90B1 breast cancer 22245095
ENSG00000166598 HSP90B1 Breast Cancer 22363530
ENSG00000166598 HSP90B1 Tumor 22508478
ENSG00000166598 HSP90B1 cancer 22713763
ENSG00000166598 HSP90B1 cancer 22911792
ENSG00000166598 HSP90B1 prostate cancer 23251452
ENSG00000166598 HSP90B1 lung cancer 23374247
ENSG00000166598 HSP90B1 tumor 23553442
ENSG00000166598 HSP90B1 colon cancer 23737015
ENSG00000166598 HSP90B1 cancer 23755301
ENSG00000166598 HSP90B1 gastric cancer 23829397
ENSG00000166598 HSP90B1 tumours 23839491
ENSG00000166598 HSP90B1 cervical cancer 23929391
ENSG00000166598 HSP90B1 liver tumors 24027047
ENSG00000166598 HSP90B1 tumor 24039668
ENSG00000166598 HSP90B1 tumor 24058864
ENSG00000166598 HSP90B1 non-small cell lung cancer 24511009
ENSG00000166598 HSP90B1 colon cancer 24778928
ENSG00000166598 HSP90B1 breast cancer 24953136
ENSG00000166598 HSP90B1 cancers 25007077
ENSG00000166598 HSP90B1 tumor 25220589
ENSG00000166598 HSP90B1 gastric cancer 25295093
ENSG00000166598 HSP90B1 tumor 25386408
ENSG00000166598 HSP90B1 tumor 25546329
ENSG00000166598 HSP90B1 tumor 25610811
ENSG00000166598 HSP90B1 cancer 25629003
ENSG00000166598 HSP90B1 ovarian cancer 25688334
ENSG00000166598 HSP90B1 tumour 25798051
ENSG00000166598 HSP90B1 tumor 25880332
ENSG00000166598 HSP90B1 gastric cancer 26050197
ENSG00000166598 HSP90B1 tumor 26108672
ENSG00000166598 HSP90B1 tumor 26351857
ENSG00000166598 HSP90B1 tumors 26464709
ENSG00000166598 HSP90B1 cancer 26493996
ENSG00000166598 HSP90B1 tumors 26497551
ENSG00000166598 HSP90B1 cancer 26718209
ENSG00000166598 HSP90B1 Cancer 26872972
ENSG00000166598 HSP90B1 endometrial cancer 26910913
ENSG00000166598 HSP90B1 Cancer 26916005
ENSG00000166598 HSP90B1 cancer 27046189
ENSG00000166598 HSP90B1 colon cancer 27369741
ENSG00000166598 HSP90B1 malignant tumors 27468826
ENSG00000166598 HSP90B1 breast cancer 27525228
ENSG00000166598 HSP90B1 tumor 27649068
ENSG00000166598 HSP90B1 lung cancer 27829290
ENSG00000166598 HSP90B1 tumors 27835579
ENSG00000166598 HSP90B1 cancer 27846214
ENSG00000166598 HSP90B1 cancer 27846717
ENSG00000166598 HSP90B1 cancer 28248271
ENSG00000166598 HSP90B1 tumor 28358273
ENSG00000166598 HSP90B1 tumors 28670517
ENSG00000166598 HSP90B1 Tumor 28882998
ENSG00000166598 HSP90B1 breast cancer 29137250
ENSG00000166598 HSP90B1 tumors 29250484
ENSG00000166598 HSP90B1 papillary thyroid cancer 29368272
ENSG00000166598 HSP90B1 tumour 29374142
ENSG00000166598 HSP90B1 cancer 29507700
ENSG00000166598 HSP90B1 tumours 29702669
ENSG00000166598 HSP90B1 cancers 29729432
ENSG00000166598 HSP90B1 tumor 30157864
ENSG00000166598 HSP90B1 tumour 30158430
ENSG00000166598 HSP90B1 Cancer 30210606
ENSG00000166598 HSP90B1 tumor 30709011
ENSG00000166598 HSP90B1 cancer 30719181
ENSG00000166598 HSP90B1 tumor 30930968
ENSG00000166598 HSP90B1 tumor 31146747
ENSG00000166598 HSP90B1 tumor 31395819
ENSG00000166598 HSP90B1 bladder cancer 31615303
ENSG00000166598 HSP90B1 tumour 31616529
ENSG00000166598 HSP90B1 tumors 31637425
ENSG00000166598 HSP90B1 Colorectal Cancer 31683810
ENSG00000166598 HSP90B1 tumor 31933908
ENSG00000166598 HSP90B1 breast cancer 31938432
ENSG00000166598 HSP90B1 tumor 31970893
ENSG00000166598 HSP90B1 tumor 8058109
ENSG00000166598 HSP90B1 tumor 9407008
ENSG00000166598 HSP90B1 cancer 9523119
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000166598 HSP90B1 MESO 0.0031 high
ENSG00000166598 HSP90B1 CHOL 0.0023 high
ENSG00000166598 HSP90B1 UVM 0.016 high
ENSG00000166598 HSP90B1 UCEC 0.042 low
ENSG00000166598 HSP90B1 THCA 0.05 high
ENSG00000166598 HSP90B1 ACC 0.00011 high
ENSG00000166598 HSP90B1 HNSC 0.005 high
ENSG00000166598 HSP90B1 KICH 0.00055 high
ENSG00000166598 HSP90B1 PCPG 0.012 low
ENSG00000166598 HSP90B1 THYM 0.0019 low
ENSG00000166598 HSP90B1 BRCA 0.028 low
ENSG00000166598 HSP90B1 COAD 0.042 low
ENSG00000166598 HSP90B1 UCS 0.024 low
ENSG00000166598 HSP90B1 ESCA 0.00017 high
ENSG00000166598 HSP90B1 OV 0.026 low
ENSG00000166598 HSP90B1 TGCT 0.041 high
ENSG00000166598 HSP90B1 BLCA 0.036 high
ENSG00000166598 HSP90B1 LAML 0.00023 low
ENSG00000166598 HSP90B1 GBM 0.014 high
ENSG00000166598 HSP90B1 SKCM 0.002 low
ENSG00000166598 HSP90B1 CESC 0.05 high
ENSG00000166598 HSP90B1 LIHC 0.0058 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000166598 HSP90B1 CHOL Del 0.852431 0.219537 0.589045 0.222222
ENSG00000166598 HSP90B1 LUAD Del 0.779862 0.052244 0.285869 0.240310
ENSG00000166598 HSP90B1 PAAD Del 1.597047 0.063547 0.352967 0.228261
ENSG00000166598 HSP90B1 SKCM Del 1.892847 0.084960 0.437253 0.247956
ENSG00000166598 HSP90B1 BRCA Del 2.909927 0.080798 0.389648 0.187963
ENSG00000166598 HSP90B1 PRAD Amp 0.614926 0.043905 0.490158 0.069106
ENSG00000166598 HSP90B1 OV Del 2.718236 0.214847 0.566666 0.331606