Ensembl ID ENSG00000166226 Gene ID 10576 Accession 1615
Gene Symbol CCT2 Alias CCTB;99D8.1;PRO1633;CCT-beta;HEL-S-100n;TCP-1-beta Full Name chaperonin containing TCP1 subunit 2
Position 12 : 69585459 - 69601570 Length 16112 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

ENSG00000166226 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000166226 0.74 3.55e-26 BRCA
ENSG00000166226 1.03 2.04e-36 COAD
ENSG00000166226 1.15 6.10e-28 LUSC
ENSG00000166226 0.43 3.61e-15 PRAD
ENSG00000166226 1.02 2.80e-13 STAD
ENSG00000166226 0.73 1.87e-19 UCEC
ENSG00000166226 0.84 3.45e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000166226 colorectal cancer 16981251
ENSG00000166226 tumour 19284299
ENSG00000166226 tumors 19690144
ENSG00000166226 tumor 21973086
ENSG00000166226 cancer 23190606
ENSG00000166226 tumor 23782473
ENSG00000166226 breast cancer 25704758
ENSG00000166226 breast cancer 29112949
ENSG00000166226 lung cancer 29299146
ENSG00000166226 prostate cancer 30897525
ENSG00000166226 tumor 30987822
ENSG00000166226 cancers 31101846
ENSG00000166226 colorectal cancer 31462707
ENSG00000166226 tumor 31934176
ENSG00000166226 breast cancer 31964905
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000166226 MESO 0.00037 high
ENSG00000166226 SARC 0.00017 high
ENSG00000166226 PAAD 0.01 high
ENSG00000166226 ACC 0.00041 high
ENSG00000166226 HNSC 0.00078 high
ENSG00000166226 READ 0.0074 low
ENSG00000166226 KIRP 0.0021 high
ENSG00000166226 LUAD 0.00012 high
ENSG00000166226 PCPG 0.014 high
ENSG00000166226 THYM 0.017 low
ENSG00000166226 BRCA 0.0034 high
ENSG00000166226 COAD 0.009 low
ENSG00000166226 ESCA 0.0054 high
ENSG00000166226 OV 0.0099 low
ENSG00000166226 DLBC 0.001 low
ENSG00000166226 KIRC 0.0024 low
ENSG00000166226 PRAD 0.00052 high
ENSG00000166226 LAML 0.037 low
ENSG00000166226 SKCM 0.0029 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000166226 LUSC Amp 2.519454 0.249684 0.560020 0.355289
ENSG00000166226 LUAD Amp 13.720636 0.323099 0.655613 0.317829
ENSG00000166226 ACC Amp 1.248228 0.328211 1.207064 0.766667
ENSG00000166226 UCS Amp 1.136262 0.565953 0.992150 0.303571
ENSG00000166226 SARC Amp 57.961201 1.645957 2.061415 0.350195
ENSG00000166226 GBM Amp 10.247234 0.196826 1.246189 0.102253
ENSG00000166226 PAAD Amp 1.677439 0.114693 0.719556 0.146739
ENSG00000166226 ESCA Amp 4.777560 0.466993 0.893881 0.271739
ENSG00000166226 SKCM Amp 6.769179 0.285700 0.967235 0.158038
ENSG00000166226 HNSC Amp 9.035063 0.264565 0.789537 0.195402
ENSG00000166226 TGCT Amp 2.397247 0.195040 0.566469 0.660000
ENSG00000166226 BLCA Amp 23.603377 0.609807 1.098361 0.296569
ENSG00000166226 BRCA Amp 13.334813 0.295000 0.735292 0.251852
ENSG00000166226 STAD Amp 16.566556 0.426923 0.920408 0.249433