Ensembl ID ENSG00000166477 Gene ID 123169 Accession 30401
Gene Symbol LEO1 Alias RDL Full Name LEO1 homolog, Paf1/RNA polymerase II complex component
Position 15 : 51938025 - 51971778 Length 33754 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM, Mar 2008]

ENSG00000166477 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000166477 LEO1 0.82 1.75e-37 BRCA
ENSG00000166477 LEO1 0.71 6.27e-25 LUSC
ENSG00000166477 LEO1 0.43 4.80e-13 PRAD
ENSG00000166477 LEO1 0.51 2.79e-16 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000166477 LEO1 AML 24237598
ENSG00000166477 LEO1 cancer 25115385
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000166477 LEO1 MESO 0.015 high
ENSG00000166477 LEO1 SARC 0.023 high
ENSG00000166477 LEO1 UCEC 0.0025 low
ENSG00000166477 LEO1 THCA 0.018 low
ENSG00000166477 LEO1 ACC 0.028 high
ENSG00000166477 LEO1 LGG 0.0062 low
ENSG00000166477 LEO1 LUSC 0.0064 low
ENSG00000166477 LEO1 KICH 0.00022 high
ENSG00000166477 LEO1 LUAD 0.0019 high
ENSG00000166477 LEO1 THYM 0.04 low
ENSG00000166477 LEO1 BRCA 0.012 high
ENSG00000166477 LEO1 PRAD 0.00023 low
ENSG00000166477 LEO1 BLCA 0.021 high
ENSG00000166477 LEO1 LAML 0.041 low
ENSG00000166477 LEO1 GBM 0.025 low
ENSG00000166477 LEO1 SKCM 0.0061 low
ENSG00000166477 LEO1 CESC 0.015 high
ENSG00000166477 LEO1 LIHC 0.0096 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000166477 LEO1 CESC Del 2.672398 0.101292 0.469035 0.223729
ENSG00000166477 LEO1 UCS Del 2.897474 0.363461 0.529277 0.696429
ENSG00000166477 LEO1 GBM Del 2.449277 0.071676 0.474319 0.230503
ENSG00000166477 LEO1 SKCM Del 2.824962 0.097645 0.454499 0.215259
ENSG00000166477 LEO1 BRCA Del 3.133582 0.082201 0.389918 0.329630
ENSG00000166477 LEO1 STAD Del 0.813384 0.062357 0.329595 0.247166
ENSG00000166477 LEO1 UCEC Del 2.813382 0.070905 0.505749 0.248609
ENSG00000166477 LEO1 OV Del 1.796255 0.198766 0.561231 0.540587