Ensembl ID ENSG00000165702 Gene ID 8328 Accession 4238
Gene Symbol GFI1B Alias BDPLT17;ZNF163B Full Name growth factor independent 1B transcriptional repressor
Position 9 : 132945551 - 132991687 Length 46137 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

ENSG00000165702 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000165702 GFI1B -2.2 7.95e-13 COAD
ENSG00000165702 GFI1B -1.7 1.28e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000165702 GFI1B AML 17156408
ENSG00000165702 GFI1B cancer 20052764
ENSG00000165702 GFI1B tumors 23910958
ENSG00000165702 GFI1B childhood cancer 25043047
ENSG00000165702 GFI1B acute myeloid leukemia (AML) 26851695
ENSG00000165702 GFI1B cancer 28401061
ENSG00000165702 GFI1B AML 29326122
ENSG00000165702 GFI1B tumor 31649884
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000165702 GFI1B SARC 0.0035 low
ENSG00000165702 GFI1B UCEC 0.014 high
ENSG00000165702 GFI1B THCA 0.015 low
ENSG00000165702 GFI1B LGG 5e-04 high
ENSG00000165702 GFI1B LUSC 0.011 high
ENSG00000165702 GFI1B HNSC 0.013 low
ENSG00000165702 GFI1B READ 0.0034 low
ENSG00000165702 GFI1B KIRP 0.013 high
ENSG00000165702 GFI1B THYM 0.033 high
ENSG00000165702 GFI1B BRCA 0.011 low
ENSG00000165702 GFI1B DLBC 0.022 high
ENSG00000165702 GFI1B KIRC 0.042 low
ENSG00000165702 GFI1B PRAD 0.016 low
ENSG00000165702 GFI1B LAML 0.041 high
ENSG00000165702 GFI1B CESC 0.00055 low
ENSG00000165702 GFI1B LIHC 0.024 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000165702 GFI1B SARC Del 2.002877 0.157132 0.512278 0.245136
ENSG00000165702 GFI1B UCEC Del 1.464939 0.057648 0.539672 0.244898
ENSG00000165702 GFI1B OV Del 5.516363 0.252805 0.572543 0.588946