Ensembl ID ENSG00000165280 Gene ID 7415 Accession 12666
Gene Symbol VCP Alias p97;TERA;CDC48;FTDALS6 Full Name valosin containing protein
Position 9 : 35053928 - 35072668 Length 18741 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients. [provided by RefSeq, Aug 2017]

ENSG00000165280 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000165280 0.41 1.11e-19 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000165280 tumor 12560433
ENSG00000165280 tumor 12829673
ENSG00000165280 tumor 14760088
ENSG00000165280 tumor 14761919
ENSG00000165280 prostate cancer 15131036
ENSG00000165280 tumor 15231524
ENSG00000165280 tumor 15319251
ENSG00000165280 tumor 15452376
ENSG00000165280 follicular thyroid cancer 16189643
ENSG00000165280 cancer 16234241
ENSG00000165280 colon cancers 17166906
ENSG00000165280 cancer 17200190
ENSG00000165280 cancers 17368566
ENSG00000165280 tumor 18279508
ENSG00000165280 cancer 18284922
ENSG00000165280 cancer 18544453
ENSG00000165280 pituitary tumor 18570652
ENSG00000165280 cancer 18798739
ENSG00000165280 lung cancer 19294702
ENSG00000165280 cancers 19356220
ENSG00000165280 non-small-cell lung cancer 19949019
ENSG00000165280 cancer 20137940
ENSG00000165280 tumor 20522600
ENSG00000165280 Tumor 20842219
ENSG00000165280 tumor 20876349
ENSG00000165280 cancer 21085581
ENSG00000165280 cancers 22028587
ENSG00000165280 tumor 22216170
ENSG00000165280 cancer 22449146
ENSG00000165280 tumor 22536440
ENSG00000165280 cancer 22686199
ENSG00000165280 Cancers 22870330
ENSG00000165280 hepatocellular cancer 23041544
ENSG00000165280 tumor 23167185
ENSG00000165280 cancer 23226521
ENSG00000165280 cancer 23233838
ENSG00000165280 tumor 23245311
ENSG00000165280 Cancer 23326097
ENSG00000165280 gastric cancer 23383273
ENSG00000165280 non-small-cell lung cancer 23412975
ENSG00000165280 breast cancer 23613850
ENSG00000165280 tumour 23722536
ENSG00000165280 cancers 23755301
ENSG00000165280 cancer 23892893
ENSG00000165280 pancreatic cancer 23989979
ENSG00000165280 tumor 24096480
ENSG00000165280 cancer 24152492
ENSG00000165280 tumor 24377547
ENSG00000165280 ovarian tumor 24610782
ENSG00000165280 cancer 24878061
ENSG00000165280 cancer 25009651
ENSG00000165280 oral cancer 25060540
ENSG00000165280 tumour 25084388
ENSG00000165280 tumor 25187455
ENSG00000165280 cancer 25385277
ENSG00000165280 tumors 25463965
ENSG00000165280 cancer 25474526
ENSG00000165280 breast cancer 25483453
ENSG00000165280 lung tumors 25970786
ENSG00000165280 prostate cancer 26065901
ENSG00000165280 lung cancer 26081366
ENSG00000165280 cancer 26104798
ENSG00000165280 tumor 26168958
ENSG00000165280 cancer 26720340
ENSG00000165280 cancer 26934314
ENSG00000165280 cancer 27072583
ENSG00000165280 cancer 27086912
ENSG00000165280 thyroid cancer 27308392
ENSG00000165280 tumor 27344168
ENSG00000165280 tumor 27434122
ENSG00000165280 cancer 27524292
ENSG00000165280 cancer 27729187
ENSG00000165280 ovarian cancer 27729194
ENSG00000165280 Gastric cancer 27729735
ENSG00000165280 Cancer 28032027
ENSG00000165280 cancer 28036256
ENSG00000165280 cancer 28122154
ENSG00000165280 GBM 28131906
ENSG00000165280 thyroid cancer 28279065
ENSG00000165280 cancer 28322292
ENSG00000165280 cancer 28494016
ENSG00000165280 cancer 28526689
ENSG00000165280 colorectal cancer 28689657
ENSG00000165280 tumour 29211715
ENSG00000165280 Cancer 29367883
ENSG00000165280 Cancer 29521227
ENSG00000165280 prostate cancer 29693262
ENSG00000165280 GBM 29743287
ENSG00000165280 cancer 30112292
ENSG00000165280 prostate cancer 30247093
ENSG00000165280 non-small cell lung cancer 30606672
ENSG00000165280 cancer 30610116
ENSG00000165280 cancer 30626938
ENSG00000165280 tumor 30643422
ENSG00000165280 cancer 30830772
ENSG00000165280 esophageal cancer 31024994
ENSG00000165280 cancer 31358864
ENSG00000165280 cancer 31368616
ENSG00000165280 cancer 31391554
ENSG00000165280 tumor 31454136
ENSG00000165280 cancer 31456945
ENSG00000165280 thyroid cancers 31672844
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000165280 MESO 0.00076 low
ENSG00000165280 STAD 0.032 low
ENSG00000165280 UVM 0.0014 high
ENSG00000165280 PAAD 0.01 low
ENSG00000165280 UCEC 0.0013 low
ENSG00000165280 ACC 0.0055 high
ENSG00000165280 LGG 0.0019 high
ENSG00000165280 READ 0.0019 low
ENSG00000165280 KICH 0.042 high
ENSG00000165280 LUAD 0.017 high
ENSG00000165280 UCS 0.014 high
ENSG00000165280 DLBC 0.016 low
ENSG00000165280 LAML 0.0017 high
ENSG00000165280 CESC 0.012 low
ENSG00000165280 LIHC 0.00087 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000165280 LUSC Amp 7.798742 0.360334 0.714610 0.269461
ENSG00000165280 GBM Del 1.483583 0.061732 0.634726 0.301560
ENSG00000165280 PAAD Amp 2.177312 0.130083 0.691242 0.119565
ENSG00000165280 HNSC Amp 9.035063 0.264483 0.756212 0.260536
ENSG00000165280 STAD Amp 1.110151 0.144361 0.512436 0.201814